2,645 papers found

BACKGROUND: A diversity of endogenous and exogenous compounds have been demonstrated to cause proliferation of peroxisomes and variety of associated effects in rodents. The aim of our study was to see the effect of clofibrate on the enzymes associated with oxidative stress. METHODS: Male Wistar rats weighting 250-350…

BACKGROUND: Novel approaches that complement and go beyond evidence-based medicine are required in the domain of chronic diseases, given the growing incidence of such conditions on the worldwide population. A promising avenue is the secondary use of electronic health records (EHRs), where patient data are analyzed to c…

BACKGROUND: Human ABO blood group type and the antigenic secretor status are hypothesized to associate with oral diseases including oral cancer. Secretor status is the ability of individuals to secrete blood group antigens into body fluids. This study aimed to evaluate the secretor status of ABO antigens of saliva in p…

AIM: Metabolic syndrome (MetS) is a cluster of factors including obesity, hypertension, diabetes, hypercholesterolemia and hyperlipidaemia. It has been associated with an increased risk of colorectal neoplasia. This systematic review and meta-analysis assessed the association between MetS and (i) recurrence of adenomas…

OBJECTIVE: To assess the biomechanical performance of the application of polyethylene fiber and fiber-reinforced composite resins in direct restorations. MATERIALS AND METHODS: An electronic search was performed in Cochrane Library, Embase, and Pubmed on January 16th, 2025, with previously identified MeSH and free tex…

OBJECTIVES: Evidence-based therapeutic recommendations for removable dental prostheses are still lacking. The aim of the present study was a systematic review and meta-analysis of the survival rates of removable dentures in the moderately reduced dentition. MATERIALS AND METHODS: In 2014, a systematic literature searc…

Writing is an essential component of scientific activity. As such, it is necessary to develop strategies to provide equitable training opportunities for science writing. In order to provide learners with ways to improve their writing regardless of their language background and/or institutional and departmental environm…

Existing AI solutions-like the XGBoost tool by Li et al.-show potential for preoperative screening but rely on fixed questionnaires and opaque feature weighting. We introduce a hybrid framework that combines reasoning LLMs (OpenAI o3, DeepSeek R1, Google Gemini 2.5, Anthropic Claude 3.7 Sonnet) with specialty medical m…

OBJECTIVES: Automated understanding of clinical records is a challenging task involving various legal and technical difficulties. Clinical free text is inherently redundant, unstructured, and full of acronyms, abbreviations and domain-specific language which make it challenging to mine automatically. There is much effo…

OBJECTIVE: The use of machine learning technology to automate intellectual processes and boost clinical process efficiency in medicine has exploded in the past 5 years. Machine learning excels in automating pattern recognition and in adapting learned representations to new settings. Moreover, machine learning technique…

BACKGROUND: The objective of this systematic review was to identify the different surgical treatment modalities of severe trismus after head and neck squamous cell cancer treatment. METHODS: An electronic literature database search was conducted in Medline, Embase, Cochrane, Web of Science, and OpenGrey to determine a…

BACKGROUND: Systemic lupus erythematosus (SLE) is reported to be the most common rheumatological disorder associated with catatonia. To date, reports on catatonia manifestations in SLE patients are uncommon in published literature, which has often favored a fragmented vision. We performed a narrative review with the ai…

In 2022, the American Council for Graduate Medical Education (ACGME) recommended that core faculty (CF) in medical subspecialty fellowships receive at least 0.1 full-time equivalent (FTE) salary support, with plans to enforce compliance in July 2023. After early feedback raised concerns about potential unintended conse…

Nicotine-free electronic cigarettes (NFECs) are becoming increasingly popular, especially among youth and non-smokers, yet their effects on the gastrointestinal tract (GIT) remain poorly understood. This systematic review synthesizes available in vitro, in vivo, and limited human evidence on NFEC-associated changes in…

This review aims to provide a summary of the flowmeter devices used in microvascular surgery and assesses their contribution to improving the clinical outcomes of free tissue transfer. Flowmeters are widely accepted as the standard method of intraoperative assessment of the patency of coronary vascular anastomoses, pro…

The purpose of this systematic review was to calculate the 5-yr survival rates of all-ceramic zirconia-based fixed dental prostheses (FDPs) and to analyze technical and biological complications. An electronic literature search of MEDLINE (PubMed) was conducted independently by three reviewers to identify clinical studi…

Few studies have demonstrated an increased vulnerability to oxidative stress in autism. The results of previous studies have shown that endogenous antioxidant defence is insufficient, indicating that exogenous antioxidant could play a crucial role for oxidative stress prevention in autism. Plasma concentrations of vita…

PURPOSE: To assess the implant survival rate in mandibles reconstructed with free fibula flap after oral tumor resection after 1 year of prosthetic loading. A secondary objective was to compare immediate or delayed implant placement protocols in this population. MATERIALS AND METHODS: Electronic and manual searches we…

PURPOSE: To compare non-commercial DICOM toolkits for their de-identification ability in removing a patient's personal health information (PHI) from a DICOM header. MATERIALS AND METHODS: Ten DICOM toolkits were selected for de-identification tests. Tests were performed by using the system's default de-identification…

The significance of alignment scores of optimally aligned DNA sequences can be estimated through the score distribution of pairs of random sequences. It is necessary to obtain statistics for the relevant high-scoring tail of the distribution. For local alignments of iid drawn sequences it has already been shown that th…