5,085,241 papers found

BACKGROUND: Among the elderly, who are often exposed to polypharmacy, explicit deprescribing tools offer clear, validated guidelines for safely reducing medications. However, the effectiveness of these tools varies across healthcare settings and populations. In India, unique sociocultural and healthcare challenges dema…

BACKGROUND: Studies assessing the nutritional quality of food provided to the homeless population show deficiencies in micronutrients and excess fat, sugar, and salt. The availability of cheap, energy-dense and nutrient-poor food has changed the profile of people living with homelessness from primarily underweight to o…

INTRODUCTION: There are an increasing number of people living with and beyond cancer, whose experience is further complicated by additional long-term health conditions in the context of an ageing population. The supportive care needs of this growing patient group should be recognised and addressed. There is a need to e…

BACKGROUND: Systematic reviews attempt to gather all available evidence. Controversy exists regarding effort and benefit of including study results presented at conferences only. We recently published a Cochrane network meta-analysis (NMA) including 585 randomized controlled trials comparing drugs for prevention of pos…

Evidence in clinical research is accumulating and scientific publications have increased exponentially in the last decade across all disciplines. Available information should be critically assessed. Here, we focus on umbrella reviews, an approach that systematically collects and evaluates information from multiple syst…

ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION: Short-term and long-term effectiveness of powered toothbrushes in promoting periodontal health during orthodontic treatment: A systematic review and meta-analysis. Al Makhmari SA, Kaklamanos EG, Athanasiou AE. Am J Orthod Dentofacial Orthop 2017;152(6):753-66.e7. SOURCE OF…

INTRODUCTION: Sustainable procurement (SP) has emerged as an integral part of national and global efforts to address sustainable development challenges and the growing impact of climate change on human health, especially in resource-constrained health systems such as sub-Saharan Africa (SSA). We are conducting a scopin…

INTRODUCTION: Over the last two decades, patient portals have emerged as a noticeable eHealth strategy. To date, research on patient portals has been rapidly increasing. Our umbrella review aims to provide a meta-level synthesis to make sense of the evidence on patient portals from published systematic reviews (SRs).…

BACKGROUND: Although dual independent review of search results by two reviewers is generally recommended for systematic reviews, there are not consistent recommendations regarding the timing of the use of the second reviewer. This study compared the use of a complete dual review approach, with two reviewers in both the…

BACKGROUND: Rapid reviews are increasingly used to replace/complement systematic reviews to support evidence-based decision-making. Little is known about how this expedited process affects results. OBJECTIVES: To assess differences between rapid and systematic review approaches for a case study of test accuracy of suc…

BACKGROUND: The validity of a review depends on its methodologic quality. OBJECTIVE: To determine the methodologic quality of recently published review articles. DESIGN: Critical appraisal. SETTING: All reviews of clinical topics published in six general medical journals in 1996. MEASUREMENTS: Explicit criteria tha…

Reviews of published scientific literature are a valuable resource that can underline best practices in medicine and clarify clinical controversies. Among the various types of reviews, the systematic review of the literature is ranked as the most rigorous since it is a high-level summary of existing evidence focused on…

Assessment of applicability is an essential part of the systematic review process. In the context of systematic reviews of the effects of interventions, applicability is an assessment of whether the findings of a review can be applied in a particular context or population. For more complex interventions, assessing appl…

INTRODUCTION: Past attempts to reduce inequalities in primary care have been met with mixed success. For initiatives to reduce inequalities, it is essential that they identify the most vulnerable groups in society to prevent any future exacerbation of inequalities. Intersectionality theory provides a framework to ident…

INTRODUCTION: The aim of the protocol is to present the methodology of a scoping review that aims to synthesise up-to-date evidence on adolescent undernutrition in South Asia. METHODS AND ANALYSIS: The proposed scoping review will be guided by Arksey and O'Malley's framework and the Joanna Briggs Institute Reviewers'…

The recent interest in systematic review methods in bioethics has highlighted the need for greater transparency in all literature review processes undertaken in bioethics projects. In this article, I articulate features of a good bioethics literature review that does not aim to be systematic, but rather to capture and…