Individual participant data meta-analysis of intervention studies with time-to-event outcomes: A review of the methodology and an applied example.
de Jong Valentijn M T, Moons Karel G M, Riley Richard D, +4 more·Research synthesis methods
Many randomized trials evaluate an intervention effect on time-to-event outcomes. Individual participant data (IPD) from such trials can be obtained and combined in a so-called IPD meta-analysis (IPD-MA), to summarize the overall intervention effect. We performed a narrative literature review to provide an overview of…