11,451,749 papers found

Spirituality and religion are frequently acknowledged as significant contributors to individuals' recovery from substance use disorders. This review focuses on the role that spirituality or religion plays in substance abuse treatment outcomes. Our search of three databases-PubMed, CINAHL, and Psych Info-turned up 29 el…

Generic ophthalmic drug product development is challenging, and innovative methodologies to complement traditional bioequivalence (BE) studies for BE assessment are desirable to promote their evaluation. Ocular physiologically based pharmacokinetic (PBPK) models can provide insight into drug partitioning in eye tissues…

INTRODUCTION: Epstein-Barr virus (EBV), a double-stranded DNA virus, has 2 phases of lytic and latent infection in host cells. After infecting B lymphocytes, EBV becomes persistent in these cells. In healthy individuals, T lymphocytes play a key role in killing EBV-infected B cells. Statistical studies have shown that…

This study's hypothesis is that human immunodeficiency virus-infected patients in the inner city (predominantly injection drug users and ethnic minorities) do not take highly active antiretroviral therapy (HAART) as prescribed and that nonadherence leads to virologic failure. A prospective, observational, 3-month study…

Sex education is a key public health endeavor - preventative for a host of conditions. This study's purpose was to identify barriers to sex education faced by Latinas. We used Qualitative Interpretative Meta-Synthesis to synthesize qualitative studies of Latinas' sex education experiences. We analyzed 13 articles searc…

This study explores endometrial cancer (EC) within the broader context of oncogynecology, focusing on 3,845 EC patients at the Almazov National Research Center. The research analyzes clinical data, employing machine learning techniques like random forest regression and decision tree analysis. Key findings include age-d…

The use of a dyad leadership model involving a physician co-leader and a co-leader with a different background, the dyad co-leader, is gradually increasing in Healthcare Organizations (HCOs). There is a paucity of empirical studies on various aspects of this model. This study's aim was to identify challenges and strate…

It is often difficult for the media and the public to appreciate the role of flawed but contributory epidemiologic research. A study of cell phone use and children's behavior problems (published in this issue) illustrates the ingredients of "inflammatory epidemiology"--there is a common exposure and a common health pro…

Responsiveness defines the prompt, contingent, and appropriate reactions parents display to their children in the context of everyday exchanges. Maternal responsiveness occupies a theoretically central position in developmental science and possesses meaningful predictive validity over diverse domains of children's deve…

The role of psychosocial factors in peptic ulcer remains controversial. We have investigated the relationship between socioeconomic status, concrete stressors, and ulcers in a longitudinally followed, population-based cohort, taking confounding risk factors into account. A total of 6,928 adults completed the Alameda Co…

In research involving human subjects, large participation payments often are deemed undesirable because they may provide 'undue inducement' for potential participants to expose themselves to risk. However, although large incentives may encourage participation, they also may signal the riskiness of a study's procedures.…

The issue of job satisfaction among rehabilitation nurses has not been addressed frequently in the literature. This qualitative study was designed to assess rehabilitation nurses' concerns and suggestions for improving the program in a 38-bed acute rehabilitation unit. The study's results indicate that the role of the…

Venous thromboembolism (VTE) occurs at an increased incidence in cancer patients. A cancer-related hypercoagulable state has been considered to play role in this phenomenon. Preclinical data suggest an association between tumor expression of MET proto-oncogene (MET) and a hypercoagulable state, resulting in VTE. We inv…

PURPOSE: The effect of infant formulas sweetened or not with sucrose on primary enamel demineralization and dental biofilm is not known. This study's purpose was to evaluate the effect of infant formula and sucrose association on demineralization of primary enamel and dental biofilm formed. METHODS: A cross-over, spli…

Cyberbullying is a form of online aggression between peers, the prevalence of which varies from 10% to 40% according to studies in different countries. A large share of the scientific literature on cyberbullying tends to individualize and medicalize the causes of the violence, without understanding the context in which…

The calculation of a study's required sample size is one of the most important aspects of the validity of an epidemiological study. Logistic regression often is used in modelling in epidemiology. A simplified method to calculate the sample size for the multiple logistic-regression model was proposed by Hsieh et al. [St…

BACKGROUND: Cancer stem cells are regarded as the origin of tumors that can proliferate, relapse, and metastasize. Nanog, with its capacity to maintain the pluripotency and regulate proliferation and prevent differentiation, is one of the most important core markers of cancer stem cells. Studying the role of Nanog in e…

This research aimed to investigate the mediating function of Green Employee Empowerment (GEE) in the relationship between Green Human Resource Management practices (GHRM) and the environmental performance of small and medium-sized enterprises (SMEs) in Ghana, drawing on the Ability-Motivation-Opportunity (AMO) theory.…

Chronic non-communicable diseases represent a major public health problem, requiring more effective investigation and control by government agencies. The aim of this study was to correlate the mortality rate for oral cancer in Brazilian State capitals from 1998 to 2002 with socioeconomic factors collected in the 2000 c…

While there has been considerable inquiry into how religion may help Christians deal with stressful life events (SLEs), only limited research has been conducted on the impact SLEs might have on religion. This study's purpose was to provide an in-depth analysis of this relationship in a sample of highly religious Christ…