98,324 papers found

The 13th annual report from The Society of Thoracic Surgeons (STS) Interagency Registry for Mechanically Assisted Circulatory Support (Intermacs) highlights outcomes for 27,314 patients receiving continuous-flow durable left ventricular assist devices (LVAD) during the last decade (2012-2021). In 2021, 2464 primary LVA…

PURPOSE: To explore whether epidemiological shifts regarding reproduction and pregnancy have influenced the spectrum of indications for late termination of singleton pregnancies (TOP) above 17 weeks of gestation and to evaluate temporal changes in maternal demographics and fetal indications over the last 16 y…

PURPOSE: The spectrum of intraocular and systemic findings in patients with ocular syphilis is described. Persistent visual dysfunction and structural abnormality, in spite of targeted antibiotic therapy, were identified and analysed. METHODS: Patients with ocular syphilis who were treated at University Hospital Zuric…

BACKGROUND: Unintended pregnancy is an important reproductive health problem in both developed and developing countries and is most prominent in low-middle income countries. In the Democratic Republic of the Congo, the total fertility rate is high at 5.9 births per women, and a mother's probabily of dying at an age bet…

BACKGROUND: Peritoneal carcinomatosis is an increasingly common finding in gastric carcinoma. Previously, patients were treated as terminal, and median survival was poor. The use of cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) in this context is still highly debatable. OBJECTIVE: T…

BACKGROUND: Minute ventilation (V · E) during walking has been shown to be higher in older individuals than in young individuals, but the mechanisms underlying the higher ventilatory response is unclear. Central command and peripheral neural reflex are important neural control mechanisms underlying ventilatory res…

OBJECTIVES: According to the Swiss Federal Commission for HIV/AIDS, HIV-infected patients on successful antiretroviral treatment have a negligible risk of transmitting HIV sexually. We estimated the risk that patients considered to have an undetectable viral load (VL) are actually viraemic. METHODS: A Danish, populati…

OBJECTIVE: To investigate effectiveness of long-term treatment of myasthenia gravis (MG) with intravenous immunoglobulin (IVIG). BACKGROUND: There are no definitive studies showing effectiveness of IVIG therapy in long-term treatment of MG. Most studies have investigated the acute treatment of MG with IVIG. We describ…

BACKGROUND:  Literature on the prevalence of musculoskeletal disorders (MSD), work ability, and associated factors among dentists is limited. Therefore, this study aimed to determine the prevalence of MSD, work ability, and associated factors among dentists in Kerala, India. METHODS:  This cross-sectional st…

Models of random phylogenetic networks have been used since the inception of the field, but the introduction and rigorous study of mathematically tractable models is a much more recent topic that has gained momentum in the last 5 years. This manuscript discusses some recent developments in the field through a selection…

Skin grafting in nasal reconstruction, long used by dermatologists, can provide superior results and can well be the "go to" procedure for nasal reconstruction. The upper two-thirds of the nose is composed of both flattened, featureless and often thin skin that is well recreated with defect-only full-thickness grafting…

The last several years have witnessed the accumulation of evidence suggesting that the Kraepelinian binary system of classification of the psychoses does not capture their true nature, as Kraepelin himself had cautioned in his late years. The long-awaited new edition of the APA's Diagnostic and Statistical Manual will…

Colorectal cancer is the most frequent neoplasm in Western countries and the second leading cause of cancer death. However, this form of cancer may benefit from preventive measures, especially screening. Several cost-effective strategies are available: annual and biennial fecal occult blood testing, flexible sigmoidosc…

Tinnitus, or the phantom perception of sound, is one of the great unsolved problems of otology. It is present in all patients with hearing loss and, in approximately 5-10% of individuals, it has a significant impact on quality of life. Progress in the treatment of tinnitus has been limited by a lack of animal models th…

It is generally accepted that menopausal symptoms can be controlled by HRT. As additional (putative) benefits of HRT were discovered, it was claimed that such uses were also important. Soon, trials were instituted to test these assertions, some of them quite large and projected to last a long time (> or = 5 years). The…

A 21 years old male suffered from repeated furunculosis in different regions of the body over the last two years. This coincided with the start of professional activities in hospital surroundings. The purulent secretions all showed growth of Staphylococcus aureus. All laboratory tests were normal except for a decrease…

Hospitals are the sick component of the healthcare sector in many European countries and have been so for a long time. As long as 10 years ago, economists noted the urgent need for hospitals to restructure. During the last 5 years, there has been a surge in hospital mergers, closures and revamping throughout France. Ye…

Hypospadias is a common congenital anomaly in male newborns. The incidence is about one in 300 live male births. In the U.S., about 6000 boys with hypospadias are born each year. For this study, we collected 117 recent (with the last 5 years) cases (88 fresh and 29 referred) who received an operation in our department.…

Asthma has been described primarily as an inflammatory process only in the last 5 to 10 years. Previously, it was thought of primarily as a disease of nerves and smooth muscle. This inflammatory process is now considered to be an immunologically initiated, mediator-driven event. The observation that asthma is associate…

Epidemiologic characteristics of tetanus in Voivodina were analyzed on the basis of reported cases of sickness or death, during the period from 1962 to 1991, and epidemiologic investigation on 35 sick persons suffering from tetanus during the last 5 years. By compulsory immunization against tetanus this disease is prac…