11,527,449 papers found

If the purpose of a clinical study is not only to test the null hypothesis but also to estimate the magnitude of the treatment effect, the study design should ensure not only that the study will have adequate power but also that it will enable the researcher to report the relevant parameters with an appropriate level o…

BACKGROUND: The author is a professional doctorate student and full-time nurse in an education role in a UK NHS Trust. COVID-19 caused a major disruption to her research, which focused on nursing workforce development in primary care. She received ethical approval for the research in February 2020 and had just begun to…

Metabolic endotoxemia (ME) is characterized by a 2-3-fold increase in blood endotoxin levels and low-grade systemic inflammation without apparent infection. ME is usually accompanied by metabolic syndrome, characterized by central obesity and hyperlipidemia. According to numerous studies, ME may lead to functional brai…

Three studies considered the consequences of writing, talking, and thinking about significant events. In Studies 1 and 2, students wrote, talked into a tape recorder, or thought privately about their worst (N = 96) or happiest experience (N = 111) for 15 min each during 3 consecutive days. In Study 3 (N = 112), student…

Although transgender women have been included in HIV prevention pre-exposure prophylaxis studies, no pre-exposure prophylaxis study has focused exclusively on transgender persons. Drawing on the cardinal principles of ethics espoused in the Belmont Report, this work highlights, among other issues, that (1) the principl…

This study's objective is to examine the relationship between emotional demands and emotional social support at work, and the impact of resilience on health. A cross-sectional study of 156 firefighters was conducted. Descriptive analyses of the study's variables were performed, along with structural equation analysis a…

This study's main purpose was to examine the sensitivity estimates obtained from scaling and discrimination approaches for nociception assessment in healthy individuals. This investigation may inform future applications in diagnostic procedures for painful conditions. Models of psychophysical judgment based on those of…

The present study used a longitudinal correlational design to test whether variation in mothers' use of information-seeking and confirmation questions predicts variation in auxiliary and copula development in a sample of specific-language-disordered children. The study's confirmatory approach provides a sound empirical…

In attempting to draw bigger conclusions, researchers in psychology open their labs to more diverse groups of people. Yet even the most far-reaching theories must be tested with specific stimuli, materials, and methodology. To the extent that a study's stimuli are familiar beyond the lab to groups of people writ large,…

In longitudinal studies of pornography use, selective loss of participants who may be more vulnerable to the effects of pornography than their peers is a serious concern. To explore the potential for such selective dropout, we used data from two independent large-scale panel studies of adolescents' pornography use. Of…

OBJECTIVE: This study's objective was to analyze the effectiveness of educational and support programs for caregivers on reducing their burden. METHOD: The method used was a systematic review. The following were searched; MEDLINE, LILACS, Embase, Cochrane, Web of Science, SciELO and CINAHL. RESULTS: Seven randomized…

The primary goal of this research is to look into the impact of digital campaigns for environmental and economic incentives on environmental performance, with indoor and outdoor activities of households taken as mediating variables. PLS-SEM was used to evaluate and quantify the novel and complex model to meet the study…

Ophthalmoscopy performed for the early diagnosis of retinopathy of prematurity (ROP) is painful for preterm infants, thus necessitating interventions for minimizing pain. The present study aimed to establish the effectiveness of human milk, compared with sucrose, for pain relief in premature infants subjected to ophtha…

Can teaching students about brain plasticity improve their grades? A recent large, national experiment (Yeager et al.) found that a brief growth mindset intervention improved lower-achieving adolescents' grades by 0.10 points. Debate about interpreting the study's findings illustrates the need to consider effect h…

In the present study, S. mutans colony morphotypes has been investigated in salivary specimens obtained from 67 schoolchildren. Prevalence of these bacteria has been matched with DMFS in order to obtain information on cariogenicity of single morphotypes. Our data seems to suggest a correlation between total count of S.…

Emerging approaches that enable high-throughput analysis of the plasma proteome have been increasingly deployed in nephrology research. Kobayashi et al. provide a valuable addition to this literature, describing an untargeted proteomic analysis of diabetic kidney disease progression to end-stage kidney disease. Th…

The global shortage of human donor livers poses a formidable barrier to treating end-stage liver diseases and unresectable hepatic malignancies, leaving millions of patients without life-saving options each year. While genetically engineered pig-to-human xenotransplantation has achieved significant breakthroughs in car…

OBJECTIVES: It is estimated that NHS staff consist of over 200 different nationalities, with a reported 30.7% of doctors holding a nationality other than British. Despite this, international medical students represent 7.5% of all medical students studying in the UK and pay on average, 4-6 times more in tuition fees whe…