382,014 papers found

PURPOSE: This correspondence serves to critically evaluate the meta-analysis by Lin et al. regarding chatbot-led breast cancer education, focusing on specific methodological weaknesses that may undermine its core findings. METHODS: We performed a rigorous appraisal of the original study's methodology, specifically scr…

BACKGROUND: Antimicrobial resistance (AMR) is a significant public health crisis, particularly in Africa where infectious disease burdens are high. While antimicrobial stewardship programs (ASPs) are a key intervention, a comprehensive synthesis of their impact on antibiotic use in this context is lacking. OBJECTIVE:…

The Adverse Outcome Pathway (AOP) framework is a foundational approach in environmental pollutant research, encompassing the detrimental effects of pollutants across biological levels from molecules to populations. Toxicogenomics (TGx), which integrates omics technologies with toxicology, plays a crucial role in AOPs b…

There is growing interest in statistical modeling of data from single-case design (SCD) research. However, currently available methods such as hierarchical linear models and generalized linear mixed models have assumptions that may limit their utility for applied SCDs, such as those that use curriculum-based measures o…

INTRODUCTION: Cystoscopy has revolutionised the process of diagnosing bladder cancer leading to better categorisation of risk levels and more precise treatment plans. Nonetheless, concerns arise about the lack of uniformity among observers in predicting tumour stage and grade. To address these concerns, artificial inte…

When the coronavirus case was originally reported in Wuhan, China, in December 2019, it quickly spread throughout the world and became a global public health problem. Evidence of the admission and outcomes of coronavirus disease among patients with chronic obstructive pulmonary disease (COPD) has not been reported in A…

Type 2 diabetes (T2D) is a disease that impacts a huge portion of the world's population. The number of T2D cases is expected to keep rising during the next decade. Committing to the treatment to manage this condition makes participants feel a burden of emotions making them require emotional support from caregivers or…

BACKGROUND: Autoimmune diseases affect 5-10% of the global population and cause chronic pain and impaired functionality. Chronic pain management involves pharmacological and non-pharmacological interventions, with non-pharmacological options gaining attention as safe, effective, and cost-effective alternatives. However…

INTRODUCTION: There is still a lack of therapeutic options for long COVID. Several studies have shown the benefit of hyperbaric oxygen therapy (HBOT) on long COVID. However, the efficacy and safety of HBOT for long COVID remain unclear. Therefore, we will conduct this systematic review to assess the feasibility of HBOT…

INTRODUCTION: Post-stroke depression (PSD) is a prevalent complication that has been shown to have a negative impact on rehabilitation outcomes and quality of life and poses a significant risk for suicidal intention. However, models for discriminating and predicting PSD in stroke survivors for effective secondary preve…

Cannabis legalization is gaining traction in the United States, with 24 states having legalized recreational cannabis sales and 38 states having legalized medical cannabis sales. A possible unintended consequence of such widespread legalization is the effect that such policy change will have on youth (adolescents and y…

INTRODUCTION: Ethiopia is experiencing high prevalence of occupational morbidity and disability. One of the main contributing reasons is a low utilization of personal protective equipment (PPE). Previous studies on PPE utilization and association with educational status among industry workers were largely inconsistent.…

Health professionals and medical students are at increased risk of the imposter phenomenon (IP) in other words, the imposter syndrome, due to the challenging nature of their professions. It is particularly concerning since it is linked to a higher incidence of burnout and suicidal ideation. We must first thoroughly gra…

BACKGROUND: Delirium is a very common sick syndrome in patients receiving mechanical ventilatory support in the Intensive Care Unit (ICU). Music therapy is a promising non-pharmacological intervention. However, its effect on the duration, incidence and severity of delirium is unknown. So we will perform a systematic re…

BACKGROUND: Sleep deprivation often lead to changes in attention, memory, mood, alertness, and metabolism. Especially, it is often accompanied by cognitive impairment of the brain. Acupuncture is safe and effective for improving cognitive function, but its underlying mechanism is not fully understood. Resting-state fun…

BACKGROUND: The management of acute myocardial infarction (AMI) has improved dramatically over the past 3 decades and is evolving. Percutaneous coronary intervention is an alternative means of achieving coronary revascularization. Previous studies comparing the published literature on drug-coated balloon (DCB) and drug…