44,697 papers found

BACKGROUND AND PURPOSE: Auriculotherapy for cancer-related fatigue has been investigated in various clinical trials; nonetheless, their conclusions remain inconsistent. In this systematic review and meta-analysis, the efficacy and safety of auriculotherapy for cancer-related fatigue were investigated. METHODS: Randomi…

PURPOSE: Individuals with advanced dementia often endure high symptom burden and receive limited specialized palliative care. Nurses play a central role in delivering end-of-life care, yet the impact of nurse-led interventions remains underexplored. This review synthesizes available evidence on nursing-led approaches,…

BACKGROUND: Mobile health (mHealth) technology is widely used in health care systems globally to improve patients' quality of life and reduce the burden on caregivers. Mobile apps allow users to manage different health-related situations from their homes, such as self-monitoring their symptoms, keeping track of progres…

INTRODUCTION AND AIMS: Denture biofilm is associated with various oral and systemic diseases. Therefore, an effective denture-cleaning method should be adopted by denture wearers. This systematic review aimed to evaluate the efficacy of ultrasonic denture cleaning in reducing plaque quantity and microbial load and chan…

BACKGROUND: Early weight-bearing (EWB) following ankle fracture surgery represents a paradigm shift from traditional rehabilitation protocols. This systematic review and meta-analysis evaluated the efficacy and safety of early versus delayed weight-bearing following operative treatment of ankle fractures. METHODS: We…

The lifestyle and athletic demands of a professional or elite amateur golfer are both physically and mentally challenging. Players need to withstand large forces during the swing, frequently travel between time zones, and often cycle through a variety of training and competition environments for large portions of the c…

Preeclampsia (PE) remains a leading cause of maternal and perinatal morbidity and mortality, with systemic inflammation playing a central role in its pathogenesis. Despite extensive research on inflammatory biomarkers, inconsistencies persist regarding their associations with disease severity and onset. This systematic…

BACKGROUND: The vascular endothelium regulates capillary permeability and inflammation; its function predicts cardiovascular risk and mortality. Low-intensity therapeutic ultrasound (LITUS) may influence endothelial function, but the effects remain uncertain. OBJECTIVE: This systematic review with meta-analysis of cli…

BACKGROUND AND AIM: Trypanosomiasis is a vector-borne parasitic disease with significant implications for animal health and rural livelihoods in Indonesia. Despite surveillance efforts, comprehensive national-level estimates of its prevalence in domesticated animals remain lacking. This study aimed to synthesize the po…

BACKGROUND: Preeclampsia (PE) is a critical complication of pregnancy that affects 3% to 5% of all pregnancies and has been linked to aberrant placentation, causing severe maternal and fetal illness and death. OBJECTIVES: This systematic review aims to elucidate the association of in-utero endocrine-disrupting chemica…

OBJECTIVE: To systematically evaluate the effectiveness of respiratory training interventions in the rehabilitation of patients with rib fractures through a meta-analysis, aiming to provide robust evidence for clinical practice. METHODS: A comprehensive search was conducted in multiple databases (Pubmed, Embase, Web o…

BACKGROUND: Hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHIs) is a new therapy option for anemia in chronic kidney disease (CKD) patients. We aimed to evaluate evidence from randomized controlled trials (RCTs) on HIF-PHIs for anemia in non-dialysis dependent (NDD)-CKD patients. MATERIALS AND METHODS: W…

Skin ageing is influenced by intrinsic factors such as genetics and hormones, as well as extrinsic factors like environmental exposure, ultraviolet (UV) radiation, and diet. These factors lead to biochemical, biological, and structural changes in the skin. Plant-derived compounds with antioxidant and anti-inflammatory…

BACKGROUND: High quality communication between individuals with cancer and their clinicians is a cornerstone of patient-centered oncology practice. Many communication skills training interventions have been evaluated to support either oncology clinicians or patients. However, there is little information regarding the s…

INTRODUCTION: Intestinal constipation is a substantive global health concern, significantly impairing patient quality of life. An emerging view is that the gut microbiota plays a critical role in intestinal function, and probiotics could offer therapeutic benefits. This study aims to consolidate evidence from randomize…

One of the most widespread arboviral diseases in the world, dengue virus disease (DVD) is primarily found in tropical and subtropical regions, affecting 129 countries. The main way that the dengue virus (DENV) spreads is through the bite of a femalemosquito. Symptomatic therapy and supportive care are the primary metho…

OBJECTIVES: This review aims to evaluate the utility of nonmedicated middle meatal packing compared to no packing on synechia formation up to 12 weeks after endoscopic sinus surgery (ESS) for chronic rhinosinusitis (CRS). METHODS: We conducted a systematic review according to Preferred Reporting Items for Systema…

BACKGROUND: Type 2 diabetes mellitus (T2DM) is a major global non-communicable disease, leading to increased morbidity and mortality. Its prevalence in Nigeria is driven by various risk factors. This review assesses the national and regional prevalence and risk factors of T2DM in Nigeria. METHODS: Following PRISMA gui…

BACKGROUND: Adopting lifestyle interventions is pivotal in coronary artery disease (CAD) management and prevention to amplify cardiovascular and mental well-being. This study aims to quantify the effect of mindfulness-based interventions (MBIs) on anxiety, depression and stress in CAD patients. METHODS: A systematic r…

OBJECTIVES: The goal of this systemic review and meta-analysis was to compare the longevity of direct and indirect composite restorations in posterior teeth. DATA: Randomized controlled trials (RCT) investigating direct and indirect composite restorations in permanent posterior teeth. SOURCES: Three electronic databa…