44,715 papers found

BACKGROUND/OBJECTIVES: Early childhood caries (ECC) and saliva have been studied across disparate domains, including microbiome, fluoride, immune, oxidative-stress, and neuroendocrine research. However, the ECC-saliva literature has not previously been mapped as a connected system using modern natural language processi…

This paper explores the role of metrology in the assessment of image quality in the field of radiomics. Image Quality Assessment (IQA) is central to ensuring the reliability and reproducibility of radiomic analyses, as it directly affects the accuracy of feature extraction and segmentation, ultimately impacting diagnos…

OBJECTIVES: To assess the impact of ceftazidime-avibactam on 30-day all-cause mortality in patients with OXA-48 producinginfections, in comparison to alternative best available therapy (BAT). METHODS: Systematic review and meta-analysis of observational studies comparing 30-day mortality outcomes in patients infected…

OBJECTIVES: Previous studies have identified the crucial role of provider-client communication in healthcare experiences, but there lacks a comprehensive overview regarding the experiences of transgender and gender non-binary (TGNB) individuals. This review aimed to gain insights into best practices and pitfalls in lan…

BACKGROUND AND PURPOSE: Rapidly progressive dementia (RPD) represents a heterogeneous group of clinical dementia syndromes characterized by a precipitous decline in cognitive function, typically occurring over weeks to months, with diverse underlying etiologies. To elucidate the evolving etiological spectrum of RPD and…

STUDY DESIGN: Systematic review and meta-analysis. OBJECTIVE: To evaluate inter- and intra-observer reliability of the Lenke classification for adolescent idiopathic scoliosis (AIS) and identify methodological factors influencing agreement. The Lenke system is widely used in AIS surgical planning. While initial report…

BACKGROUND: In Africa, ongoing challenges posed by zoonotic foodborne diseases highlight the need to improve control practices. This review aims to present a structured overview by summarizing documented practices in African abattoirs, factors influencing the implementation of either poor or good practices, and the rec…

INTRODUCTION: Psycho-spiritual distress remains one of the most prevalent and pressing concerns throughout the cancer survivorship journey, impacting their existential integrity. Various yoga interventions have been examined for their potential to alleviate this distress, but their effects in cancer patients varied. M…

BACKGROUND: This study aimed to evaluate the clinical effect of aloe vera gel as an adjunct to scaling and root planing (SRP) on plaque index (PI), gingival index (GI), and probing pocket depth (PPD) in periodontitis treatment. METHODS: Randomized controlled trials (RCTs) were included, focusing on aloe vera gel as an…

BACKGROUND AND OBJECTIVE: Esophageal squamous cell carcinoma (ESCC) is a significant global health challenge characterized by increasing incidence and generally poor prognosis. The search for novel biomarkers and therapeutic targets is crucial for improving patient outcomes. Long non-coding RNAs (lncRNAs) have emerged…

BACKGROUND: Cancer treatments such as chemotherapy immunotherapy and radiotherapy are associated with serious adverse effects that affect a patient's physiological functioning and physical appearance, contribute to financial toxicity, reduce quality of life, and increase the risk of treatment discontinuation. This syst…

OBJECTIVE: To explore effectiveness of non-pharmacological interventions in fear of childbirth. METHODS: All published literature were searched from three databases (Pubmed, Cochrane CENTRAL, and Web of Science) as of April 2024. The risk of bias of the included studies was assessed using the Cochrane Systematic Revie…

Emotional and cognitive impairments are comorbidities commonly associated with chronic inflammatory pain. To summarize the rules and mechanisms of comorbidities in a complete Freund's adjuvant (CFA)-induced pain model, we conducted a systematic review of 66 experimental studies identified in a search of three databases…

Glioma is a type of cancer that affects the central nervous system and necessitates a non-invasive diagnostic and prognostic assessment. MicroRNAs (miRNAs) play a crucial role in glioma and can provide valuable information about the prognosis of patients with this condition. MiR-124 is associated with molecules that pl…

BACKGROUND: Post-traumatic elbow stiffness is a common consequence following trauma or surgery, resulting in significant limb disability, with a negative impact on daily life. Although conservative treatment is the first-line approach, it is not yet known which is most suitable and effective. OBJECTIVE: To investigate…

Neuropathic pain (NP) is a heterogeneous group of conditions characterized by the experience of a number of sensory disturbances including pain, burning sensations, paroxysms of stabbing pain, dysesthesias, allodynia, and hyperalgesia. The above-mentioned sensations may occur in a specific dermatome area or other delim…

PURPOSE: To evaluate the effectiveness and safety of trabeculectomy compared to glaucoma drainage devices (GDDs) in managing uveitic glaucoma (UG). DESIGN: Systematic review. METHODS: We searched seven electronic databases (PubMed, Scopus, Web of Science, ScienceDirect, EMBASE, CENTRAL, and Google Scholar) to compare…

BACKGROUND: Multiple Sclerosis (MS) is a chronic neurodegenerative disease of the central nervous system with a significant impact on mobility and balance function. Telerehabilitation is an emerging branch of telemedicine which has the potential to deliver rehabilitation remotely through the use of information and comm…

BACKGROUND: Gestational diabetes (GD) can threaten the health of both the mother and the foetus if it is not effectively managed. While there exists a growing body of research on self-management interventions for GD, there is a lack of reviewed studies regarding the various self-management interventions in Africa. The…

OBJECTIVE: This systematic review aimed to describe and evaluate the caries patterns among the 21st century preschool children globally. METHOD: Six electronic databases (Pubmed, Embase, Medline, Web of Science, EBSCOhost, and Scopus) were searched using predetermined terms. Dual independent screening of all retrieved…