11,610,369 papers found

BACKGROUND: High blood pressure (BP) is becoming increasingly common among young adults, with university students representing a particularly vulnerable group, posing a growing public health challenge worldwide. The study explores the relationship between BMI and demographic characteristics related to elevated BP in th…

The aerial parts of the species Ageratina pichinchensis, popularly known as "axihuitl", have been empirically used in Mexico for wound-healing purposes. The evaluation of an extract from A. pichinchensis (in an in vivo model) demonstrated its capacity to reduce, in a significant manner, the time required for wound heal…

BACKGROUND: The prevalence of kidney stones is on the rise globally. Several risk factors, including lifestyle, contribute to the formation of kidney stones. Nevertheless, there is a contentious debate about the relationship between diet and kidney stones. Therefore, our study aimed to assess the relationship between m…

PURPOSE: To evaluate the effectiveness of oral corticosteroid therapy in patients with stable chronic obstructive pulmonary disease. DATA IDENTIFICATION: An English-language literature search using MEDLINE (1966 to 1989) and a bibliographic review of all retrieved articles identified 33 original studies of oral cortic…

INTRODUCTION: Effective management of hypertension often requires pharmacological intervention, which can involve either single pill combination therapy (SPC) or multiple pill combination therapy (MPC). However, the choice between SPC and MPC can be influenced by patient demographics, clinical characteristics, comorbid…

Substance abuse among university students is a significant public health concern that is typically linked to underlying mental health issues such as depression, stress, and a lack of social support networks. Thus, the study's goal was to investigate the link between social support, depression, and substance abuse. A cr…

Real-world evidence (RWE) is increasingly used to inform healthcare delivery and expedite access to new therapies, but its value depends on the quality and completeness of information in real-world data (RWD) sources. Tokenization technology enables the integration of patient data from multiple sources, facilitating th…

PURPOSE: This study explores how walking difficulty and activity relate to depression in older adults using data from the MOBILIZE Boston Study. METHODS: We analyzed data from 765 community-dwelling older adults from the study's baseline assessment. Depression was measured using the 20-item Hopkins Revision of the Cen…

BACKGROUND: The substantial caregiving burden associated with managing disabled patients following traumatic brain injury (TBI) imposes significant psychological and physical strain on spouses. Given that spousal well-being directly impacts patient recovery outcomes, family stability, and broader societal resilience, t…

BACKGROUND: Previous studies have evaluated traditional Chinese medicine (TCM) clinical randomized controlled trial (RCT) literature broadly, but they have provided limited depth in evaluating the specific aspects of trial quality. OBJECTIVE: This study aims to develop a specialized literature quality assessment syste…

OBJECTIVE: To study the biopsychosocial model of chronic low back pain in the workplace and the role of sex in it. DESIGN: Cross-sectional nationwide survey in a service company. PATIENTS: 256 workers (women 64.1%) reporting chronic low back pain. METHODS: Variables on biometry, job description, physical activity, p…

AIMS: To investigate the effects of a specific balance training (BT) on lower extremity functions during and after pediatric oncological therapy. METHODS: During a 6-week intervention (DRKS00031418), children with cancer during (IG1) and after (IG2) acute oncological treatment participated in a child-friendly BT up to…

Previous data have demonstrated the feasibility of robot-assisted radical prostatectomy (RARP) performed with the Dexter robotic system. This study aimed to assess the early functional and oncological outcomes of RARP performed at our center using Dexter.Forty-seven consecutive patients underwent RARP ± lymph node…

The dual-factor model (DFM) of mental health has received increasing support in recent years. However, researchers have limited knowledge regarding the longitudinal changes in the DFM of mental health. This study considered the dual-factor mental health among adolescents using latent profile analysis (LPA). It explored…

OBJECTIVE: To evaluate the factors associated with Medicare spending on newly approved anticancer drugs in the US from 2012 through 2021. PATIENT AND METHODS: Using a cross-sectional analysis, we searched US FDA new oncology drug approvals (2012-2021). We analyzed clinical attributes and institutional factors influenc…

BACKGROUND: It is critical to examine the pathogenic pathways in coronavirus disease 2019 (COVID-19) that resulted in the development of severe lung injury. Surfactant protein B (SFTPB) is a vital component for sustaining life and serves pivotal functions in the host's defensive mechanisms and alveolar surface tension…

BACKGROUND: Bullying in school is a universal psychosocial issue that raises concerns about adolescents' safety and mental health and is positively associated with depressive symptoms. Social support could be a preventive factor that eases bullying and its psychological distress. PURPOSE: The primary purpose of this s…

Although the quality of care during childbirth is a maternity service's goal, less is known about the impact of the birth setting dimension on provision of care, defined as evidence-based intrapartum midwifery practices. This study's aim was to investigate the impact of hospital birth volume (&#x2265;1000 vs. <1000 bir…

Guillain-Barre Syndrome (GBS) is considered as an immune mediated inflammatory disease of peripheral nerves and nerve roots. The significance of CSF total protein (CSF-TP) in subtypes of Guillain-Barre syndrome has not been well established. This observational, cross sectional study's aim was to identify association of…

PURPOSE: The main aim of this study was to investigate the clinical efficacy of speech therapy, delivered via tele-practice to patients with dysphonia. A secondary aim was to verify whether a telerehabilitation-only protocol could have a clinical efficacy similar to a combined telerehabilitation and in-person approach.…