5,084,297 papers found

BACKGROUND: Impairments in social cognition are known to be a key factor in several psychiatric and neurodevelopmental disorders. Interest in psychedelic drugs has increased in recent years, with significant research identifying psychedelic and hallucinogenic drugs as modulators of social cognition. However, more resea…

BACKGROUND: Inter-hospital transfer is necessary for the transport of patients to specialized treatment. Rotor-wing aircraft may be used in lieu of ambulances in time-critical conditions over long distances and when specialist team skills are called for. The purpose of the review is to assess the current scientific lit…

BACKGROUND: Remimazolam, a novel intravenous benzodiazepine recently approved by both the European Medicines Agency and the Food and Drug Agency, holds significant promise in clinical practice. Its pharmacodynamic profile closely mirrors that of midazolam, while its pharmacokinetics properties bear resemblance to remif…

OBJECTIVE: The objective of this scoping review is to describe models of palliative care for under-served populations in high-income countries, defined as adults of culturally and linguistically diverse communities, low socioeconomic status, and/or residing in rural areas. INTRODUCTION: Models of palliative care are p…

BACKGROUND: Despite growing interest in incorporating holistic review within residency admissions, implementation by residency programs remains challenging. OBJECTIVE: To incorporate holistic review into the internal medicine residency program at the University of Wisconsin and to report initial feasibility and accept…

OBJECTIVE: The objective of this review is to identify the outcomes of family presence at the bedside of critically ill children in pediatric intensive care units (PICUs) that have been reported in the literature. INTRODUCTION: PICU admission is traumatic for critically ill children and their family members, and famil…

INTRODUCTION: Even if a positive volume-outcome correlation in surgery is mostly admitted in many surgical fields, the various ways to assess this relationship make it difficult for researchers and policymakers to use it. Our aim is therefore to provide an overview of the way hospital volume-outcome relationship was as…

BACKGROUND: Acupoint herbal patching (AHP) is widely used for symptom management in patients with acute and chronic bronchitis. The purpose of this protocol review is to evaluate the safety and efficacy of AHP for the treatment of bronchitis. METHODS AND ANALYSIS: This protocol of systematic review will be conducted i…

INTRODUCTION: This systematic scoping review will explore the role of regulation on the care of older people living with depression in long-term care. Depression presents a significant burden to older people living in long-term care. Regulation in the long-term care sector has increased, but there are still concerns ab…

The objective of the scoping review is to locate and describe the international literature relating to Nursing Sensitive Indicators (NSIs) and their use in evaluating geriatric care. Specifically the review question is: What definitions and key concepts of NSIs are identified in the current literature that are relevant…

The overarching objective of this review is to enhance understanding of the lived experiences of parents and carers in managing a child with asthma. Enablers and barriers encountered by parents will be examined and findings of the review will be used to develop recommendations for enhancing policy and practice aimed at…

Systematic reviews and meta-analyses that obtain original research data on individual participants enrolled in trials have been described as the gold standard of review. However, they may take longer and be more resource intensive than other types of review. The authors describe potential advantages and disadvantages o…

Systematic reviews are increasingly used to combine the results of several studies in order to define the treatment effect with a high degree of precision. However, reviews of this nature may lead to spurious results and should not be accepted uncritically. This article, the second in a series on evidence-based psychop…

In contrast to traditional narrative reviews, systematic reviews are true hypothesis-driven research. Meta-analysis is a form of systematic review in which studies are selected and combined by use of a predefined protocol to reduce bias and subjectivity. A sensitivity analysis shows how results vary through the use of…

BACKGROUND: Digital mental health interventions (DMHIs) offer scalable solutions to address mental health needs, particularly among marginalized populations. However, engagement and adherence rates in DMHIs are often suboptimal, limiting their potential impact. Despite the growing body of literature on DMHI engagement,…

BACKGROUND: Multimorbidity, defined as the coexistence of multiple chronic conditions, poses significant challenges to health care systems on a global scale. It is associated with increased mortality, reduced quality of life, and increased health care costs. The burden of multimorbidity is expected to worsen if no effe…

Health care is constantly being reformed to improve the safety and quality of services, and nurses are integral to the provision of this safety and quality. As a result of concerns raised by recent high-profile care failings, there is an expectation that the nursing profession should be able to meet the changing demand…

BACKGROUND: Respiratory failure requiring mechanical ventilation is a common manifestation of end-organ damage among patients with sepsis and has a high morbidity and mortality rate, as well as substantial associated treatment costs. Considering the burden of this condition, there is great need to identify novel, pragm…

OBJECTIVE: To identify methods to support the node-making process in network meta-analyses (NMAs) of nonpharmacological treatments. STUDY DESIGN AND SETTING: We proceeded in two stages. First, we conducted a literature review of guidelines and methodological articles about NMAs to identify methods proposed to lump int…

INTRODUCTION: The global burden of cancer is escalating, with Asia accounting for over half of cancer-related deaths worldwide. As cancer often diminishes patients' quality of life and sense of dignity, dignity-related interventions have gained prominence in palliative care for patients with cancer. However, a more in-…