44,713 papers found

BACKGROUND: Psychosocial strategies are commonly used to alleviate anxiety and depression in patients with prostate cancer. However, previous studies have shown inconsistent results. OBJECTIVES: This study examined the effects of psychosocial strategies on anxiety and depression in prostate cancer patients. DATA SOUR…

BACKGROUND: Interest is growing both in implementing a gender perspective in medical research and in developing gender research. However, few models exist that can help researchers who want to develop gender research. OBJECTIVES: The objectives of this article were to analyze gender research compared with sex/gender b…

OBJECTIVES: Cocaine use disorder (CUD) is a chronic condition, often associated with attention deficit hyperactivity disorder (ADHD). No medications have been approved for the treatment of CUD, but methylphenidate (MPH) has been explored as a potential candidate. We conducted a systematic review and meta-analysis to ev…

INTRODUCTION: Central nervous system germ cell tumors (CNS-GCTs) are rare pediatric tumors, categorized into germinomas and non-germinomatous germ cell tumors (NGGCTs). Proton-beam therapy (PBT) has been introduced as an alternative to X-ray therapy (XRT) for minimizing radiation exposure to normal brain tissue, but ev…

BACKGROUND: Primary central nervous system (CNS) tumors are a heterogeneous group of neoplasms, including benign and malignant tumors. Since there are many heterogeneities in the prevalence reported in previous studies on this type of tumor, this study was performed to determine the overall prevalence of different prim…

Auditory temporal processing tests are key clinical measures in order to diagnose central auditory processing disorder (CAPD). Although these tests have been used for decades, there is no up-to-date evidence to determine the effectiveness of detecting the abnormalities in central auditory processing in adults while the…

OBJECTIVE: The purpose of this meta-analysis was to evaluate the diagnostic performance of diffusion-weighted imaging (DWI) for differentiating primary central nervous system lymphoma (PCNSL) from glioblastoma (GBM). MATERIALS AND METHODS: A thorough search of the databases including PubMed, EMBASE, and Cochrane Libra…

ETHNOPHARMACOLOGICAL RELEVANCE: Crinum macowanii is a deciduous bulbous plant which grows in east, central and southern Africa. Crinum macowanii has been used as herbal medicine by the indigenous people of east and southern Africa has for several centuries. The bulb, leaves and roots of C. macowanii are reported to pos…

There is a need for easy-to-use methods to assess training progress in sports and rehabilitation research. The present review investigated whether cardiac acceleration at the onset of physical exercise (HRonset) can be used as a monitoring variable. The digital databases of Scopus and PubMed were searched to retrieve s…

BACKGROUND: The aim of this meta-analysis is to evaluate the central corneal thickness (CCT) measurement differences between Pentacam (Oculus Inc., Germany) and Ultrasound Pachymetry (USP) in normal (unoperated eyes , myopic and astigmatic eyes without corneal disease or topographic irregularity), after laser in situ k…

OBJECTIVE: To review the available evidence regarding the use of linezolid for the treatment of patients with central nervous system (CNS) infections. DATA SOURCES: Relevant studies were identified through searches of the PubMed, Current Contents, and Cochrane databases (publications archived until October 2006). STU…

Central nervous system (CNS) disorders pose a major global health challenge, yet therapeutic development is impeded by the difficulty of delivering effective drug concentrations to the brain. Based on a literature search of PubMed, Scopus, and Google Scholar (1990-2025), this review delineates the current landscape of…

INTRODUCTION: Preclinical and clinical studies reported that 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') can cause adverse effects in the central nervous system (CNS). Recently, preclinical studies have demonstrated that certain psychoactive substances may exacerbate the noxious central effects of MDMA when co-…

BACKGROUND: Central nervous system fungal infections, though rare, may lead to various movement disorders either due to direct fungal invasion or as adverse effects of antifungal drugs. OBJECTIVES: This systematic review aimed to consolidate all published cases and characterize the clinical patterns, mechanisms, and o…

OBJECTIVES: Short bowel syndrome (SBS), characterized by insufficient absorptive surface after extensive intestinal resection, results in chronic intestinal failure and reliance on parenteral nutrition. This meta-analysis aimed to examine the adverse events associated with teduglutide treatment for SBS. METHODOLOGY: C…

OBJECTIVE: This review will analyze the effectiveness of early childhood education interventions to improve complementary feeding practices in children aged 4 to 36 months. INTRODUCTION: Healthy eating habits, which start with food introduction, can influence children's growth and development. Educational actions carr…

PURPOSE: This retrospective systematic literature review aimed to summarize available data regarding epidemiology, etiology, presentation, investigations, differentials, treatment, prevention, monitoring, complications, and prognosis for radiation-induced cavernous malformations (RICMs) in pediatric patients. METHODOL…

PURPOSE: Adaptive servo-ventilation (ASV) is contraindicated for the treatment of central sleep apnea (CSA) in patients with heart failure with reduced ejection fraction (HFrEF), limiting treatment options. Though continuous positive airway pressure (CPAP), bi-level PAP with back-up rate (BPAP-BUR), and transvenous phr…

OBJECTIVE: Childhood primary angiitis of the CNS (cPACNS) is a devastating neurologic disease. No standardized treatment protocols exist, and evidence is limited to open-label cohort studies and case reports. The aim of this review is to summarize the literature and provide informed treatment recommendations. METHODS:…

The current systematic review and meta-analysis of randomized controlled trials (RCTs) was conducted to evaluate the potential effect of melatonin supplementation on blood pressure in patients with metabolic disorders. The following databases were searched until June 2018: PubMed, MEDLINE, EMBASE, Web of Science, and C…