Meta-analysis for trials in early breast cancer: a recent update.
Annals of oncology : official journal of the European Society for Medical Oncology
Abstract not available
Searching PubMed for “Meta-analysis” and checking full-text availability…
for “Meta-analysis” · Showing 41–60 · 2217 ms
Annals of oncology : official journal of the European Society for Medical Oncology
Abstract not available
Li Zhe, Liu Sha, Liu Qian, +4 more·Prostaglandins & other lipid mediators
Several studies have evaluated the effects of resveratrol supplementation on lipid profile parameters in humans and have demonstrated varying results. We systematically evaluated the literature and performed an umbrella meta-analysis of the effects of resveratrol supplementation on lipid profile. A comprehensive litera…
Ferraz M B, Tugwell P, Goldsmith C H, +1 more·The Journal of rheumatology
At present there is no widely accepted therapy for ankylosing spondylitis (AS), a progressive debilitating disease. The effectiveness of sulfasalazine in AS still lacks strong evidence, as well, the magnitude of its benefit is unknown. A meta-analysis was carried out to assess the effectiveness of sulfasalazine in AS.…
Samartsidis Pantelis, Montagna Silvia, Laird Angela R, +3 more·Research synthesis methods
Coordinate-based meta-analyses (CBMA) allow researchers to combine the results from multiple functional magnetic resonance imaging experiments with the goal of obtaining results that are more likely to generalize. However, the interpretation of CBMA findings can be impaired by the file drawer problem, a type of publica…
Schena F P, Montenegro M, Scivittaro V·Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
An overview of the papers published in the last 10 years was performed to evaluate whether treatment with currently available drugs was beneficial in patients with primary IgA nephropathy (IgAN). Eight selected papers involving 196 IgAN patients with moderate or heavy proteinuria, associated in some cases with the neph…
Mao Qiqi, Lin Yiwei, Zheng Xiangyi, +3 more·Cancer causes & control : CCC
OBJECTIVE: Epidemiologic studies have reported conflicting results relating alcohol intake to bladder cancer risk. A meta-analysis of cohort and case-control studies was conducted to pool the risk estimates of the association between alcohol intake and bladder cancer. METHODS: Eligible studies were retrieved via both…
Wu Bingwei, Gao Mingju, Zhang Yixuan, +1 more·PeerJ
BACKGROUND: Acne is a common skin condition that can cause permanent scarring and profoundly affect patients' quality of life. Despite the increasing diversity of acne scar treatments, there is a dearth of comprehensive evidence-based guidelines to help clinicians and patients make the best choices. This study aimed to…
Pace N L·Anesthesia and analgesia
Meta-analysis is a term used to describe statistical methods for evaluating a series of research reports; this analysis transcends the limitations that may be inherent in each of the individual studies summarized. Forty-five research reports of clinical trials for the prevention of myalgias after succinylcholine were a…
Taylor Alan, Kim-Cohen Julia·Development and psychopathology
As studies of measured gene-environment interactions (G x E) in developmental psychopathology gain momentum, methods for systematically and quantitatively summarizing effects across multiple studies are urgently needed. Meta-analyses of G x E findings are critical for evaluating the overall statistical and theoretical…
Wilkinson G, Balestrieri M, Ruggeri M, +1 more·Psychological medicine
Meta-analysis of 19 double-blind placebo-controlled trials of antidepressants (N = 13) and benzodiazepines (N = 6) for patients with panic disorders showed that active treatment had 25% greater success rate than placebo over a mean duration of 14 weeks. There were no statistically significant differences observed betwe…
Xie Jingyi, Jin Mingyuan, Guo Jindong, +3 more·The spine journal : official journal of the North American Spine Society
BACKGROUND CONTEXT: Nonspecific neck pain causes chronic pain, functional impairment, and adversely affects quality of life. It remains unclear whether exercise or other nonphysical therapies are more effective in improving nonspecific neck pain (NSNP), and the optimal dosage of exercise for alleviating NSNP has yet to…
Henry D, Cook D·Gastroenterology
Abstract not available
Parent M, LeBel M·DICP : the annals of pharmacotherapy
Several fluoroquinolones currently under investigation or on the market potentially interact with theophylline. In this study, meta-analysis methodology was used to evaluate the significance of findings from quinolone-theophylline interaction studies. Two major databases were searched: Index Medicus (from 1986 to March…
Petruzzello S J, Landers D M, Hatfield B D, +2 more·Sports medicine (Auckland, N.Z.)
The relationship between exercise and anxiety has been extensively examined over the last 15 years. Three separate meta-analysis were conducted to quantitatively review the exercise-anxiety literature for state anxiety, trait anxiety and psychophysiological correlates of anxiety. Such a procedure allows tendencies of t…
Khairy Yousof, Naghibi Deniz, Moosavi Ahmad, +2 more·Systematic reviews
BACKGROUND: Since the COVID-19 outbreak, preliminary research has shown that some risk-associated conditions increase death and severe complications of the disease, hypertension being one of them. Thus, numerous meta-analyses have been conducted to explore this issue. Therefore, this umbrella review aims to perform a m…
Hirst Lorna, Ntaga Iro, Seehra Jadbinder, +2 more·European journal of orthodontics
BACKGROUND/OBJECTIVES: In systematic reviews (SRs) with a meta-analysis, a subgroup analysis can be utilised to explore heterogeneity of treatment effects across patient characteristics and assess how patient characteristics, types of intervention, or trial characteristics modify the treatment effect. The aim of this m…
Meijer W S, Schmitz P I, Jeekel J·The British journal of surgery
In this study all available clinical trials of antibiotic prophylaxis in biliary tract surgery, published from 1965 to 1988, were examined. Results of 42 randomized, controlled trials (4129 patients), in which a group of patients treated with antibiotics was compared with a group of patients not treated with antibiotic…
Berlin Jesse A, Crowe Brenda J, Whalen Edward, +3 more·Clinical trials (London, England)
BACKGROUND: Meta-analyses of clinical trial safety data have risen in importance beyond regulatory submissions. During drug development, sponsors need to recognize safety signals early and adjust the development program accordingly, so as to facilitate the assessment of causality. Once a product is marketed, sponsors a…
de Jong Valentijn M T, Moons Karel G M, Riley Richard D, +4 more·Research synthesis methods
Many randomized trials evaluate an intervention effect on time-to-event outcomes. Individual participant data (IPD) from such trials can be obtained and combined in a so-called IPD meta-analysis (IPD-MA), to summarize the overall intervention effect. We performed a narrative literature review to provide an overview of…
Jeremic Branislav·International journal of radiation oncology, biology, physics
Abstract not available