11,526,404 papers found

OBJECTIVE: The perception of insufficient milk is a common problem among mothers that is associated with the breastfeeding process and psychological well-being. This study examined the relationship between mothers' personality traits, perceived levels of social support, and perceptions of insufficient milk. METHODS: T…

P-values are often calculated when testing hypotheses in quantitative settings, and low P-values are typically used as evidential measures to support research findings in published medical research. This article reviews old and new arguments questioning the evidential value of P-values. Critiques of the P-value include…

In order to become knowledgeable consumers of nursing research, nursing students must be able to critically read research and determine the study's value for nursing practice. As the number of nursing intervention studies rises and research topics are studied more extensively, the use of meta-analysis in the discipline…

A histopathologic analysis of regional lymph node specimens in 48 patients with previously untreated squamous cell carcinoma of the larynx was performed to determine which parameters, if any, correlated with 3-year patient survival. The presence of sinus histiocytosis in lymph nodes containing metastatic squamous cell…

This chapter focuses on the development and evaluation of prediction models for heart failure using machine learning techniques. By analyzing patient characteristics and applying algorithms such as random forest, gradient boosting, and others, highly accurate predictions were achieved. The findings demonstrate that mac…

Generic ophthalmic drug product development is challenging, and innovative methodologies to complement traditional bioequivalence (BE) studies for BE assessment are desirable to promote their evaluation. Ocular physiologically based pharmacokinetic (PBPK) models can provide insight into drug partitioning in eye tissues…

BACKGROUND: Colorectal cancer is a heterogeneous disease that leads to metabolic disorders due to multiple upstream genetic and molecular changes and interactions. The development of new therapies, especially herbal medicines, has received much global attention.is a medicinal plant. Its gum is used in healing known ail…

A recent study comparing physicians and large language models on clinical reasoning tasks has received widespread attention. In this News and Perspectives article, JMIR Correspondent Shalini Kathuria Narang speaks to one of the study's researchers and reports on the real-world implications that can and cannot be drawn…

A controversial study has claimed that most cancer is due to random processes unrelated to external causes, i.e., bad luck. The controversy has obscured the study's importance toward spurring scientific understanding of how best to prevent cancer.

In 1998 Piper-Terry and Downey found that women accepted friends' bogus test interpretations more readily than did men and the researchers attributed this to women's helpfulness. Layne countered that women are more open and thus rationally expected their friends' interpretations to be more accurate. Later Downey asked…

BACKGROUND: This article examines the ethical implications of using respondent-driven sampling (RDS) to conduct HIV behaviour surveillance among injection drug users (IDUs) in Chicago. Ethnographic inquiry illustrates how the design and implementation of RDS invites if not promotes manifold violations of federal guidel…

In research involving human subjects, large participation payments often are deemed undesirable because they may provide 'undue inducement' for potential participants to expose themselves to risk. However, although large incentives may encourage participation, they also may signal the riskiness of a study's procedures.…

This letter critically evaluates Jiang's article on the differentiation of benign and malignant liver lesions using Emax and platelet count. Despite notable findings, significant methodological and interpretative limitations are identified. The study lacks detailed assay conditions for Emax measurement, employs inadequ…

Many college women report engaging in weight control strategies, yet little is known about which strategies are used and how often. The current study's goal was to evaluate the factor structure of a comprehensive list of weight control behaviors used in the previous 24-hours.Undergraduate women ( = 286) w…

AIM: The aim was to determine whether there are relationships among transformational leadership, safe team climate, knowledge sharing and reflection, and team performance in nursing and social work teams. BACKGROUND: Based on organisational learning theory, we hypothesized that transformational leadership could create…

For decades, states have passed legislation to mandate reporting of criminal conduct and the abuse of vulnerable persons. Four types of mandatory reporting laws have been enacted, including laws that require reports of injuries associated with crime or due to use of certain weapons, abuse of children, abuse of vulnerab…

PURPOSE OF REVIEW: Sinusitis is a leading reason for outpatient antibiotic use, but symptoms are nonspecific. We review potential methods that might enhance the ability to appropriately prescribe antibiotics. RECENT FINDINGS: The evidence base for antibiotic use in acute rhinosinusitis is strongest in studies with str…

Successful participant recruitment for pediatric studies can be challenging and even result in study discontinuation. In conducting a 2-year pilot study for a pediatric mobile health (mHealth) asthma intervention, a group of researchers experienced multiple barriers and failures in all 4 areas of recruitment: generatin…

Functional magnetic resonance imaging (fMRI) neurofeedback can train subjects to control their brain activity with real-time processing and high spatial resolution, as many advances in MRI data acquisition methods, computer hardware, and processing algorithms have improved the sensitivity and speed of fMRI neurofeedbac…