2,693 papers found

PURPOSE: Needle-free jet injection has to some extent improved the quality of life of patients with diabetes, but it has not been widely used. Therefore, we analyzed articles, clinical trials, and patents of needle-free insulin injection to (1) perform a systematic and comprehensive analysis of scientific research and…

INTRODUCTION: While evaluations of indoor smoke-free legislation have demonstrated major public health benefits among adults, their impact on the smoking behavior of young people remains unclear. Therefore, we performed a systematic review of the association between smoke-free legislation in hospitality venues and smok…

BACKGROUND: The nursing shortage is driven, in part, by the critical shortage of nursing faculty. Consequently, qualified potential nursing students are being turned away from nursing schools each year. The preeminent issue influencing the United States nurse faculty workforce shortage is salary; financial compensation…

OBJECTIVES: The purpose of this study is to review a single-institutional experience gained over one decade, to assess late neuropsychological outcome in patients as well as to determine Norwood operation risk factors that are related to patient and procedure and influence these results. BACKGROUND: The reports of fir…

In addition to standard anterior temporal lobectomy (ATL), subtemporal selective amygdalohippocampectomy (sSAH) is also a common technique for the treatment of medically intractable mesial temporal lobe epilepsy (MTLE). We conducted a systematic literature review to determine the seizure and neuropsychological outcomes…

Atopic dermatitis (AD) is well-recognized as a very common chronic and relapsing pruritic skin disorder affecting both children and adults worldwide. The adverse effects on the quality of life of affected individuals and their families is well-established. The pathophysiology of AD is complex, leading to interindividua…

OBJECTIVE: To review the available evidence for home smoking restrictions as a useful tool in the prevention of youth smoking and to make recommendations for further research. METHODS: A PubMed search (1 January 1990 to 26 January 2010) identified studies involving youth ≤18 years using extensive criteria. In a…

BACKGROUND: It is a challenge to dispatch Emergency medical Services (EMS) appropriately with limited resources and maintaining patient safety; this requires accurate dispatching systems. The objective of the current systematic review was to examine the evidence, according to GRADE, for medical dispatching systems to a…

BACKGROUND: Diagnostic neurovascular imaging data are important in stroke research, but obtaining these data typically requires laborious manual chart reviews. OBJECTIVE: We aimed to determine the accuracy of a natural language processing (NLP) approach to extract information on the presence and location of vascular o…

OBJECTIVES: To report on what doctors at very different levels of seniority wrote, in their own words, about their concerns about the European Working Time Directive (EWTD) and its implementation in the National Health Service (NHS). DESIGN: All medical school graduates from 1993, 2005 and 2009 were surveyed by post a…

OBJECTIVE: To conduct a systematic literature review of cost-of-illness studies and economic evaluations for diabetic patients with comorbid depression. METHODS: Systematic literature search in PubMed and NHS EED in March 2011, complemented by a bibliographic search within all eligible articles. RESULTS: The search p…

INTRODUCTION: Recurrent head and neck cancer (HNC) after radiotherapy presents a reconstructive challenge. Whether pedicled or free flap reconstruction leads to better outcomes remains unclear. This review aims to assess the outcomes of pedicled and free flap reconstruction in patients with recurrent HNC after radiothe…

BACKGROUND: The aim of the study is to perform a morphological analysis of certain lysosomal enzymes and parenchymal alterations during warm ischemia in the pig liver. METHODS: Standard hepatectomies were performed in a set of 24 pigs. Intra-operative intravenous (portal vein) Pentoxiphylline and hydroxyl radical scav…

OBJECTIVE: Seizure-frequency information is critical for epilepsy research and clinical decision-making, yet it is often documented in highly variable free-text neurology clinic letters that are difficult to share and annotate at scale. This study focused on adult epilepsy clinic letters from patients aged 18 years or…

BACKGROUND: Nipple-areolar tattooing is well accepted as part of breast reconstruction, but the clinical data on its safety and patient satisfaction after the procedure are insufficient. We aimed to evaluate the complications of and patient satisfaction after nipple-areola tattooing in Japanese post-mastectomy breast r…

Longitudinal birth cohort research provides a glimpse into the biological and social trajectories of a cohort of people, which helps us to better understand how to improve health and social outcomes. While qualitative longitudinal, ethnographic, and other qualitative research methods are increasingly used to capture co…

The prevalence of suicide attempts and suicidal ideation among university students is a global concern. Cultural values, social determinants, religion, and especially growing stress all play an important role in this. This systematic review aimed to identify potential protective and risk factors thought to be associate…

BACKGROUND: Forty percent of women will experience prolapse in their lifetime. Vaginal pessaries are considered the first line of treatment in selected patients. Major complications of vaginal pessaries rarely occur. METHODS: PubMed and Embase were searched from 1961 to 2022 for major complications of vaginal pessarie…

OBJECTIVES: To promote resource stewardship in thyroid hormone testing at a pediatric tertiary care hospital. STUDY DESIGN: Quality improvement approaches generated 3 change ideas that were implemented simultaneously in the hospital electronic medical record: (1) a reflex free thyroxine (fT4), whereby fT4 is automatic…

This study is a systematic review of prospective randomised control studies comparing ultrasound-guided steroid injection of the subacromial space with anatomic landmark-guided injection in the treatment of subacromial impingement to determine if there is any difference in pain relief and functional outcome. Mesh terms…