Paternal body mass index and offspring DNA methylation: findings from the PACE consortium.
Sharp Gemma C, Alfano Rossella, Ghantous Akram, +8 more·International journal of epidemiology
BACKGROUND: Accumulating evidence links paternal adiposity in the periconceptional period to offspring health outcomes. DNA methylation has been proposed as a mediating mechanism, but very few studies have explored this possibility in humans. METHODS: In the Pregnancy And Childhood Epigenetics (PACE) consortium, we co…