42,368 papers found

BACKGROUND: We reviewed the literature to assess the prognostic ability of the geriatric nutritional risk index (GNRI) for patients with colorectal cancer (CRC) undergoing curative surgery. METHODS: The online databases of PubMed, CENTRAL, ScienceDirect, Embase, and Google Scholar were searched for articles reporting…

Active exergaming for improving cognitive function is a relatively novel concept as it has certain unique features that could prove advantageous in improving patient outcomes, particularly in patients with neurological disabilities. Hence, we have conducted this review to obtain a comprehensive estimate of effectivenes…

BACKGROUND: The tic disorders are common neuropsychiatric disorders that affects the growth and development of children and adolescents. Chinese herbal medicine is commonly used for the treatment of tic disorders. However, there is no consensus on the difference in clinical efficacy compared with routine treatment. The…

BACKGROUND: Interstitial lung disease (ILD) is a category of chronic lung diseases with more than 200 subtypes. Idiopathic interstitial pneumonia (IIP), systemic sclerosis (SSc) ILD, and familial interstitial pneumonia (FIP) are three major groups of lung diseases with different causes or with unknown causes. Mucin5B (…

BACKGROUND: Extraction is the foremost step to isolate the natural constituents from a medicinal plant and leads the process of development of herbal formulation from bench to bed. INTRODUCTION: In the field of extraction, the optimization approach helps in achieving better yield and quality where a response of concer…

COVID-19 is caused by SARS-CoV-2, which originated in Wuhan, Hubei province, Central China, in December 2019 and since then has spread rapidly, resulting in a severe pandemic. The infected patient presents with varying non-specific symptoms requiring an accurate and rapid diagnostic tool to detect SARS-CoV-2. This is f…

Glutamine is a conditionally essential amino acid widely used in sports nutrition, especially because of its immunomodulatory role. Notwithstanding, glutamine plays several other biological functions, such as cell proliferation, energy production, glycogenesis, ammonia buffering, maintenance of the acid-base balance, a…

is a valuable medicinal plant species among different ethnic groups in tropical Africa. The aim of the current study was to review existing literature on the ethnomedicinal uses, phytochemistry and pharmacological properties ofin an effort to evaluate the therapeutic potential of the species. The relevant information o…

Traumatic brain injury (TBI) is now characterized as a progressive, degenerative disease and continues to stand as a prevalent cause of death and disability. The pathophysiology of TBI is complex, with a variety of secondary cell death pathways occurring which may persist chronically following the initial cerebral insu…

BACKGROUND: Diving is a popular sport, and some recreational divers have medical risk factors. Their health can be endangered by high extracorporeal (ambient) pressure and its many systemic effects. METHODS: We review relevant publications on free (breath-hold) diving, scuba diving, medical evaluation for diving, baro…

PURPOSE: We conducted a meta-analysis of all published case-control and cohort studies to evaluate the relationship between vegetables intake and liver cancer risk. METHODS: We searched for cohort and case-control studies published before February 2014, using Pubmed and Cochrane Library Central database. Pooled relati…

BACKGROUND: Lateral elbow tendinopathy (LET) is the most common musculoskeletal elbow disorder. Evidence suggests that cervicothoracic involvement often contributes to forearm symptoms and that addressing the spine improves clinical outcomes. This review aimed to evaluate screening methods for the cervicothoracic spine…

Over 120 phytocannabinoids and 190 synthetic and semi-synthetic cannabinoids have been identified. Many of these currently circulate in recreational and illicit drug markets. Epidemiological evidence indicates a progressive increase in their use but long-term effects of cannabinoids on the CNS remain poorly understood.…

BACKGROUND: Given the central role of writing and typing in contemporary communication, integrating writing assessments into clinical practice is crucial for improving the diagnosis and management of primary progressive aphasia (PPA). This scoping review summarizes evidence on writing abilities in PPA, examining task t…

OBJECTIVES: We reviewed weight loss and gaining wrinkles, and the impact of weight loss drugs on facial aesthetics. METHODS: The resources from Eskişehir Osmangazi and Kirikkale Universities, along with Google, Google Scholar, PubMed, EBSCO, and ProQuest Central, were consulted for the literature review. Between…

BACKGROUND: This bibliometric study scrutinizes the thematic evolution of research on stigma and discrimination in mental disorders, covering a span of five decades. It reflects on the shifting paradigms within the stigma-focused mental health research community from 1974 to 2024. METHODS: A comprehensive bibliometric…

Multidisciplinary meetings (MDMs) are increasingly central to spinal oncology, where complex decision-making must balance neurological, oncological, biomechanical, and systemic factors. This review aims to analyze the structure, clinical value, limitations, and future directions of MDMs in the management of spinal tumo…

Loiasis, a filarial vector-borne disease, is common in rural West and Central Africa. Benzimidazole derivatives albendazole and mebendazole are recommended as alternative treatments due to their perceived safety in hypermicrofilaremic patients. There is growing evidence that benzimidazoles might also lead to-associated…

BACKGROUND: Persons with dementia have increased risk of malnutrition due to several challenges. There is a wide range of interventions to improve nutritional status in persons with dementia. However, the evidence for such interventions is uncertain. AIM: To investigate the effect of therapeutic interventions to impro…

INTRODUCTION: Randomized controlled trials have suggested that tretinoin, a topical retinoid, can improve wrinkling in photodamaged skin; however, its overall effectiveness remains subject of debate. OBJECTIVES: This study evaluated the efficacy and safety of tretinoin in treating facial wrinkles induced by photodamag…