382,120 papers found

BACKGROUND: The share of elderly patients undergoing emergency surgery is constantly increasing. Their postoperative outcome remains poor, even if surgery itself is survived in the short or medium term. OBJECTIVES: Important aspects of anesthesiologic care for older emergency patients based upon recent literature and…

ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION: The effect of dental pulp capping materials on hard-tissue barrier formation. Didilescu AC, Cristache CM, Andrei M, Voicu G, Perlea P. J Am Dent Assoc 2018; 149 (10):903 - 17. SOURCE OF FUNDING: None. TYPE OF STUDY/DESIGN: Systematic review and meta-analysis of data.

ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION: Bone density and clinical periodontal attachment in postmenopausal women. Penoni DC, Fidalgo TKS, Torres SR, Varela VM, Masterson D, Leão ATT, Maia LC. J Dent Res 2017; 96(3):261-9.s SOURCE OF FUNDING: Information not available. TYPE OF STUDY/DESIGN: Systematic review…

The Cochrane Collaboration has developed guidelines for the conduct of meta-analyses and systematic reviews. When applied to well-conducted short-duration randomized controlled trials, meta-analysis can be informative, but seldom in prolonged trials, because of "unblinding", non-adherence, losses to follow-up, and "cro…

In a meta-analysis of predominantly observational data, blood transfusion was independently associated with adverse outcomes in patients with myocardial infarction. These findings are consistent with previously published research, but clinical application of these data is hindered by the lack of prospective, randomized…

Systematic reviews in the form of overviews or meta-analyses offer a solution for busy practitioners who have difficulty keeping abreast of current literature. Because systematic reviews can condense numerous studies into reliable and valid summaries of the best available evidence for a specific clinical problem, they…

Effect size is used in single studies to complement inferential statistical analysis. It also is used to compare and synthesize data across studies in meta-analysis. Effect size provides information about clinical importance of differences found in research observations. For researchers, effect size is useful in establ…

Changes of causal inference concepts in medicine, especially those having to do with chronic diseases, were reviewed. The review is divided into five sections. First, several articles on the increased academic acceptance of observational research are cited. Second, the definitions of confounder and effect modifier conc…

General considerations about meta-analysis and the different steps of this technique are successively discussed: definition of the main objective, identification of the outcome, description of the retrieval and selection of trials, description of the statistical analysis and interpretation of the results. Advantages an…

Prior literature suggested an association among alcoholism, drug abuse, and antisocial personality disorder. A meta-analysis of inferential studies bearing on these associations was performed on 40 studies. Results demonstrated that each diagnosis in the triad had a significant positive association with each of the oth…