44,697 papers found

OBJECTIVE: To retrospectively analyze the effects of different treatments on cognitive functioning, anxiety, and depression in patients with primary central nervous system lymphoma (PCNSL). METHODS: A comprehensive literature search was conducted in multiple databases including the Cochrane Library, CINAHL, PubMed, We…

Antibiotics are considered the backbone of rosacea management, especially for controlling inflammatory papules and pustules. We aim to evaluate the efficacy and safety of varied prescriptions and doses of antibiotics in treating rosacea by network meta-analysis.In this study, we compared all available randomized contro…

BACKGROUND: Clinical and preclinical studies suggested that certain mutagens occurring as a reaction of creatine, amino acids, and sugar during the high temperature of cooking meat are involved in the pathogenesis of human cancer. Here we conducted a systematic review and meta-analysis to examine whether meat mutagens…

OBJECTIVE: To synthesize the evidence for incidence, pathophysiology, etiology, and protocol-based management of hyperammonemia in lung transplant patients. BACKGROUND: Elevated ammonia levels are toxic to the brain, and hyperammonemia results in a potentially fatal complication for lung transplant recipients. The hal…

BACKGROUND: Despite the importance of fall prevention among older adults, limited research exists on interventions tailored to rapidly growing Hispanic/Latino populations in the United States. This protocol paper outlines the rationale and methods for conducting a scoping review to address this knowledge gap. METHODS…

Vitamin D deficiency is known to be common in the general population and has been linked to all-cause mortality. The classically recognized role of vitamin D is its involvement in calcium and phosphorous homeostasis and bone health. Recent evidence suggests that vitamin D may also play a role in other nonskeletal proce…

Depression is a prevalent and disabling disease influenced by genetic, immunological, and environmental factors. Although conventional treatments are effective, they face limitations such as treatment resistance and side effects. Monoterpenes, components of essential oils, exhibit diverse pharmacological activities, in…

Enhanced Recovery After Surgery (ERAS) protocols constitute evidence-based intervention pathways prepared to decrease surgical stress, maintain physiological function, and improve recovery. This study aimed to systematically review the ERAS effect after primary total hip arthroplasty (THA) or total knee arthroplasty (T…

RATIONALE: The use of immune checkpoint inhibitors (ICIs) has greatly improved the outcomes of cancer. However, ICI-induced immune-related adverse events have been reported, among which neurological immune-related adverse events are rare but potentially life-threatening. To analyze the characteristics of ICI-induced in…

BACKGROUND: Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is an inflammatory demyelinating disease of the central nervous system with a serious, debilitating presentation, including residual disability after relapses. OBJECTIVES: To evaluate the economic impacts of MOGAD and analogous conditi…

: Acute kidney injury (AKI) is a syndrome characterized by impaired kidney function, which is associated with reduced survival and increased morbidity. Central venous pressure (CVP) is a widely used hemodynamic parameter for assessing the volume status of patients and evaluating their response to fluid resuscitation. T…

OBJECTIVE: Traumatic Brain Injury (TBI) often leads to cognitive impairments, particularly regarding working memory (WM). This meta-analysis aims to examine the impact of TBI on WM, taking into account moderating factors which has received little attention in previous research, such as severity of injury, the different…

INTRODUCTION: Recent advances in tumor visualization have improved the extent of resection (EOR) of primary and secondary tumors of the central nervous system, while limiting the morbidity and mortality of the surgery. One area of recent interest has been the use of intraoperative fluorophores for tumor visualization s…

BACKGROUND: Both midline catheters (MCs) and peripherally inserted central catheters (PICCs) can cause catheter-related bloodstream infection (CRBSI), but the prevalence associated with each is not clear. OBJECTIVE: To compare the risk of CRBSI between MCs and PICCs with a meta-analysis. METHODS: The Web of Science C…

The purpose of this study was to systematically search the literature and analyze evidence from randomized controlled trials (RCTs) comparing tolvaptan with conventional diuretics for postoperative fluid management in cardiac surgery patients. An electronic search of PubMed, Scopus, BioMed Central, CENTRAL (Cochrane Ce…

INTRODUCTION: Vaccination against varicella rapidly reduces disease incidence, resulting in reductions in both individual burden and societal costs. Despite these benefits, there is no standardization of varicella immunization policies in Europe, including countries in Central and Eastern Europe (CEE). AREAS COVERED:…

IMPORTANCE: Children with neurodevelopmental disorders have a higher prevalence of sleep disturbances. Currently there is variation in the use of melatonin; hence, an up-to-date systematic review is indicated to summarise the current available evidence. OBJECTIVE: To determine the efficacy and safety of melatonin as t…

BACKGROUND: Sudden infant death syndrome (SIDS) has been most recently defined as the sudden unexpected death of an infant less than one year of age, with onset of the fatal episode apparently occurring during sleep, that remains unexplained after a thorough investigation, including the performance of a complete autops…

INTRODUCTION: Randomised clinical trials (RCTs) have been used to compare and evaluate different types of mesh fixation usually employed to repair open inguinal hernia. However, there is no consensus among surgeons on the best type of mesh fixation method to obtain optimal results. The choice often depends on surgeons'…

BACKGROUND/PURPOSE: The aim of this study was to review evidence-based literature addressing pertinent questions about venous thromboembolism (VTE) after traumatic injury in children. METHODS: Data were obtained from English-language articles identified through Pubmed published from 1995 until November 2012, and from…