11,613,807 papers found

The purpose of this literature review was to compare the methodology used in the most recently published cost-effectiveness studies of antihypertensive treatments, and to identify methodological strengths and weaknesses that indicate the study's potential as a useful, decision-making tool. Based on the results of a sea…

UNLABELLED: Small observational studies have demonstrated an association between high ERCC1 expression level and poor prognosis in advanced NSCLC treated with platinum-based chemotherapy. This meta-analysis presents pooled estimates of association from 11 studies. High ERCC1 patients had lower response rates and higher…

OBJECTIVE: Fluorodeoxyglucose PET/computed tomography (FDG PET/CT) is effective in detecting large vessel vasculitis. Digital PET cameras have improved spatial resolution compared with analog PET, resulting in more prominent physiological uptake in arterial walls. This study's goal was to define qualitative normal vari…

BACKGROUND: Musculoskeletal (MSK) spinal pain encapsulates various conditions including lumbar (low back), cervical (neck), and thoracic pain that significantly impact individual and global health. While clinical aspects of spinal pain have been well-studied, understanding patients' personal narratives and lived experi…

Healthcare systems are transforming from the traditional volume-based model of healthcare to a value-based model of healthcare. Value generation in healthcare is about emphasising the health outcomes achieved by patients and organisations while maintaining an optimal relationship with costs. This scoping review aimed t…

PURPOSE OF REVIEW: Low back pain (LBP) is a prevalent condition that is associated with diminished physical function, poor mental health outcomes, and reduced quality of life. Peripheral nerve stimulation (PNS) is an emerging modality that has been utilized to treat LBP. The primary objective of this systematic review…

BACKGROUND: Drug-eluting stents have been seen as an attractive alternative to bare-metal stents for percutaneous coronary interventions (PCIs) because of the decreased need for revascularization. However, comparative clinical trials have shown no difference in patient outcomes, and drug-eluting stents are considerably…

The principal aim of this investigation is to identify pivotal biomarkers linked to the prognosis of osteosarcoma (OS) through the application of artificial intelligence (AI), with an ultimate goal to enhance prognostic prediction. Expression profiles from 88 OS cases and 396 normal samples were procured from accessibl…

Human vaginal microorganisms play an important role in maintaining good health throughout the human life cycle. An imbalance in the vaginal microbiota is associated with an increased risk of pelvic inflammatory disease (PID). This study aimed to characterize and compare vaginal microbial profiles of premenopausal Korea…

BACKGROUND: The COVID-19 pandemic has had a profound impact worldwide. This study sought to assess the pandemic's psychological impact on the Israeli public. METHODS: Using mixed methods we assessed Israeli adults during the COVID-19 outbreak. In the quantitative study, participants (N=1407) completed an online batter…

Expanded access is a treatment use of investigational drugs, biologicals or medical devices outside of clinical trials. The purpose of our study was to assess self-reported conflicts of interest (COIs) in oncology expanded access studies. One hundred fifty-eight oncology expanded access studies published from 2013 thro…

BACKGROUND: Anxiety is a common mental health problem in the general population, and is associated with functional impairment and negative impacts upon quality of life. There has been increased concern about university students' mental health in recent years, with a wide range of non-specific anxiety rates reported wor…

Pregnancy rates after vasectomy reversal vary among different reporting surgeons. To study those patients who are most likely to achieve pregnancy after vasectomy reversal, and to eliminate the effect of variations in surgical technique and operative findings on surgical outcome, the pregnancy rate after vasectomy reve…

Workers frequently engage in nonneutral body postures that increase their risk of developing musculoskeletal disorders. The purpose of this study was to extend previous research by evaluating whether the provision of information plus artificial intelligence (AI)-enhanced video feedback could improve manufacturing worke…

Social media has become an essential aspect of our lives, especially for adolescents, in this digital age. Platforms like Instagram, Facebook, TikTok, and many more have created a hyperreal world that blurs the line between reality and fantasy. This can have significant consequences, particularly when it comes to adole…

OBJECTIVE: Pesticide exposure via take-home pathways is a major health concern among farmers. However, little is known about the effects of pesticide take-home pathways on small-scale Hmong farmers in the Central Valley. This study explored factors that contribute to pesticide exposure via the take-home pathway among s…

The study's aim is to explore the experiences of people with advanced cancer and professionals participating in a program with focus on rehabilitation and palliative care. The study is based on two adjusted rehabilitation programs for 33 people with advanced cancer and 12 professionals. An observational study was condu…

There has been a call to action from much of the community to urgently investigate stress and well-being during the global health crisis instigated by COVID-19. This study seeks to investigate well-being, meaning in life, and psychological flexibility in relation to COVID-19 stress. Participants of the study consisted…

Traditional predictors of academic performance in college, such as measures of verbal and mathematical abilities [i.e., Scholastic Aptitude Test (SAT)] and academic achievement (i.e., high school GPA), often account for less than 25% of the variance in college performance, thus leaving a considerable amount of variance…

Last year, a study appeared that questioned the generally held assumption of a generic coupling between electrical and hemodynamic signs of neural activity (Sirotin and Das, 2009). Although the findings of that study can barely surprise the specialists in the field, it has caused a considerable confusion in the nonspec…