Sample-size estimation: a sensitivity analysis in the context of a clinical trial for treatment of mild hypertension.
Laird N M, Weinstein M C, Stason W B·American journal of epidemiology
The effectiveness of treatment for mild hypertension (diastolic pressures of 85 to 105 mm Hg) has not been conclusively demonstrated. Both the costs of a carefully designed clinical trial and the likelihood that it will produce definitive answers will depend importantly on the sample size. This paper presents sample-si…