42,360 papers found

OBJECTIVE: Evaluate content and educational delivery methods of preoperative education in total joint arthroplasties of the hip and knee (THA and TKA) addressing postoperative pain. DATA SOURCES: Systematic searches conducted on Biomed Central, BMJ.com, CINAHL, the Cochrane Library, NLM Central Gateway, OVID, ProQuest…

AIMS: To examine the literature pertaining to the diversion and misuse of pharmaceutical stimulants. METHODS: Relevant literature was identified through comprehensive MEDLINE, EMBASE and PubMed searches. RESULTS: The evidence to date suggests that the prevalence of diversion and misuse of pharmaceutical stimulants va…

BACKGROUND: The local and systemic humoral response after colorectal surgery is thought to affect postoperative recovery. It is commonly claimed that laparoscopic surgery elicits a diminished inflammatory response than equivalent open surgery. Despite these claims, the evidence is conflicting. Therefore, we aimed to sy…

BACKGROUND: Systematic review and meta-analysis to evaluate the effect of bevacizumab (Avastin) in diabetic macular edema (DME) METHODS: Pertinent publications were identified through systematic searches of PUBMED and Cochrane Central Register of Controlled Trials. Change in central subfield macular thickness (CSMT) in…

OBJECTIVES: To review the findings of structural and functional neuroimaging studies in attention-deficit hyperactivity disorder (ADHD), with a focus on abnormalities reported in brain regions that lie outside the frontostriatal circuitry, which is currently believed to play a central role in the pathophysiology of ADH…

BACKGROUND: Autism is a severe neurodevelopmental disorder known to have many different etiologies. In the last few years, significant progresses have been made in comprehending the causes of autism and their multiple impacts on the developing brain. This article aims to review the current understanding of the etiologi…

OBJECTIVE: The use of wearable motion-sensing technology offers important advantages over conventional methods for obtaining measures of physical activity and/or physical functioning in aged individuals. This review aims to identify the actual state of applying wearable systems for monitoring mobility-related activity…

PURPOSE: To describe adult attention-deficit/hyperactivity disorder (ADHD) in relation to gender-based differences in symptom expression with particular emphasis on disparities concerning women, psychiatric comorbidities that affect assessment and detection, and evidenced-based treatment approaches for nurse practition…

Drug development is complex and costly. Clinical trial participants take on risks, making it essential to maximize trial efficiency and maintain participant safety. Identifying periods of excessive burden during drug development can inform trial design, ensure patient benefit and prevent harm. This study aims to examin…

BACKGROUND: Total hip arthroplasty (THA) is the optimal surgical procedure for treating end-stage hip diseases. However, ipsilateral knee pain after THA, as a relatively insidious and not yet fully recognized complication, affects patient satisfaction and functional recovery. Its etiology is complex, involving the inte…

PURPOSE: This study aims to examine the distribution of narcotic drugs, psychotropic substances, and new psychoactive substances (NPS) among reported drug users in China. METHODS: This study searched peer-reviewed literature databases (i.e., CNKI and WANFANG for studies in Chinese, and Web of Science, PubMed, and Psyc…

Congenital abnormalities (CAs) are a major contributor to perinatal mortality and morbidity in India, particularly among abortuses and stillbirths. Despite the Ministry of Health and Family Welfare, India, introducing stillbirth surveillance guidelines, national data on the burden of CAs remain limited. This systematic…

This systematic review examines the impact of dietary fiber intake on insulin resistance in individuals with type 2 diabetes mellitus (T2DM). Given the global rise in T2DM prevalence and the central role of insulin resistance in its pathophysiology, there is an increasing emphasis on nonpharmacological interventions, s…

BACKGROUND: Cardiovascular disease (CVD) is the main cause of mortality in type 2 diabetes mellitus (T2DM) and detection of CVD risk is a key part of routine care. Slow walking speed is strongly correlated with CVD events in the general population. AIM: To see whether there is an association between reduced walking sp…

BACKGROUND: Renal ischemia-reperfusion injury (RIRI) represents a leading cause of acute kidney injury (AKI). Mitochondria, serving as the central organelles for cellular energy metabolism and signal transduction, play a pivotal role in the pathogenesis of RIRI. METHODS: Utilizing the three major academic databases-We…

INTRODUCTION: Cognitive impairment is a major complication of cerebrovascular diseases (CVDs), significantly affecting patients' quality of life. With limited approved pharmacological interventions, non-pharmacological approaches, such as remote ischemic conditioning (RIC), have emerged as potential therapeutic strateg…

BACKGROUND: Over 70% of women and girls face heightened risks of sexual and reproductive health in conflict zones where reproductive health care is often neglected. This systematic review and meta-analysis aimed to estimate the epidemiological evidences of reproductive health risks of internal migrants in Ethiopia. ME…

BACKGROUND: Tuberous Sclerosis Complex (TSC) is a multisystemic neurocutaneous disorder caused by pathogenic loss of function variants in the tumour suppressor genes TSC1 and TSC2. The resultant hamartomas confer significant medical risks by disruption of local tissues. Risk of mortality in TSC is known to be elevated,…

BACKGROUND: The dietary supplement industry offers a wide range of orally consumed products that claim to combat skin photoaging, however, there is a lack of research on the proof of safety and effectiveness of dietary supplements in anti-skin photoaging. To further confirm their safety and efficacy, this article provi…

BACKGROUND: Faculty-student relationships are central to the academic and professional development of nursing students. This review aimed to systematically identify and synthesise existing evidence on the facilitators and barriers to quality faculty-nursing student relationships and their impact on student outcomes. M…