44,688 papers found

PURPOSE: This study aims to examine the distribution of narcotic drugs, psychotropic substances, and new psychoactive substances (NPS) among reported drug users in China. METHODS: This study searched peer-reviewed literature databases (i.e., CNKI and WANFANG for studies in Chinese, and Web of Science, PubMed, and Psyc…

This systematic review examines the impact of dietary fiber intake on insulin resistance in individuals with type 2 diabetes mellitus (T2DM). Given the global rise in T2DM prevalence and the central role of insulin resistance in its pathophysiology, there is an increasing emphasis on nonpharmacological interventions, s…

BACKGROUND: Cardiovascular disease (CVD) is the main cause of mortality in type 2 diabetes mellitus (T2DM) and detection of CVD risk is a key part of routine care. Slow walking speed is strongly correlated with CVD events in the general population. AIM: To see whether there is an association between reduced walking sp…

BACKGROUND: Renal ischemia-reperfusion injury (RIRI) represents a leading cause of acute kidney injury (AKI). Mitochondria, serving as the central organelles for cellular energy metabolism and signal transduction, play a pivotal role in the pathogenesis of RIRI. METHODS: Utilizing the three major academic databases-We…

INTRODUCTION: Cognitive impairment is a major complication of cerebrovascular diseases (CVDs), significantly affecting patients' quality of life. With limited approved pharmacological interventions, non-pharmacological approaches, such as remote ischemic conditioning (RIC), have emerged as potential therapeutic strateg…

BACKGROUND: Montelukast, a selective leukotriene receptor antagonist, is widely used in the treatment of bronchial asthma and allergic rhinitis (AR). Although it is a well-tolerated drug, there are reports of possible central nervous system side effects, including, for example, mood changes and suicidal thoughts. There…

Cerebral cavernous malformations (CCMs) are clusters of dilated, thin-walled vascular channels that pose significant neurological risks, particularly in pediatric patients. While stereotactic radiosurgery (SRS) has been explored as a non-invasive treatment modality, its safety and efficacy in children remain incomplete…

BACKGROUND: Over 70% of women and girls face heightened risks of sexual and reproductive health in conflict zones where reproductive health care is often neglected. This systematic review and meta-analysis aimed to estimate the epidemiological evidences of reproductive health risks of internal migrants in Ethiopia. ME…

BACKGROUND: The dietary supplement industry offers a wide range of orally consumed products that claim to combat skin photoaging, however, there is a lack of research on the proof of safety and effectiveness of dietary supplements in anti-skin photoaging. To further confirm their safety and efficacy, this article provi…

BACKGROUND: Faculty-student relationships are central to the academic and professional development of nursing students. This review aimed to systematically identify and synthesise existing evidence on the facilitators and barriers to quality faculty-nursing student relationships and their impact on student outcomes. M…

INTRODUCTION: Tension-type headache (TTH) is the most prevalent primary headache disorder worldwide, yet its neurobiological underpinnings remain partially understood. Neurotransmitter and neuropeptide alterations have been proposed as contributing factors, but evidence remains inconsistent. This systematic review aims…

PURPOSE: To estimate and compare the effect of two different nonreconstructive surgical techniques for treating periimplantitis. MATERIALS AND METHODS: An electronic search was performed in PubMed, Web of Science, Embase, Scopus, Ovid Medline, and the Cochrane Library of the Cochrane Collaboration (CENTRAL) for articl…

BACKGROUND/OBJECTIVES: Metabolomics provides insights into the biological underpinnings of disease development and treatment. This systematic review investigated the impact of acupuncture on metabolite levels and associated metabolic pathways using a metabolomic approach. METHODS: Five databases (i.e., PubMed, Embase,…

BACKGROUND: To explore aortic stiffness measured by carotid femoral-pulse wave velocity (cf-PWV) at different stages of normal glucose, prediabetes, and diabetes mellitus (DM). METHODS: The literature comparing aortic stiffness (AS) with cf-PWV between DM and non-DM samples was systematically retrieved from Pubmed, Ov…

OBJECTIVE: Systemic Therapy conceives mental health symptoms in the context of social systems. Previous meta-analyses on Systemic Therapy focused on symptoms. This meta-analysis aims to focus on family system functioning while including all types of outcomes. METHOD: We conducted a systematic literature research in mu…

This review aimed to comprehensively summarize the role of long non-coding RNA (lncRNA) in gliomas, the most common malignant tumors in the central nervous system, and explore their potential clinical applications. Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, a s…

PURPOSE: To update the literature on peripheral optics and vision following intraocular lens (IOLs) implantation. METHODS: We investigated how current IOLs influence peripheral visual function, peripheral optical quality, and visual perception and performance, in patients following cataract surgery. Peripheral vision…

Invasive lobular breast cancer (ILC) differs from invasive breast cancer of no special type in many ways. Evidence on treatment efficacy for ILC is, however, lacking. We studied the degree of documentation and representation of ILC in phase III/IV clinical trials for novel breast cancer treatments. Trials were identifi…

OBJECTIVES: Early diagnosis of infectious diseases remains a challenge. This study assessed the diagnostic value of mNGS in infections and explored the effect of various factors on the accuracy of mNGS. METHODS: An electronic article search of PubMed, Cochrane Library, and Embase was performed. A total of 85 papers we…

The goal of this systematic review was to collate and summarize the current literature on hemodialysis access outcomes in females, identify differences between females and men, and provide a foundation for future research. A systematic review of the English-language literature was conducted by searching PubMed and Goog…