5,085,026 papers found

INTRODUCTION: Suicide is one of the serious health problems among Indian adolescents. Adolescence helps with the transition of an individual into an adult, so it is important to understand the suicidal behavior of adolescents. Several studies have been carried out in different states in India on the suicidal behavior o…

INTRODUCTION: Cancer seriously threatens human health worldwide. Cancer cachexia is one of the life-threatening consequences that occurs commonly in patients with cancer, and severely worsens patient survival, prognosis and quality of life. Previous studies have demonstrated that cancer cachexia is closely related to d…

INTRODUCTION: There is widespread agreement that medical care without compassion cannot be patient-centred, but patients still routinely cite that they feel a lack of compassion in the care environment. There is a dearth of research on how compassion is experienced in a non-hospital setting such as a care home, not jus…

OBJECTIVES: An unknown number of randomized controlled trials (RCTs) have their treatment allocation subverted. If such trials are included in systematic reviews, biased results may be used to change policy. To assess whether a systematic review contains subverted trials, a meta-analysis of group differences regarding…

OBJECTIVES: Systematic reviews (SRs) are pivotal to evidence-based medicine. Structured tools exist to guide their reporting and appraisal, such as Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) and A Measurement Tool to Assess Systematic Reviews (AMSTAR). However, there are limited data on…

The recent narrative review, titled "The Involvement of Resolvins in Pathological Mechanisms of Periodontal Disease Associated with Type 2 Diabetes: A Narrative Review" [...].

The multiple sclerosis (MS) community read recently, with some surprise, the conclusions from a systematic review of the major therapeutic recombinant interferon trials in relapsing-remitting (RR)MS.1 The review stated that: 'their (recombinant interferons) clinical effect beyond 1 year is uncertain and new trials are…

State of the art is a legal concept that describes what was known as knowable by experts including manufacturer's state of knowledge about the potential hazards of their product(s) at a point in time. In 2004, Paustenbach et al. published a state-of-the-art review that describes the development of knowledge about asbes…

BACKGROUND: Maternal and perinatal quality collaboratives (M/PQCs) across nearly all U.S. states focus on improving health care and outcomes for birth parents and their infants. In the context of increases in maternal morbidity (MM) and severe maternal mortality (SMM) in the USA, M/PQCs increasingly focus on addressing…

OBJECTIVE: Systematic reviews are important in health care but are expensive to produce and maintain. The authors explore the use of automated transformations of Boolean queries to improve the identification of relevant studies for updates to systematic reviews. MATERIALS AND METHODS: A set of query transformations, i…

INTRODUCTION: German Digital Health Applications (DiGAs) are reimbursable, patient-facing digital interventions within the German healthcare system that must demonstrate positive healthcare effects. Outcome measurement in DiGA evaluations is influenced by both methodological considerations and feasibility requirements…

Stress is prevalent among health science students, particularly in rural settings where access to mental health resources is limited. Mobile health (mHealth) interventions offer a promising avenue for providing accessible support for stress management. This scoping review aims to identify existing mHealth interventions…

BACKGROUND: Cancer poses a major global health challenge, with rising incidence and mortality rates straining healthcare systems worldwide. Despite remarkable advances in cancer management modalities, the current approaches still fall short in overcoming drug resistance, tumour heterogeneity, toxicity and side effects.…

INTRODUCTION: The review described in this protocol will be the first critical realist review of the literature reporting on the impact of school-based mindfulness interventions on the mental wellbeing of pupils. Mindfulness interventions are increasingly being introduced into schools to promote children's (and teacher…

OBJECTIVE: The objective of this review is to describe the experience of loneliness and/or depression due to spousal separation when one or both spouses are admitted into a long-term care facility. INTRODUCTION: Loneliness and depression are important concerns for the health and well-being of older adults separated fr…