5,085,026 papers found

BACKGROUND: Norway is interested in implementing remote patient monitoring (RPM) within primary health services. This systematic review will first identify the types of RPM that are of interest to Norwegian health authorities, then synthesize the effects of RPM on clinical health and health service utilization outcomes…

We undertook a systematic review (incorporating meta-analysis) of the literature concerning the neurotoxicity of cumulative low level occupational exposure to organophosphate pesticides, which was published online by the journal Critical Reviews in Toxicology in 2012. As far as we are aware, we were the first research…

OBJECTIVE: This scoping review, conducted using a concept analysis framework, aims to synthesize the most robust evidence regarding suffering at the end of life (EOL), encompassing its attributes, antecedents, consequences, and empirical referents in nursing and other fields. INTRODUCTION: Suffering is a significant p…

BACKGROUND: Lifestyle diseases are commonly described as conditions arising from long-term behavioural patterns, occupational exposures, and broader civilisational and environmental determinants. Although the term is frequently used in public health and clinical literature, its conceptual boundaries remain heterogeneou…

Systematic reviews of health economic evaluations play a crucial role in informing evidence-based healthcare decisions, yet they lack standardized reporting guidelines. A project has been initiated that aims to extend the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline for systemat…

OBJECTIVE: The objective of this scoping review is to review the body of knowledge on net gain and no net loss (net-outcome) objectives and approaches applicable to health in spatial planning and development policies and practice. INTRODUCTION: There is an established body of academic and gray literature addressing en…

BACKGROUND: A learning health system (LHS) framework provides an opportunity for health system restructuring to provide value-based healthcare. However, there is little evidence showing how to effectively implement a LHS in practice. OBJECTIVE: A mixed-methods review is proposed to identify and synthesize the existing…

BACKGROUND: Asthma is one of the most common chronic respiratory conditions in the world and is increasing in prevalence, particularly in Africa and other low-income countries. The disproportionately high numbers of premature deaths and severe or uncontrolled cases in many African countries are indicative of their inab…

BACKGROUND: Depression and non-communicable diseases (NCDs) account for a growing burden on health systems in low- and middle-income countries (LMICs). Depression is generally associated with the outcomes of NCDs and is an important barrier to consistent NCD care management. There is great need to understand the effica…

INTRODUCTION: Liver transplantation is considered the best therapy option for end-stage liver disease. Different factors including recipient comorbidity at time of transplantation are supposed to have substantial impact on outcomes. Although several studies have focused on comorbidity assessment indices for liver trans…

BACKGROUND: Many medical residents lack ready access to social and emotional supports that enable them to successfully cope with the challenges associated with medical residency. This absence of support has been shown to lead to high levels of burnout, decreased mental wellbeing, and difficulty mastering professional c…

BACKGROUND: Systematic reviews of complex interventions can vary widely in purpose, data availability and heterogeneity, and stakeholder expectations. RATIONALE: This article addresses the uncertainty that systematic reviewers face in selecting methods for reviews of complex interventions. Specifically, it lays out pa…

INTRODUCTION: Dietary phytochemicals are found in plant-based foods such as fruits, vegetables and grains and may be categorised in a nested hierarchical manner with many hundred individual phytochemicals identified to date. To associate phytochemical intakes with positive health outcomes, a fundamental step is to accu…

BACKGROUND: Decision-makers increasingly request rapid answers to clinical or public health questions. To save time, personnel, and financial resources, rapid reviews streamline the methodological steps of the systematic review process. We aimed to explore the validity of a rapid review approach that combines a substan…

Librarians' contributions to systematic review projects receive inconsistent recognition within promotion or tenure processes. A review of thirty-six academic libraries' norms and procedures revealed only two that mentioned systematic reviews. Recognition and inclusion of systematic reviews and other evidence synthesis…

The main purpose of review articles is to increase insight into the best possible practice for increasing the health condition of future subjects. This requires the collection of as many relevant data as possible from earlier case studies, but such data should be mutually independent. If the data from the reviewed sing…

The overincarceration of Indigenous peoples and its impacts on individual and community health is a growing concern across Canada and the United States. Federally run Healing Lodges in Canada are an example of support services for incarcerated and previously incarcerated Indigenous peoples to reintegrate into community…

OBJECTIVE: To determine how often clinical conclusions derived from Cochrane Reviews have uncertain validity due to review conduct and reporting deficiencies. METHODS: We evaluated 5142 clinical conclusions in DynaMed (an evidence-based point-of-care clinical reference) based on 4743 Cochrane Reviews. Clinical conclus…

Single case reports remain a common form of scholarly submission, particularly from residents, students, and clinician-educators. Many are thoughtfully written and describe interesting clinical problems, yet most do not reach publication. The reason is rarely a lack of effort or clinical insight. More often, it is a pr…

This article identifies and unpacks three key decision points in a systematic mixed research synthesis, a mixed methods approach to research synthesis. The research community has increasingly recognized the value of synthesis studies in expanding our understanding of phenomena. Mixed-methodology broadly has also gained…