Inherited lysosomal storage disease in an English springer spaniel.
Keller C B, Lamarre J·Journal of the American Veterinary Medical Association
Alpha-L-fucosidosis was diagnosed in a 17-month-old English Springer Spaniel with a history of slow development and progressive visual impairment. Lymphocytes and mononuclear cells with vacuolated cytoplasm were seen in a blood smear and in CSF, respectively. A severe deficiency of alpha-L-fucosidase activities in plas…