5,087,135 papers found

The cause of colorectal cancer (CRC) is multifactorial, involving both genetic variants and environmental risk factors. We systematically searched the MEDLINE, EMBASE, China National Knowledge Infrastructure (CNKI) and Wanfang databases from inception to December 2016, to identify systematic reviews and meta-analyses o…

BACKGROUND: Intrauterine administration of hCG has been considered as a promising IVF add-on before embryo transfer to improve fertility outcomes. A Cochrane review and four more recent systematic reviews all showed improved clinical pregnancy rates and/or live birth rates following intrauterine administration of hCG,…

BACKGROUND & AIMS: N-3 (omega-3) polyunsaturated fatty acids (n-3-PUFA) have been hypothesized to enhance/maintain skeletal muscle mass, strength, and physical function. We conducted an overview of reviews of n-3 fatty acid monotherapy supplementation and examined whether the evidence supports the effects in healthy yo…

A substantial number of patients with autosomal dominant polycystic kidney disease (ADPKD) undergo a nephrectomy, especially in workup for a kidney transplantation. Currently, there is no evidence-based algorithm to guide clinicians about which patients should undergo nephrectomy, the optimal timing of this procedure,…

Intimate partner violence (IPV) is a widespread social, public health, and human rights problem. Empirical investigation of IPV risk factors can promote evidence-based assessment tools and effective prevention and intervention. This overview is a pioneering synthesis of systematic reviews (SRs) of IPV risk factors. Sys…

The International Liaison Committee on Resuscitation conducts continuous reviews of new, peer-reviewed, published first aid and cardiopulmonary resuscitation science and publishes more comprehensive reviews every 5 years. The First Aid chapter of theaddresses all published evidence reviewed by the First Aid Task Force…

OBJECTIVE: This study reassessed systematic reviews on cryotherapy efficacy following total knee arthroplasty (TKA). METHODS: Ten databases were searched from January 1, 2018 to September 15, 2023 for relevant systematic reviews. Two researchers independently screened articles and extracted data. RESULTS: Five system…

BACKGROUND: Efficient, equitable health research depends on understanding why people decide to take part. The aims of this overview were to update the version published in 2020, identifying psychosocial influences on participation and mapping them to recruitment research and psychological theory. METHODS: Searches wer…

BACKGROUND: The cancer burden in the Nordic European countries remains substantial, but new treatment approaches, such as targeted therapy, have increased the survival of cancer patients. During and following cancer treatment regimens, however, patients' quality of life may be severely affected by sequelae, including c…

To (1) summarize pooled prevalence and incidence rates of concussion by type of sport and (2) synthesize the differences in prevalence or incidence rates of concussion by type of sports in terms of sex, age, type of session, and level of competition.An overview of systematic reviews with meta-analysis.CINAHL, Embase, E…

Treatment of relapsed and refractory myeloid leukemia in Down syndrome (r/r ML-DS) poses significant challenges, as prognosis is dire and there is no established standard treatment. This guideline provides treatment recommendations based on a literature review and collection of expert opinions, aiming to improve overal…

The 2023 International Olympic Committee (IOC) consensus statement on Relative Energy Deficiency in Sport (REDs) notes that exposure to low energy availability (LEA) exists on a continuum betweenandLEA, with a range of potential effects on both health and performance. However, there is variability in the outcomes of LE…

BACKGROUND: Tuberculosis is a communicable disease of public health concern that inequitably impacts the most vulnerable populations worldwide. Vulnerable populations are those with a high risk for tuberculosis disease and whose disadvantaged or marginalised socioeconomic position limits their access to the health syst…

BACKGROUND: National guidelines for rational opioid prescribing for acute postoperative pain are needed to optimise postoperative pain control and function whilst minimising opioid-related harm. OBJECTIVES: This overview of systematic reviews aims to summarise and critically assess the quality of systematic reviews re…

OBJECTIVE: The purpose of this study was to determine the frequency and methods of conflicts of interest (COI) reporting in published dry needling (DN) studies and to determine the frequency of researcher allegiance (RA). METHODS: A pragmatic systematic search was undertaken to identify DN studies that were included i…

OBJECTIVE: To evaluate the effect of non-invasive brain stimulation (NIBS) in improving limb motor dysfunction and daily living activity during at the phase of acute stroke. MATERIALS AND METHODS: Randomized controlled trials about the effect of NIBS on hemiparesis in acute stroke were retrieved from databases of Chin…

INTRODUCTION: Coeliac disease and dermatitis herpetiformis are immune-mediated diseases triggered by the consumption of gluten in genetically predisposed individuals. These guidelines were developed to provide general practitioners, paediatricians, gastroenterologists, and other clinicians with an overview on the diagn…

BACKGROUND: The significance of evidence-based surgery has resulted in a shift towards producing high-quality surgical research. The aim of this bibliometric analysis was to evaluate trends in publication of general surgery research in Australia from 2000 to 2020. METHODS: General surgery publications including clinic…

Comprehensive endometrial cancer staging requires mandatory lymph node status assessment. However, some randomized clinical studies show that full lymphadenectomy may have no therapeutic benefit in patients presented with early-stage disease. Sentinel lymph node mapping can be considered in patients at low to intermedi…

The purpose of this overview was to assess different antibiotic regimens used in orthognathic surgery and to establish an evidence-based protocol so that beneficial and adverse effects can be determined. A comprehensive literature search for systematic reviews and/or meta-analyses was conducted in MEDLINE (PubMed), EMB…