382,008 papers found

PURPOSE OF REVIEW: The difficult airway remains an ongoing concern in daily anesthesia practice, with awake intubation being an important component of its management. Classically, fiberoptic bronchoscope-assisted tracheal intubation was the method of choice in the awake patient. The development of new generation videol…

The rising number of medical publications makes it difficult to keep up-to-date on scientific knowledge. In recent years, reviews in the form of narrative or systematic publications and meta-analyses have increased. These can only be interpreted and evaluated if the reader understands the techniques used. This review a…

ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION: Optimal dose and duration of amoxicillin-plus-metronidazole as an adjunct to nonsurgical periodontal therapy: A systematic review and meta-analysis of randomized, placebo-controlled trials. McGowan K, McGowan T, Ivanovski S. J Clin Periodontol 2018;45:56-67. SOURCE OF FUNDI…

In recent years, due to the need to elaborate the amount of information available from the scientific literature, the meta-analyses and systematic reviews have become very numerous. The meta-analyses are carried out to evaluate the association between two events when single researches haven't provided comprehensive dat…

In repetitive transcranial magnetic stimulation (rTMS), repetitive cortical stimulation induces after-effects, and rTMS has been applied as a treatment for various neurological or psychiatric disorders. Animal studies demonstrated that cortical stimulation could improve Parkinsonism, and a meta-analysis of clinical stu…

Safety meta-analyses could play an important role in capturing fragmented safety data from underpowered clinical studies. Their utility, however, is hampered by the same constraints surrounding clinical studies, including limited external validity, inconsistent classification and the underreporting of safety data. When…

Using meta-analysis in health care research is a common practice. Here we are interested in methods used for analysis of time-to-event data. Particularly, we are interested in their performance when there is a low event rate. We consider three methods based on the Cox proportional hazards model, including a Bayesian ap…

Cronbach's coefficient alpha is the most widely used estimator of the reliability of tests and scales. However, it has been criticized as being a lower bound and hence underestimating true reliability. A popular alternative to coefficient alpha is composite reliability, which is usually calculated in conjunction with s…

Standard meta-analyses are an effective tool in evidence-based medicine, but one of their main drawbacks is that they can compare only two alternative treatments at a time. Moreover, if no trials exist which directly compare two interventions, it is not possible to estimate their relative efficacy. Multiple treatments…

In anterior resection of rectum, the section level of inferior mesenteric artery is still subject of controversy between the advocates of high and low tie. The low tie is the division and ligation to the branching of the left colic artery and the high tie is the division and ligation at its origin at the aorta. We inte…

The M3 workshop has, as its primary focus, the rapidly growing area of metagenomics, including the metadata standards and the meta-analysis approaches needed to organize, process and interpret metagenomics data. The PSB Workshop builds on the first M3 meeting, a Special Interest Group (SIG) meeting at ISMB 2009, organi…

Individuals with diabetes have an increased risk of cardiovascular disease. Epidemiological studies demonstrate that plasma glucose (PG) concentrations in the upper normal range are an independent risk factor for cardiovascular disease, as discussed in a meta-analysis. Studies carried out mainly in the general populati…

(1) A prospective study in Germany showed that 12% of hospitalised children experienced adverse drug reactions. These reactions were the reason for hospitalisation in 1.8% of cases. (2) A meta-analysis of 17 prospective studies of adverse drug reactions in children, published in 2001, and two French prospective studies…

Epidemiological studies suggest an inverse relationship between physical activity or fitness and blood pressure. In a meta-analysis of 44 randomized controlled intervention trials, the weighted net change in conventional systolic/diastolic blood pressure in response to dynamic aerobic training averaged -3.4/-2.4 mmHg (…