97,488 papers found

BACKGROUND: The use of psychotropic drugs has increased over recent years in France. GPs are the first prescribers, especially for older patients. AIM: To analyse discrepancies between GPs' opinions and practice when prescribing psychotropic drugs to older patients. SETTING: Postal surveys sent to GPs all over mainla…

OBJECTIVE: To assess the prevalence and risk factors for sunburn in young people. METHODS: Population-based cross-sectional study using a multiple-stage sampling carried out with people living in the urban area of Pelotas, Southern Brazil, between October and December 2005. Data was collected from interviews with 1.60…

This report uses routinely collected data in the Defense Medical Surveillance System (DMSS) to characterize the incidence and burden of medical conditions throughout the careers of service members separating from the active component of the U.S. Armed Forces between 1 October 2014 and 30 September 2015. Three surveilla…

PURPOSE: Overtreatment in terminally ill cancer patients is very common worldwide, but whether patients will benefit from aggressive care remains obscure. This study aimed to explore the value of aggressive interventions in the end of life in adult patients with advanced solid tumors. METHODS: All adult patients who d…

BACKGROUND: It is not known whether the current molecular classification of blood coagulation disorders into severe (0-1%), moderate (1-5%) and mild (5-40% factor activity remaining) corresponds to the actual clinical situation or is in the patients best interest. METHODS: A questionnaire-based study of 244 patients.…

CONTEXT: In amyotrophic lateral sclerosis (ALS), equal care is important, given that the disease often has complex symptoms at the end of life. OBJECTIVES: The aim was to study the possible associations between demographic and clinical factors, including age, sex, and frailty, with acute healthcare utilization in the…

BACKGROUND: Young mothers aged 15 to 24 years are particularly at higher risk of adverse health outcomes during childbirth. Delivery in health facilities by skilled birth attendants can help reduce this risk and lower maternal and perinatal morbidity and mortality. This study assessed the determinants of health fa…

PURPOSE OF THE STUDY: We propose a different management scheme for painful post-traumatic osteoarthritis of the wrist resulting from pseudarthrosis of the carpal scaphoid bone. We report a prospective series with a maximum follow-up of 16 years. MATERIAL AND METHODS: From 1973 to 1990, we performed 100 first-intention…

To evaluate the influence of carpentry of Bryan disc, including artificial disc coverage ratio and shell angular, on long-term efficacy and complications cervical artificial disc replacement.To retrospectively analyze the clinical data of 86 patients who underwent Bryan disc replacement in Beijing Jishuitan Hospital be…

INTRODUCTION: BAY 81-8973 (Kovaltry®), a recombinant factor VIII (rFVIII) product, was efficacious and well tolerated in paediatric previously treated patients (PTPs) with severe haemophilia A for ≥50 exposure days (EDs) in the LEOPOLD Kids study. Because long-term prophylaxis (≥100 EDs) can provide…

The continuing controversy between proponents of open and closed commissurotomy might be clarified by analysis of late follow-up with modern actuarial techniques that provide a true perspective of patient risk. We have used open mitral commissurotomy exclusively for 15 years in 100 patients. There was one operative dea…

OBJECTIVE: To compare the methods and designs, constructs, publication rate, and location of studies in the past 15 years of pediatric psycho-oncology research, across geographic areas and over time. METHODS: Three recently published reviews on psychological consequences of surviving childhood cancer were reanalyzed a…

This study gives an overview of the suicide rates in Hong Kong in the last 2 decades (1971-1990). It was found that the average suicide rate for the whole population was 11.3 per 100,000 population and it has been quite steady in recent years. The male and female adolescent (age-group 10-24 years) suicide rates were ap…

Growth and sexual development were evaluated in 250 adolescents with beta-thalassemia major. Before transfusion hemoglobin concentration had not been less than 9.5 gm/dl in the last 5 years; desferrioxamine had been administered for 7 to 10 years, including by the subcutaneous route for 3 years. Thirty-seven percent of…

OBJECTIVE: To evaluate the outcome of children with Wilms' tumour over the last 30 years in South Australia. To compare the outcome of children treated before and after 1982, when standard treatment protocols were introduced. METHODOLOGY: Management approaches, survival rates and side-effects of treatment were identif…

OBJECTIVE: To determine whether the prevalence and magnitude of myopia among children and young adults wearing spectacles has increased in Germany from 2000 to 2015. MATERIAL AND METHODS: A total of 1,223,410 refraction values from 278,432 male and 333,273 female subjects between 5 and 30 years of age were analyz…

OBJECTIVE: To assess the clinical characteristics and outcome of a rheumatic fever case-series from a referral hospital over the last 20 years. PATIENTS AND METHODS: Patients under the age of 18 years, diagnosed with rheumatic fever between 1986 and 2007 were retrospectively assessed to estimate the carditis and relap…

OBJECTIVE: The purpose of this review is to offer updating on recent changes in the schedule of active immunization routine in adolescence. METHODS: This review covers specialized medical literature between 1985 and 1996, and follows the recommendations of American Academy of Pediatrics and Advisory Committee on Immun…

OBJECTIVE: To investigate the influence of time since childbirth and other pregnancy factors on the prognosis of premenopausal breast cancer. METHODS: Women who delivered an infant in Nova Scotia, Canada, between 1980 and 2001 were identified from a provincial perinatal database and linked to the Nova Scotia Cancer Re…

OBJECTIVE: Identify factors associated with presence and extension of spinal and sacroiliac joints (SIJ)-MRI lesions suggestive of axial spondyloarthritis (axSpA) in a population-based cohort (Study of Health in Pomerania) aged <45 years. METHODS: Spinal (sagittal T1/T2) and SIJ (semicoronal STIR sequences) MRIs were…