Topiramate monotherapy in epilepsy and migraine prevention.
Silberstein Stephen D, Ben-Menachem Elinor, Shank Richard P, +1 more·Clinical therapeutics
OBJECTIVES: The purposes of this review were to assess the efficacy of topiramate as monotherapy for epilepsy and migraine prevention, describe how it should be used, and give clinical advice on how to manage the practical aspects of dosing, titration, and possible adverse events in these 2 indications. METHODS: We se…