98,317 papers found

The continuing controversy between proponents of open and closed commissurotomy might be clarified by analysis of late follow-up with modern actuarial techniques that provide a true perspective of patient risk. We have used open mitral commissurotomy exclusively for 15 years in 100 patients. There was one operative dea…

Migraine is one of top 5 medical conditions that contribute to Years Lived with Disability and affects approximately 1 billion people from around the world. To date, preventive treatment and acute therapies for migraine are limited, have undesirable side effects and are poorly tolerated in patients. In the last few dec…

Nanomedicine is an emerging field, which constitutes a new direction in the treatment of cancer. Magnetic nanoparticles (MNPs) can circumvent vascular tissue to concentrate at the site of the tumor. Under the influence of an external, alternating magnetic field, MNPs generate high temperatures within the tumor and abla…

Several novel therapeutic agents have demonstrated ability to improve overall survival in metastatic castration-resistant prostate cancer (mCRPC) in recent years. With as many as 5 new agents approved within the last 5 years and an ongoing lack of comparative and prospective data, strategies for patient selection and s…

We examined the general health and psychological symptoms among survivors of the 1996 Garuda Indonesia air disaster in Japan. We conducted a prospective study 6 months and 1 year (Study 1) after the disaster. A retrospective follow-up study was performed ten years after the disaster (Study 2). The mean score on the 28-…

Adenocarcinomas account for 0.5-2% of all bladder cancers. Urachal carcinoma is a rare neoplasm which represents 0.01% of all cancers in adults and account for one third of bladder adenocarcinomas. A 65-year-old white man with an urachal mucinous adenocarcinoma is reported. None of the known predisposing risk factors f…

Piracetam, a derivative of gamma-aminobutyric acid (GABA), has been used extensively for treatment of myoclonus in a variety of conditions, but not in patients with idiopathic generalized epilepsy (IGE). We have treated a patient with juvenile myoclonic epilepsy who had frequent and inconvenient morning myoclonus with…

Multiplex wide incisions and often deforming scars following varicose surgery are out of date. Nowadays cryoprobes are used to remove epifascial varicose veins, while endoscopy is used to treat transfascial (perforating) venous insufficiency. We analyse the results of 1000 cryovaricectomies performed in the last 8 year…

We developed a simplified Politano-Leadbetter ureteral reimplantation associated with the psoas-hitch technique in 10 female patients, aged between 22 and 80 years, who were affected by pelvic ureteral pathology. After the standard ureteral mobilization through an intravesical and extravesical approach, the ureter was…

Special attention is given by the health legislation for protection of vulnerable groups and those who are exposed to high risk. The system of health care service is restructured and expanded in the way that accessibility, efficiency and effectiveness are improved. Public health insurance programme has priority and fun…

Limited evidence is available regarding the accuracy of recall for cancer screenings. We compared the self-report of stomach cancer screening with medical records in 337 residents of a rural town in northeastern Japan, who were eligible for annual screening offered by the town. Frequencies of attendance within the last…

During the last decade, the usefulness of functional endoscopic sinus surgery (FESS) has been clearly demonstrated in adult patients. Several recent studies have described the use of FESS in children. Most of the patients in these earlier studies have been school age or older. This paper will examine the follow-up of 4…

We reviewed 46 cases of Crohn's disease diagnosed during the period between 1978-1988, with the intention to analyse the age, sex, presentation, evolution, complications and diagnosis. The majority of patients were women, with a mean age of 39. In the last years we have seen an increment in our number of cases. The mea…

Postoperative intussusception is a rare but serious complication which occurs usually during the early postoperative period with intermittent, but progressing intestinal obstruction with characteristic appearance of mucus-bloody stools. Two children with postoperative intussusception have been observed among 381 childr…

This study reports the results of a survey on smoking of 214 children aged 7 to 9 years and 182 children aged 15 to 17 years. It was found that 27.1% of the younger group and 79.5% of the older group had tried to smoke a cigarette (even if just a few puffs). The frequency of continued smoking, as expected, was much gre…

Ivermectin paste formulation (200 micrograms/kg) was administered orally to 27 horses (13 Thoroughbreds and 14 of mixed breeding) to evaluate activity against adult Onchocerca spp in the ligamentum nuchae. Ages, known or estimated, of the horses ranged from 1 to 22 years. Single or multiple doses (1 to 5) of the drug w…

Although considered by many as the operation of choice in the treatment of duodenal ulcer, hyperselective vagotomy without drainage is not unanimously accepted because little is known about its long-term efficiency in preventing ulcer recurrence. The long-term results of 203 patients with duodenal ulcer, treated by hyp…

Fifty years after the publication of Harold Gillies' work, an assessment of zygomatic injuries is made, in the light of a half century of medical advances. Recent experience suggests that the fractured orbital floor is the commonest and most significant component of all zygomatic injuries. Exploration of 582 floors in…

Asthma incidence and prevalence have significantly increased during the last 25 years, making this pathology to be one of the most diffused in the industrialized world. It affects 5% of the adult population and the 10-15% of the children. The aethipathogenesis of asthma clearly involves a number of mediators, among whi…

Since the consumption of aromatic and medicinal herbs has been increasing in the last years, the Argentinian Health Authorities are concerned to control the quality and security of them. Fungal and aflatoxin contamination are two parameters to be taken into account, to ensure the harmlessness of the phytomedicinal prod…