4,953,518 papers found

BACKGROUND AND OBJECTIVE: To describe challenges when extracting and presenting relevant, consistent, and accessible information from systematic reviews. MATERIALS AND METHODS: We systematically selected comparisons and outcomes from 18 Cochrane reviews, evaluated the quality of evidence for each outcome using the GRA…

BACKGROUND: Cardiovascular diseases are the leading cause of death globally. The aim of this overview of systematic reviews was to compare the effectiveness of different pharmacological and non-pharmacological interventions for the primary prevention of cardiovascular disease. METHODS: A structured search of the Cochr…

BACKGROUND: The pressure to publish and the dynamics of academic publishing have increased the prevalence of paper mills, citation sales, plagiarism, and academic post-truth, posing a risk to academic integrity. OBJECTIVE: The aim of this study is to develop and validate the induced citation checklist to measure the r…

INTRODUCTION: This overview aimed to find, assess, and synthesize systematic reviews that compared the cost-effectiveness of interventions designed to improve medication adherence among patients with chronic disease. AREAS COVERED: PubMed, Web of Science, Cochrane Database of Systematic Reviews, and Center for Review…

BACKGROUND: Multiple sclerosis (MS) is one of the major causes of chronic neurologic disability in young adults. OBJECTIVE: To evaluate the effectiveness of information provision interventions for people with MS that aim to promote informed choice and improve patient-relevant outcomes. METHODS: To summarize and to di…

INTRODUCTION: Proton pump inhibitors (PPIs) have evolved to become a frequent treatment option for patients with persistent throat symptoms. The evidence for their use in this context is, however, conflicting. This review assesses the quality of the published systematic reviews and meta-analyses evaluating PPIs in pers…

In recent times many researchers are expressing immense interest in nutraceuticals and functional foods for combating various diseases or abnormal conditions, especially against hypertension (HT). Persistent HT is medically referred to as chronic high blood pressure (BP) and considered to be one of the major risk facto…

INTRODUCTION: The imaging findings of a gastrointestinal stromal tumour (GIST) have been investigated in various studies; however, the features and the pattern of growth of an oesophageal GIST have been described only in a few reports. We present two cases studied by multidetector computed tomography (MDCT) and we revi…

Meta-analyses are seen as representing the pinnacle of a hierarchy of evidence used to inform clinical practice. Therefore, the potential importance of differences in the rigor with which they are conducted and reported warrants consideration. In this review, we use standardized instruments to describe the scientific a…

OBJECTIVES: To compare success, morbidity, patient satisfaction and cost effectiveness of dental implant treatment carried out with and without hyperbaric oxygen (HBO) therapy in irradiated patients. DATA SOURCES: MEDLINE, EMBASE, The Cochrane Oral Health Group's Trials Register, and The Cochrane Central Register of C…

BACKGROUND: The Gut Microbiome (GM) is now a novel target for the treatment of Type 2 Diabetes Mellitus (T2DM), and several systematic reviews and Meta-analyses have provided evidence on the efficacy and safety of modulating GM in T2DM, but this evidence has not been consolidated. OBJECTIVE: The purpose of this scopin…

OBJECTIVES: Hepatic impairment, especially hepatitis, is a growing public health concern in the general population globally. Viral hepatitis, a key driver of liver impairment, remains endemic in many countries across sub-Saharan Africa (SSA). We conducted an umbrella review to assess the prevalence of viral hepatitis a…

BACKGROUND: Loneliness and social isolation are growing public health concerns in our ageing society. Whilst these experiences occur across the life span, 50% of individuals aged over 60 are at risk of social isolation and one-third will experience some degree of loneliness later in life. The aim of this scoping review…

Aim To summarize, critically review, and interpret the evidence related to the systematic reviews on health literacy (HL) amongst type 2 diabetes mellitus (T2DM). Methods The methodology for this study consisted of a systematic review of systematic reviews, using the PRISMA statement and flowchart to select studies, an…

OBJECTIVE: This umbrella review of systematic reviews and meta-analyses evaluates the effectiveness of Solution-Focused Brief Therapy (SFBT) across various populations and settings. METHOD: A total of 25 systematic reviews, including 15 meta-analyses, were analyzed. Reviews were included if they used systematic search…

BACKGROUND: Physical education (PE) classes in schools are considered relevant to implement interventions, especially focused on physical activity. However, evidence overviews on how PE classes contribute to general health (physical, social, affective, and cognitive domains) are still needed. Thus, we summarized eviden…

Cardiovascular disease in patients with systemic lupus erythematosus (SLE) remains one of the most common causes of death and is caused by several factors, including both traditional and disease-specific risk factors. We aimed to systematically appraise the evidence of cardiovascular disease risk factors focusing…