42,210 papers found

BACKGROUND: The efficacy of induction treatment plus surgery for improving postoperative survival in patients with non-small-cell lung cancer (NSCLC) in stages IIIA-N2 is controversial, especially compared with the combined chemotherapy and radiotherapy. We therefore performed a systematic review and meta-analysis of t…

OBJECTIVE: To review available medical therapies for patients with Cushing disease and to provide a roadmap for their use in clinical practice. METHODS: PubMed searches were performed to identify all of the available published data on medical management of Cushing disease. RESULTS: Medical therapy is usually not the…

BACKGROUND AND OBJECTIVE: For locally advanced cervical cancer, the typical radiation treatment is a combination of external beam radiation therapy (EBRT) and brachytherapy. However, variation exists in brachytherapy technique selection and implementation, stemming from differences in imaging access, operator experienc…

Medetomidine is a relatively new sedative analgesic drug that is approved for use in dogs in Canada. It is the most potent alpha2-adrenoreceptor available for clinical use in veterinary medicine and stimulates receptors centrally to produce dose-dependent sedation and analgesia. Significant dose sparing properties occu…

BACKGROUND: Medicinal plants present activities against neurodegenerative diseases with potential for the pharmaceutical industries. Therefore, the objective of this study was to investigate the current panorama of patents and articles of Brazilian medicinal plants with pharmacological activities in the Central Nervous…

INTRODUCTION: Nonsurgical and surgical management of periimplant mucositis and periimplantitis have shown promising results in arresting periimplant marginal bone loss (MBL) and preventing implant loss. However, management of periimplant diseases still remains unpredictable for full reconstruction of lost tissues and c…

Plastic surgery on the breast is among the most common aesthetic and reconstructive procedures performed today, with a variety of surgical approaches available. Emerging evidence suggests that these procedures may negatively affect breastfeeding. This meta-analysis aimed to assess the effects of breast augmentation, re…

Controversies exist in literature regarding nature, pathogenesis, and behaviour of giant cell lesions (GCLs) of jaws. Studies were attempted to solve these mysteries with immunohistochemical analysis, using various biological markers. Thus, the aim of this review is to appraise the role of immunohistochemistry (IHC) in…

Biomedical publishing stands at a crossroads. The traditional print, peer-reviewed, subscription journal has served science well but is now being called into question. Because of spiraling print journal costs and the worldwide acceptance of the Internet as a valid publication medium, there is a compelling opportunity t…

BACKGROUND: To combat the coronavirus pandemic different vaccines have been developed. However, diverse adverse effects have been reported due to their use, including oral manifestations. Our objective is to review the existing bibliography to analyze what complications these vaccines have caused in the oral cavity. M…

OBJECTIVE: Analyze the state of the art about instruments, at national and international levels, for assessing the risk of suicide in elderly people with depression assisted in the community. METHODS: Integrative review of 38 complete articles, published in journals indexed in the databases: US National Library of Med…

The availability of research data sets is an important milestone because it can enhance the dynamics of research. This study aims to analyze the PubMed Central repository to determine the availability and type of raw data sets in Cell & Tissue Engineering journals indexed in Journal Citation Reports. The number and typ…

The Nuclear Protein Database (NPD) is a curated database that contains information on more than 1300 vertebrate proteins that are thought, or are known, to localise to the cell nucleus. Each entry is annotated with information on predicted protein size and isoelectric point, as well as any repeats, motifs or domains wi…

OBJECTIVE: to identify and synthesize the evidence from randomized clinical trials that tested the effectiveness of traditional Chinese acupuncture in relation to sham acupuncture for the treatment of hot flashes in menopausal women with breast cancer. METHOD: systematic review guided by the recommendations of the Coc…

OBJECTIVE: The objective of this scoping review is to identify instruments that measure the physical haptic fidelity of procedural skills trainers. INTRODUCTION: Procedural skills trainers have demonstrated beneficial outcomes for clinicians when used to practice and rehearse procedures. Despite this, several design f…

AIM: The aim of the study was to asses the effect of the use of interdental brushes (IDB) in patients as an adjunct to toothbrushing compared with toothbrushing alone or other interdental oral hygiene devices on plaque and the clinical parameters of periodontal inflammation. MATERIAL AND METHODS: MEDLINE-PubMed and th…

Olfactory Reference Disorder is a little explored and widely unknown phenomenon, even research has shown more interest in it during the last years. This review summarizes the existing literature and illustrates its findings with a case history. The databases PubMed, PsychNet, PsychPub, Hogrefe EContent and the Cochrane…