42,360 papers found

BACKGROUND: A crown-root fracture is defined as a fracture involving enamel, dentin, and cementum. The possibility of saving and reconstructing teeth with such fractures has increasingly become a viable alternative to extraction and prosthetic therapy. One such treatment option available is surgical extrusion. OBJECTI…

Substantial evidence indicates that stress can precipitate or worsen symptoms of inflammation in general and more specifically in multiple sclerosis (MS), a demyelinating, autoimmune disease characterized by inflammation of the central nervous system (CNS). However, the mechanism of how stress affects MS is not well un…

OBJECTIVE: Catastrophizing is an exaggerated negative evaluation and attention to specific symptoms such as pain or fatigue. A number of studies consistently support the significant role of catastrophizing in pain. However, the role of catastrophizing in fatigue is less frequently investigated. This article provides a…

AIM: identify and analyze in the literature the evidence of randomized controlled trials on care related to the suctioning of endotracheal secretions in intubated, critically ill adult patients undergoing mechanical ventilation. METHOD: the search was conducted in the PubMed, EMBASE, CENTRAL, CINAHL and LILACS databas…

INTRODUCTION: Obesity is a risk factor for chronic diseases and premature mortality, but the extent of these associations among the elderly is under debate. The aim of this systematic literature review (SR) is to collate and critically assess the available information of the impact of obesity on mortality in the elderl…

OBJECTIVE: To evaluate the effect of surgical treatment between correction and non-correction surgery for degenerative lumbar scoliosis by systematic review method. MATERIAL AND METHOD: The database inclusions were PubMed (January 1, 1960 to March 31, 2009), EMBASE (January 1, 1985 to March 31, 2009), The Cochrane Cen…

Colorectal cancer is the third most common cancer with a 5-year survival rate of 30-65%. A portion of the interpatient variability in its clinical outcome is attributed to inherited and somatic genetic factors. Although numerous research articles have investigated these factors in colorectal cancer, there has not been…

AIM: To review the literature on lithotomy-related neurovascular complications (LRNVC) of the lower limbs after colorectal surgery. METHOD: Electronic databases were searched for relevant articles, including Medline, EMBASE, Pubmed, CENTRAL and CINHL. RESULTS: LRNVC after prolonged lithotomy position during colorecta…

The discovery of novel biomarkers is a crucial goal in translational biomedical research. A complete and accurate reporting of biomarker studies, including quantitative prediction models, is fundamental to improve research quality and facilitate their potential incorporation into clinical practice. This paper reviews k…

BACKGROUND: Anorexia nervosa is a complex condition that brings great challenges at each stage of treatment. This study aims to organize the body of information available in qualitative studies about the treatment of anorexia nervosa through a systematic literature review and metasynthesis. METHODS: Searches were carr…

Multiple sclerosis (MS) is a chronic, unpredictable disease of the central nervous system without a known cure. Because of this, people with MS often seek complementary and alternative medicines (CAM) to manage their disease symptoms. The goal of this review article was to describe the use of CAM by individuals diagnos…

INTRODUCTION: Intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) are increasingly recognised to be a contributing cause of organ dysfunction and mortality in critically ill patients. The number of publications describing and researching this phenomenon is increasing exponentially but there are…

BACKGROUND: Kinesio Taping (KT) is commonly used in musculoskeletal disorders and rehabilitation practice, but its role in spinal cord injury (SCI) has received little scientific attention. OBJECTIVE: This scoping review aimed to map the existing literature on KT use in persons with SCI, describing how it has been app…

The gut-brain axis has emerged as a critical pathway influencing central nervous system (CNS) tumor biology through complex microbiome-mediated mechanisms. Understanding these interactions is essential for developing novel therapeutic strategies and biomarkers for CNS tumors. To systematically review and meta-analyze c…

UNLABELLED: Collective use center is an organization or structural unit with unique resource providing access to this resource for internal and third-party users. Collective use centers are a relatively new phenomenon in bioresource collections, especially collections of human biological material due to some ethical an…

BACKGROUND: Primary central nervous system lymphomas may present as diffuse, nonenhancing infiltrative lesions. This rare variant is termed lymphomatosis cerebri (LC). We did a systematic review and analysis of the literature, adding our own cases, to better characterize LC in order to improve early diagnosis and treat…

BACKGROUND AND OBJECTIVES: The gut microbiome is a key determinant of overall health, impacting numerous bodily functions, such as those of the endocrine glands. The effect of the microbiota on thyroid function has become a matter of interest, more so since the revelation of the possible link between intestinal disease…

OBJECTIVE: Funding bodies such as Canada's Tri-Agency have implemented requirements for grant recipients to encourage improved research data management (RDM) practices and data sharing. Consequently, RDM and data sharing have become a higher priority for researchers and stakeholders supporting the research process, inc…

Arrhythmia is an important cause of cardiovascular disease deaths and a serious threat to human health, but the current means of identification are limited. Biomarkers, with the advantages of easy access and rapid detection, have shown significant value in arrhythmia risk prediction, precision diagnosis, and prognosis…

Selenium (Se) is an essential micronutrient with multiple and complex effects on human health, including potent antioxidant, anti-inflammatory, and antiviral properties. Cardiovascular disease (CVD) and its most severe complications are the leading causes of mortality and disability worldwide. Considering the fact that…