2,530 papers found

BACKGROUND: The effectiveness of pedicled muscle flaps versus microsurgical free flaps in patients with diabetes mellitus for complex foot and ankle reconstruction has not been well defined. METHODS: The Georgetown Wound Registry identified all patients who underwent pedicled muscle flap or free flap reconstruction fr…

PURPOSE: Defects resulting from open resection of anterior skull base neoplasms are difficult to reconstruct. Our objective was to review the literature and describe an evidence-based algorithm that can guide surgeons reconstructing anterior skull base defects. METHODS: A research librarian designed database search st…

We present a novel, highly versatile, and self-referenced arrival time monitor for measuring the femtosecond time delay between a hard X-ray pulse from a free-electron laser and an optical laser pulse, measured directly on the same sample used for pump-probe experiments. Two chirped and picosecond long optical supercon…

BACKGROUND: The COVID-19 pandemic has affected the entire world tremendously. Particularly during the second wave in India, a dangerous complication followed in the form of COVID-19-associated mucormycosis. On June 7th, 2021, the Indian Union Health Minister stated that 28,252 cases of mucormycosis were reported from 2…

INTRODUCTION: Nutritional Risk Screening-2002 (NRS-2002) has been recently used to evaluate the nutritional status of patients according to the recommendation of ESPEN. In this prospective study, we aimed to find the effectiveness of NRS-2002 on preoperative patients who were candidates for elective procedure at a gene…

UNLABELLED: The aim of the study was to determine whether the treatment outcome differs for males and females in the mixed-gender methadone maintenance program. A prospective non-randomized study was performed to evaluate the efficiency of the treatment over a period of 6 months. In this study, 91 patients (60 male and…

The total Hcy, methionine, vitamin B12, folic acid and vitamin B6 blood concentrations were measured in apparently healthy adult subjects aged 20-30 years with three types of nutrition - 52 normal weight subjects of general population on traditional mixed diet (non-vegetarians), 52 normal weight vegetarians and 24 over…

Complementary and Alternative Medicine (CAM) is a therapeutic option currently used by autistic people with continued interest and uptake. There remains limited evidence regarding the efficacy of CAM use in autism. The aim of this systematic review is to comprehensively review published clinical trials to explore the e…

OBJECTIVE: To systematically identify, appraise, and examine evidence regarding the effects of therapeutic tape on pain and function in individuals with lateral epicondylalgia (LE). METHODS: Five electronic databases were systematically searched up to March 2018. Full-text, peer-reviewed, English-language studies were…

OBJECTIVE: The objective of this review is to evaluate the safety and efficacy of tafluprost, a fluoroprostaglandin receptor analog, for reduction of intraocular pressure in open angle glaucoma and ocular hypertension. METHODS: A search of published literature was performed on the PubMed database using the search term…

Blood pressure measuring represents a routine investigation in general medicine. In the last decades large studies have determined average blood pressure values all around the world. Large clinical trials have shown that blood pressure reduction irrespective of the used type of therapeutic intervention reduces mortalit…

PURPOSE: Recent data indicate that women with breast cancer receiving aromatase inhibitors (AIs) are at increase risk of osteoporosis. PATIENTS AND METHODS: We evaluated 263 patients in our study, 42 receiving AI (22 - Arimidex, 20 - Femara), 69 selective estrogen receptor modulater (SERM - Tamoxifen), in 72 the thera…

OBJECTIVE: The study was designed to identify any association between the sacral hiatus of the dry sacral bones with that of patients with low back pain (LBP). The knowledge of the sacral hiatus is important in caudal epidural block (CEB). METHODS: Three hundred forty three (183 male and 160 female) complete and undam…

BACKGROUND: Detecting uncertain and negative assertions is essential in most BioMedical Text Mining tasks where, in general, the aim is to derive factual knowledge from textual data. This article reports on a corpus annotation project that has produced a freely available resource for research on handling negation and u…

BACKGROUND: This study aims to assess the quality of four selected traumatic brain injuries management guidelines used mainly in the US and in Europe. METHODS: The instrument Appraisal of Guidelines Research & Evaluation was selected to provide a framework for guidelines appraisal. Four guidelines addressing a specifi…

Systematic Reviews (SRs) hold promise for implementing the 3Rs in animal sciences: they can retrieve available alternative models, help refining experiments, and identify insufficiencies, or an excess of, scientific knowledge on a particular topic. Unfortunately, SRs can be labour- and time-intensive, especially the re…

Percutaneous transhepatic gallbladder drainage (PTGBD) is considered a safe alternative to early cholecystectomy, especially in surgically high-risk patients with acute cholecystitis. Although randomized prospective controlled trials are lacking, data from most retrospective studies demonstrate that PTGBD is the most c…

OBJECTIVE: Authors retrospectively analyze a group of patients with symptomatic peripheral arterial occlusive disease (PAOD) who underwent an arterial reconstruction with a remote retrograde endarterectomy combined with intraoperative angiography and endovascular techniques as a hybrid procedure. RESULTS: During the y…

OBJECTIVE: Congenital vertical talus is a rare condition but a well-known cause of severe rigid flatfoot in children. The aim of this study was to evaluate the mid-term clinical and radiological results of one-stage surgical correction in children with congenital vertical talus. METHODS: Five feet in three children di…

UNLABELLED: Carpal tunnel syndrome (CTS) is the most common form of peripheral nerve entrapment. Electromyography with selected nerve conduction studies (NCS) is an accepted diagnostic tool in CTS patients. Ultrasonography presents a widely available and low cost investigation method and its position in CTS diagnostics…