A hierarchical model for the development of cerebral arteriovenous malformations.
Ramey Wyatt L, Martirosyan Nikolay L, Zabramski Joseph M, +2 more·Clinical neurology and neurosurgery
OBJECTIVE: Cerebral arteriovenous malformations (AVMs) are vascular lesions whose pathogenesis, although not fully elucidated, is likely multifactorial. Recent research investigating vessel development suggests a potential hierarchical model in which capillary sprouts from higher-flow arteries give rise to lower-flow v…