The primary prevention of myocardial infarction.
Manson J E, Tosteson H, Ridker P M, +5 more·The New England journal of medicine
Abstract not available
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Manson J E, Tosteson H, Ridker P M, +5 more·The New England journal of medicine
Abstract not available
Wexler B E, Cicchetti D V·The Journal of nervous and mental disease
Multiple studies have demonstrated that individual psychotherapy, pharmacotherapy, and the two in combination are all effective treatments for depressed outpatients. However, the implications of these data for clinical practice have been incompletely considered, and the often drawn mistaken conclusion is that they supp…
Rindone J P, Sloane E P·The Annals of pharmacotherapy
OBJECTIVE: To review the risks, manifestations, and treatment of cyanide toxicity from nitroprusside therapy. DATA SOURCES: All English case reports identified in Index Medicus (MEDLINE) of cyanide intoxication related to nitroprusside from 1970 to the present were reviewed. In addition, literature regarding the incid…
Martens M G, Shailer L D·Advances in therapy
Available data from comparative trials involving 483 patients were analyzed to determine the rate of infectious morbidity following the use of absorbable staples versus traditional incision and suturing of the vaginal cuff in abdominal hysterectomy. Infections occurred in 24 of 268 (9%) patients who received absorbable…
van Duijn C M, Stijnen T, Hofman A·International journal of epidemiology
Studies of risk factors for Alzheimer's disease have been hampered by low statistical power. The data from 11 case-control studies were pooled and re-analysed to evaluate the evidence for the association of Alzheimer's disease with family history of dementia and related disorders, parental age, medical history, and env…
Palmieri G, Gridelli C, Airoma G, +4 more·Journal of chemotherapy (Florence, Italy)
Many clinical trials with 5-fluorouracil and leucovorin have been reported. This combination therapy seems to play an important role in untreated advanced colorectal cancer. In other neoplasms (gastric, head and neck, breast cancer) further studies are required.
Rassi Tiago N O, Amaral Dillan Cunha, Mund Eduardo, +3 more·Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics
OBJECTIVE: This network meta-analysis (NMA) of randomized controlled trials (RCTs) evaluates the long-term efficacy and feasibility of treatments for macular edema (ME) secondary to retinal vein occlusion (RVO). Comparisons between different alternatives remain unclear. METHODS: We used a Bayesian framework to perform…
Lei Xinming, He Kejie, Guo Yaqin, +2 more·European journal of gastroenterology & hepatology
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-associated death globally. Second-line therapies are crucial for improving survival and quality of life among individuals suffering from advanced HCC who have not responded to first-line therapies. This study sought to evaluate the safety and efficac…
Cai Ni, Zhu Shu-Ying, Huang Jin-Jing, +3 more·International urology and nephrology
OBJECTIVE: To compare the efficacy and safety of four immunosuppressive therapies, either alone or in combination, for primary membranous nephropathy through a network meta-analysis. METHODS: A literature search was conducted for randomized controlled trials (RCTs) of Cyclophosphamide (CTX), Cyclosporin (CsA), Tacroli…
Niederer Daniel, Fleckenstein Johannes, Floessel Philipp, +5 more·The Journal of orthopaedic and sports physical therapy
To estimate the comparative effectiveness of tailored exercise therapies in people with chronic, nonspecific low back pain.Systematic review with network meta-analysis.We searched PubMed, Cochrane Library, Web of Science, and Google Scholar from inception to August 27, 2024.Only randomized controlled trials (RCTs) stud…
Uralov Daniel, De Virgilio Armando, Canali Luca, +5 more·Head & neck
BACKGROUND: The role of postoperative antithrombotic therapy in microvascular free flap reconstruction remains controversial, with no consensus on the optimal regimen. METHODS: A systematic review and arm-based Bayesian network meta-analysis was conducted searching PubMed, Scopus, and Google Scholar databases. Aspirin…
Tan Xinyu, Wang Xiaokai, Li Xiangmin, +1 more·Prehospital emergency care
OBJECTIVES: The objective of this study was to evaluate video-assisted dispatcher cardiopulmonary resuscitation (V-DACPR) versus audio-assisted dispatcher CPR impacts on compression quality in simulated out-of-hospital cardiac arrest (OHCA) scenarios. METHODS: Network meta-analysis of randomized controlled trials (RCT…
Ribeiro Lucas Nascimento, Severino-Lazo Raisa, Vasconcelos Belmiro Cavalcanti do Egito, +2 more·Oral diseases
OBJECTIVES: A systematic review and network meta-analysis were conducted to address the following research question: "What is the most effective preventive treatment for reducing the risk of jaw osteonecrosis after tooth extraction in patients receiving medications associated with osteonecrosis?" MATERIAL AND METHODS:…
Conte Daniele, Roman Anna, Beorchia Yvonne, +3 more·Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
BACKGROUND: Parkinson's disease is a progressive neurodegenerative disorder that causes significant motor function limitations, substantially impacting the quality of life of affected individuals and their caregivers. While the currently available pharmacological therapy with levodopa can alleviate symptoms, identifyin…
Merhi M, Raynal H, Cahuzac E, +3 more·Cancer causes & control : CCC
OBJECTIVE: In this study we conducted a meta-analysis of 13 case-control studies that examined the occurrence of hematopoietic cancers in pesticide related occupations in order to undertake a qualitative and quantitative evaluation of a possible relationship. METHODS: Pubmed databases were searched for case-control st…
Hoffmann K K, Weber D J, Samsa G P, +1 more·JAMA
OBJECTIVE: To obtain a quantitative estimate of the impact on infectious complications of using transparent dressings with intravenous catheters. DATA SOURCES: Meta-analysis of all studies published in the English literature, including abstracts, letters, and reports that examined the primary research question of infe…
Braun Sarah R, Gregor Bettina, Tran Ulrich S·PloS one
OBJECTIVE: Despite numerous investigations, the question whether all bona fide treatments of depression are equally efficacious in adults has not been sufficiently answered. METHOD: We applied two different meta-analytical techniques (conventional meta-analysis and mixed treatment comparisons). Overall, 53 studies wit…
Cumming R G·Calcified tissue international
The relationship between calcium intake and bone mass remains controversial. In this paper, the published research on this association is reviewed using the quantitative technique of meta-analysis. Selection of studies was based on defined eligibility criteria, and information relating to study design was recorded. Stu…
Elgendy Mohamed S, Rifai Mohamed, Taha Amira M, +7 more·Gastrointestinal endoscopy
BACKGROUND AND AIMS: Accurate polyp measurement is vital for colorectal cancer treatment and surveillance. Traditional methods are often unreliable. The FDA-approved Virtual Scale Endoscopy (VSE) provides real-time, laser-calibrated overlays to improve size measurements. This meta-analysis evaluated the diagnostic accu…
Wen Sixiang, Yan Yushun, Shao Junru, +6 more·Translational psychiatry
OBJECTIVE: Gastrointestinal adverse effects are the most commonly reported adverse effects associated with the use of antidepressants. While existing studies on the gastrointestinal effects of antidepressant medications offer valuable insights, there are still opportunities to enhance the evidence base. METHODS: We in…