5,006,524 papers found

INTRODUCTION: The objective of this study is to determine the extent and describe the nature of patient-generated health data (PGHD) integration into electronic health records (EHRs) using systematic scoping methods to review the available literature. PGHD have the potential to enhance decision making by providing the…

OBJECTIVE: This scoping review aims to map the use of post-discharge interventions to enhance coping skills for adult stroke survivors and their informal caregivers. INTRODUCTION: Evidence shows that when stroke survivors and their informal caregivers are provided with post-discharge coping training, their outcomes im…

OBJECTIVE: The objective of this review is to examine the association between serum testosterone concentration and the presence and severity of depression in men. INTRODUCTION: Cross-sectional and longitudinal cohort studies examining the relationship between serum testosterone concentration and depression in men have…

INTRODUCTION: Primary motor cortical (M1) adaptation in the form of altered organisation and function is hypothesised to underpin motor dysfunction observed in chronic pain. The aim of this review is to assess the evidence for altered M1 organisation and function in chronic pain. METHODS AND ANALYSIS: Systematic revie…

The current difficulties in keeping systematic reviews up to date leads to considerable inaccuracy, hampering the translation of knowledge into action. Incremental advances in conventional review updating are unlikely to lead to substantial improvements in review currency. A new approach is needed. We propose living sy…

BACKGROUND: Desk reviews are widely used in health policy research, yet standardized procedures are lacking. This becomes particularly problematic when working with regulatory and professional documents that are not indexed in academic databases, making access and analysis fragmented. PURPOSE: The paper aims to propos…

Systematic review and meta-analysis constitute a staple of evidence-based medicine, an obligatory step in developing the guideline and recommendation document. It is a formalized process aiming at extracting and summarizing knowledge from the published work, grading, and considering the quality of the included studies.…

BACKGROUND: Chronic disease of childhood may be delayed by early dietary intervention. The purpose of this systematic review is to provide decision-makers with a perspective on the role of early dietary intervention, as a form of self-management, to delay disease progression in children with early chronic disease, as d…

INTRODUCTION: Compared to women with normotensive pregnancies, women with a history of pre-eclampsia have a roughly fourfold increased risk of developing chronic arterial hypertension and a twofold increased risk of developing cardiovascular disease (CVD). Lifestyle changes, such as increased physical activity, weight…

INTRODUCTION: Twenty years ago, the first study was conducted to access adverse childhood experiences (ACEs) and their relation to outcomes in adulthood. The effects of exposure to childhood trauma can also be transmitted to other generations. There are some studies that suggest the hypothesis that intergenerational tr…

INTRODUCTION: Suicide is one of the leading causes of death worldwide, especially in patients with mental health disorders. Suicidality is an important outcome for patients in psychiatric randomised clinical trials. The aim of this scoping review is to assess whether and how psychiatric trials assess suicidal ideation,…

INTRODUCTION: Conducting a rigorous systematic review of animal studies requires a priori registration of a study protocol. However, it remains unknown how many of these registered studies culminate in publication and how long it takes to complete such a systematic review. Thus, this study had two objectives: (1) to as…

INTRODUCTION: The number of babies, children and young people with complex care needs (henceforth children with complex care needs (CCCN)) in England has increased in recent decades, and this has also been recognised globally. CCCN may have frequent and lengthy hospital admissions, but during these episodes, their need…

OBJECTIVES: It was recognised in the 1978 Alma-Ata Declaration that the integration of traditional medicine into modern health systems is a major lever for achieving universal health coverage. In several African countries, the integration of traditional medicine still faces constraints, despite the development of polic…

INTRODUCTION: Fever is an integral part of the inflammatory response and has therefore likely a physiological role in fighting infections. Nevertheless, whether fever in itself is beneficial or harmful in adults is unknown. This protocol for a systematic review aims at identifying the beneficial and harmful effects of…

AIM: This protocol proposes a systematic review to identify and disclose learning strategies and evaluation tools to improve Emotion Intelligence (EI) in undergraduate nursing students. BACKGROUND: EI improves the ability to manage emotions and their consequences. Management of emotions is fundamental in nursing both…

This article summarizes our deepened understanding of decolonizing research with, for, and by Indigenous peoples and peoples of African descent that emerged from conducting a scoping review of the methodological literature and reflecting on our review process. Although our review identified decolonizing methodologies a…

OBJECTIVES: The objective of this study was to survey how outcomes in recent Cochrane reviews were defined and used for inclusion of studies and how this compares with guidance on preventing outcome reporting bias. STUDY DESIGN AND SETTING: A survey of Cochrane reviews. We extracted data on the outcomes and how the ou…

This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To evaluate the benefits and harms of androgens compared to placebo or no intervention, or another active treatment for genitourinary and vasomotor symptoms in perimenopausal or postmenopausal women.

This paper introduces the Risk of Bias in Systematic Review (ROBIS), including: 1) the development of ROBIS, 2) three phases of ROBIS tool judging the overall risk of bias that related to systematic reviews, and 3) illustration on the application of ROBIS in a published systematic review. ROBIS is the first rigorously…