44,713 papers found

OBJECTIVE: Infection of a subdural hematoma is an unusual cause of subdural empyema, with fewer than 50 cases reported in the literature. The appropriate surgical option for this entity has not been determined because of its rarity. We present a case report of a post-traumatic subdural hematoma infected with Escherichi…

OBJECTIVE: The purpose of this study was to explore the association between the TNF-α rs1800629 (also refers as -308G/A) polymorphism and asthma susceptibility. METHODS: We searched the Pubmed, Embase, Cochrane Central Register of Controlled Trials (CENTRAL) and Wanfang databases. Odds ratios (ORs) with 95% conf…

OBJECTIVE: This systematic review assessed the effectiveness of hormone therapy (HT) in patients with a granulosa cell tumor (GCT) of the ovary. METHODS: Medline (OVID), EMBASE (OVID), the Cochrane Central Register of Controlled Trials (CENTRAL), prospective trial registers and PubMed (as supplied by publisher-subset)…

RATIONALE: Psychosocial characteristics likely play an important role in the severity of workplace disability for workers with a respiratory impairment. OBJECTIVES: We performed a systematic review of the available literature to examine the impact of psychosocial characteristics on workplace disability among workers w…

OBJECTIVE: To assess the evidence regarding efficacy of oral amoxicillin compared to standard treatment for WHO-defined severe community acquired pneumonia in under-five children in developing country. DESIGN: Systematic review and meta-analysis of data from published Randomized trials (RCTs). DATA SOURCES: MEDLINE (…

BACKGROUND: Most deaths of infants with chronic lung disease (CLD) are caused by respiratory failure, unremitting pulmonary artery hypertension (PAH) with cor pulmonale, or infection. Although the exact prevalence of PAH in infants with CLD is unknown, infants with CLD and severe PAH have a high mortality rate. Except…

Subclavian artery stenosis has long been treated with great success with bypass surgery. Percutaneous intervention, often used in combination with stent placement, has come into vogue for the past few years as a safe and effective therapeutic modality. This study aimed to compare angioplasty alone with angioplasty foll…

BACKGROUND: Contemporary studies have shown that spontaneous but not procedural myocardial infarction (MI) is related to subsequent mortality. Whether percutaneous coronary intervention (PCI) reduces spontaneous (nonprocedural) MI is unknown. METHODS AND RESULTS: PubMed, EMBASE, and Cochrane Central Register of Contro…

RATIONALE: Conduct disorder (CD) is a common disorder which is typified by a variety of behavioral problems and aggression. Treating CD is a challenge in the field of child and adolescent psychiatry. The use of drugs for this indication is broad despite the lack of systematic knowledge on this subject. OBJECTIVES: Thi…

BACKGROUND: Ménière's disease is characterised by three major symptoms: vertigo, deafness and tinnitus, which may be accompanied by aural fullness, all of which are discontinuous and variable in intensity. While discontinuous, these symptoms are synchronous. Intratympanic application of gentamicin, an ototoxi…

BACKGROUND: Caffeine is widely consumed, and its effect on intraocular pressure (IOP) has been reported in conflicting data. The aim of this meta-analysis was to quantitatively summarize the effect of caffeine on IOP in normal individuals and in patients with glaucoma or ocular hypertension (OHT). METHODS: A comprehen…

BACKGROUND: Rituximab, a monoclonal anti-CD20 antibody, in combination with chemotherapy improves overall survival compared to chemotherapy alone when used for induction therapy for patients with newly diagnosed or relapsed indolent lymphoma. Randomised controlled trials have demonstrated that maintenance treatment wit…

BACKGROUND: Apnoea is a breathing disorder marked by the absence of airflow at the nose or mouth. In children, risk factors include adenotonsillar hypertrophy, obesity, neuromuscular disorders and craniofacial anomalies. The most common treatment for obstructive sleep apnoea syndrome (OSAS) in childhood is adenotonsill…

BACKGROUND: Inhibitory control is a key component of executive function, influencing academic achievement, behavior, and long-term outcomes in children and adolescents. Physical activity (PA) has been identified as a potential intervention to improve inhibitory control, but the optimal type and dosage remain uncertain.…

Sleep disorders, particularly chronic insomnia (), represent an escalating global public health challenge associated with extensive neuropsychological and metabolic morbidities. While conventional pharmacotherapy provides immediate symptomatic relief, concerns regarding dependency, tolerance, and altered sleep architec…

BACKGROUND: Despite successful reduction of bacterial load and clinical inflammation following periodontal therapy, high recurrence rates indicate that prior infections induce lasting host alterations, maintaining latent disease susceptibility AIM: This review elucidates the biological basis of periodontal recalcitranc…

INTRODUCTION: Periodontitis, a chronic inflammatory disease, may necessitate surgical intervention when non-surgical methods are ineffective. This systematic review and network meta-analysis investigates the efficacy and safety of various laser types in periodontal flap microsurgery, consolidating clinical trial result…

Automation software has improved accuracy, efficiency, and reproducibility in transthoracic echocardiography, but its role in transesophageal echocardiography (TEE) is less well established. Given rapid technological advances and heterogeneity among available tools, a comprehensive overview of current evidence is warra…

OBJECTIVE: This review aims to assess the association between the genetic polymorphisms and the occurrence, severity of signs and symptoms, and sex-specific presentation of temporomandibular disorder subtypes. INTRODUCTION: Temporomandibular disorders (TMDs) are multifaceted conditions that affect the temporomandibula…

Onychomycosis is a common nail disease that manifests with varying severity and frequency in specific patient populations, warranting a personalized treatment approach. Novel topical antifungals, such as efinaconazole 10% approved for use in North America and Japan, offer a safe treatment option for many of these patie…