5,084,101 papers found

This commentary looks at the process of conducting a systematic review of surveys and validated questionnaires. Surveys and other questionnaire style tools are often used in the field of social and administrative pharmacy, to capture beliefs, attitudes and experiences of patients and healthcare professionals (including…

Long-term survival rates for childhood, adolescent, and young adult cancers have increased substantially, yet survivors often face ongoing physical, psychological, and social challenges. Family dynamics play a key role in survivor adjustment. Family accommodation, defined as behaviour modifications by family members in…

INTRODUCTION: Anterior uveitis is an intraocular inflammatory condition that can lead to vision impairment without appropriate and timely treatment. Determining its aetiology can be difficult due to its heterogeneous clinical presentations, which challenges effective treatment. The primary aim of this systematic review…

INTRODUCTION: Hypoxic-ischaemic encephalopathy (HIE) is a leading cause of neonatal mortality and long-term neurodevelopmental impairment worldwide. Neonatal seizures are common in HIE and are associated with adverse outcomes. While antiseizure medications are routinely used for treatment, their prophylactic use in the…

INTRODUCTION: Opioid use disorder (OUD) remains a serious and life-threatening disease. Medications for opioid use disorder (MOUD) are effective treatments for OUD but a minority of eligible patients receive them. Hospitalisation is an opportune time to increase MOUD use. However, the description of the most successful…

OBJECTIVE: This review seeks to understand the global trends of contemporary witchcraft accusations and related harms against children and adolescents (0-18 years of age). INTRODUCTION: Witchcraft-related violence against children and adolescents (children) reflects an alarming and understudied phenomenon of socio-cul…

OBJECTIVE: This scoping review aims to map the social dimensions of kidney care pathways. INTRODUCTION: End-stage kidney disease places significant demands on patients, caregivers, healthcare professionals, and the broader healthcare system. Kidney replacement therapy and conservative kidney management are the common…

INTRODUCTION: In recent decades, differences in the risk factors, presentations, management strategies and outcomes of acute myocardial infarction (AMI) between the sexes have emerged. Several systematic reviews and meta-analyses (SMRAs) on this specific topic have been conducted, and an overall assessment of the infor…

BACKGROUND: Aeromedical transfer of patients with ischemic stroke to access hyperacute stroke treatment is becoming increasingly common. Little is known about how rapid changes of altitude and atmospheric pressure can impact cerebral perfusion and ischemic burden. In patients with ischemic stroke, there is a theoretica…

INTRODUCTION: Digital technologies present tremendous opportunities for enabling long-term measurement of mental health in the general population. Emerging studies have established preliminary efficacy of collecting self-report data digitally. However, a key challenge when developing a new self-report instrument is nav…

OBJECTIVE: The aim of this review is to determine whether suture button fixation is more effective than traditional screw fixation for the management of acute distal tibiofibular syndesmotic injuries. INTRODUCTION: Syndesmotic injuries are common and require surgical management to avoid chronic pain and instability, a…

BACKGROUND: Approximately half of people with heart failure have chronic kidney disease (CKD). Tolvaptan is reported to be effective in treating heart failure. However, the safety and efficacy of its use in patients with CKD is uncertain. In this study, we conducted a protocol for systematic review and meta-analysis to…

INTRODUCTION: Misuse of psychoactive medicines, especially prescription opioids, but also benzodiazepines, hypnotics and sedatives, has become a significant public health issue in some countries, especially in the USA, where it has been extensively documented, as well as in Canada and Australia. However, in the Europea…

In many low- and middle-income countries (LMICs), the epidemiological transition is characterized by an increased burden of non-communicable diseases (NCDs) and the persistent challenge of infectious diseases. The transmission of tuberculosis, one of the leading infectious diseases, can be halted through active screeni…

INTRODUCTION: Urinary tract infection (UTI) is a frequently diagnosed infection in women and children. Treatments are often initiated with broad-spectrum antibiotics without performing any culture and sensitivity test. Inappropriate and empirical antimicrobial regimens and poor adherence to the drugs lead to the recurr…