44,672 papers found

Takotsubo cardiomyopathy (TTC), or stress-induced cardiomyopathy, is characterized by transient left ventricular dysfunction often triggered by emotional or physical stress. Although classically associated with postmenopausal women under psychological stress, cases among endurance athletes, particularly marathon runner…

BACKGROUND: Intrahospital transportation of critically ill patients is a high-risk process, frequently linked to complications and increased vulnerability to adverse events. Ensuring safety requires nursing interventions that uphold the standards of care provided in critical care units. OBJECTIVE: To identify nursing…

BACKGROUND: The cause of neck pain after whiplash is regarded as unknown, but Bioengineers have published studies implicating subfailure injuries of the cervical zygapophysial joints as a leading cause of pain. OBJECTIVES: A scoping review was undertaken to determine the size and nature of the evidence for subfailure…

BACKGROUND: Kinesio Taping (KT) is commonly used in musculoskeletal disorders and rehabilitation practice, but its role in spinal cord injury (SCI) has received little scientific attention. OBJECTIVE: This scoping review aimed to map the existing literature on KT use in persons with SCI, describing how it has been app…

AIMS: This study aimed to provide a clear definition of the concept of maternal stress in the neonatal intensive care unit (NICU), which has been inconsistently described in previous studies. It also aimed to identify the essential attributes, antecedents, and consequences of maternal stress through concept analysis.…

Although rare, neurotrauma has been documented as a potential risk of high-speed, high-acceleration amusement park rides such as roller coasters. These attractions generate rapid acceleration, deceleration, sharp turns, and significant gravitational forces, which may stress the central nervous system and cerebrovascula…

Differential diagnosis is crucial for medicine as it helps healthcare providers systematically distinguish between conditions that share similar symptoms. This study assesses the impact of lab test results on differential diagnoses (DDx) made by large language models (LLMs). Clinical vignettes from 50 case reports from…

Tenecteplase (TNK), a genetically modified tissue plasminogen activator, has emerged as a promising alternative to alteplase (ALT) for intravenous thrombolysis (IVT) in acute ischemic stroke (AIS). Our aim was to synthesize the current clinical evidence on TNK use in AIS patients, comparing efficacy, safety, and workfl…

BACKGROUND: Nasal drug delivery offers a non-invasive route with rapid absorption and the ability to bypass first-pass metabolism, making it promising for central nervous system (CNS) disorders, nasal diseases such as allergic rhinitis, and other chronic conditions by enabling targeted delivery and crossing the blood-b…

Viral conjunctivitis is a highly contagious ocular condition that significantly impacts patient quality of life and healthcare resources. Despite its self-limiting nature, the condition remains a significant public health concern due to its high transmissibility, prolonged symptoms, and potential complications such as…

OBJECTIVE: To synthesize the current evidence on the relationship between different management leadership styles and nurses' turnover intentions in hospital settings. BACKGROUND: A shortage of nurses is a common problem in healthcare institutions in many countries. In this context, retaining nurses has become a critic…

In this review, we holistically consider healthcare as an ecosystem that includes forensic pathology and legal medicine and probe why these areas have largely ignored the use of Metaverse. This effort is directed at understanding the potential impact of virtual worlds on these areas and ultimately asks if forensic scie…

BACKGROUND: We aimed to examine how electroacupuncture and manual acupuncture affect treatment results, pain levels, and joint function in individuals with knee osteoarthritis. METHODS: Research was carried out in various databases including PubMed, Medline, Embase, CENTRAL, and CNKI. Following the "Cochrane manual",…

This article explores the potential therapeutic implications of phytochemicals on the gut-brain axis (GBA), which serves as a communication network between the central nervous system and the enteric nervous system. Phytochemicals, which are compounds derived from plants, have been shown to interact with the gut microbi…

BACKGROUND: Primary Sjögren's syndrome (pSS) is recognized for its autoimmune origin. Its hallmark symptoms, dry eyes and mouth, result from glandular inflammation. Prior literature indicates that pSS not only affects the peripheral system but also involves the central nervous system (CNS), giving rise to various…

BACKGROUND: Academic advancement of the midwifery profession highlights the need to establish standardized qualifications in obstetric ultrasound diagnosis, being a central part of prenatal care. Thus, introduction of an evidence-based training program is warranted. We aimed to reviewed curriculum designs used in midwi…

Mucocutaneous leishmaniasis is a severe infectious disease, predominantly endemic in Central and South America and is characterized by granulomatous, destructive mucosal lesions in the oral, nasal, and pharyngeal cavities. It is caused by protozoa of the genus Leishmania spp. transmitted to humans by sandflies. Mucocut…

Obesity is increasing in prevalence worldwide and carries a theoretical increased risk of morbidity and mortality in critical illness, including hypercoagulability, thrombosis, and renal dysfunction. Obesity has historically been considered a relative contraindication to candidacy for extracorporeal membrane oxygenatio…

This systematic literature review aims to determine the optimal initial dose of naloxone for successful opioid overdose reversal across different administration routes. Types of participants included adults who have opioid overdoses and adults who are suspected to have opioid overdoses. Pregnant women, children, a…

BACKGROUND: Perianal manifestations of Crohn's disease (CD) are common, with fistulas being the most prevalent and challenging to manage. OBJECTIVE: The aim of this articles was to describe and explain how Perianal fistulizing Crohn's disease significantly impacts patients' quality of life and poses a therapeutic chal…