41,029 papers found

BACKGROUND: Many online resources for the life sciences have been developed and introduced in peer-reviewed papers recently, ranging from databases and web applications to data-analysis software. Some have been introduced in special journal issues or websites with a search function, but others remain scattered througho…

OBJECTIVE: The objective of this review is to synthesize the experiences of informal caregivers' feeding practices for children with cancer. INTRODUCTION: Changes in eating among children with cancer impact their nutritional status, leading to several negative outcomes. In addition to interventions given by health car…

MicroRNAs (miRNAs) play important roles in post-transcriptional processes and regulate major cellular functions. The abnormal regulation of expression of miRNAs has been linked to numerous human diseases such as respiratory diseases, cancer, and neurodegenerative diseases. Latest miRNA-disease associations are predomin…

BACKGROUND: The efficacy of induction treatment plus surgery for improving postoperative survival in patients with non-small-cell lung cancer (NSCLC) in stages IIIA-N2 is controversial, especially compared with the combined chemotherapy and radiotherapy. We therefore performed a systematic review and meta-analysis of t…

OBJECTIVE: To review available medical therapies for patients with Cushing disease and to provide a roadmap for their use in clinical practice. METHODS: PubMed searches were performed to identify all of the available published data on medical management of Cushing disease. RESULTS: Medical therapy is usually not the…

Medetomidine is a relatively new sedative analgesic drug that is approved for use in dogs in Canada. It is the most potent alpha2-adrenoreceptor available for clinical use in veterinary medicine and stimulates receptors centrally to produce dose-dependent sedation and analgesia. Significant dose sparing properties occu…

INTRODUCTION: Ethiopia was one of the pioneer countries to implement the World Health Organization's Maternal and Perinatal Death Surveillance and Response (MPDSR) system to accelerate the reduction in maternal and perinatal mortality. However, there has been no systematic evaluation of its implementation in Ethiopia a…

INTRODUCTION: Acromegaly is a quite rare chronic disease caused by the increased secretion of growth hormone (GH) and subsequently insulin - like growth factor 1. Although cardiovascular diseases remains the most common cause of mortality among acromegalic patients, increased prevalence of malignant and benign neoplasm…

Obsessive-compulsive disorder (OCD) is a psychiatric condition characterized by intrusive and unwilling thoughts (obsessions) giving rise to anxiety. The patients feel obliged to perform a behavior (compulsions) induced by the obsessions. The World Health Organization ranks OCD as one of the 10 most disabling medical c…

STATEMENT OF PROBLEM: Various factors are responsible for sleep bruxism; however, whether the dopaminergic agonist group of drugs is effective in the treatment of sleep bruxism is unclear. PURPOSE: The purpose of this systematic review was to evaluate the effect of the dopaminergic agonist group of drugs in controllin…

The objective of this study was to assess the efficacy of botulinum toxins on bruxism. Electronic databases (PubMed, Embase and Science Citation Index), websites (Cochrane Central Register of Controlled Trials and ClinicalTrials.gov) and the literature database of SIGLE (System for Information on Grey Literature in Eur…

"Ring-like" intracranial aneurysms-historically described as "" or ""-represent a rare configuration in which a central thrombus coexists with a circumferential mural flow ring. Traditionally considered a radiologic curiosity, this morphology likely reflects a shear-driven hemodynamic state rather than a stable organiz…

ABSTRACT: The main purpose of this review is to compare and analyze the results of the main PresbyLASIK approaches; central and peripheral. SUMMARY: A comprehensive research was conducted in PUBMED using keywords like "presbyopia correction", "PresbyLASIK", "Corneal multifocality", "Laser blended vision". We reviewed…

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by neuronal degeneration and inflammation in the nerves. The role of the immune system has been concentrated by researchers in the etiopathogenesis of the disease. Given the inhibitory roles of regulatory T cells (Tregs), it is expected t…

AIM: Reference data analysis and visualization methods were applied to identify current knowledge mapping methods in the neuroimmune modulation research field. METHODS: A comprehensive search of publications within the field of neuroimmune modulation in the Web of Science Core Collection database and PubMed from 2005-…

The health informatics profession in Bosnia and Herzegovina has relatively long history. Thirty five years from the introduction of the first automatic manipulation of data, thirty years from the establishment of Society for Medical Informatics BiH, twenty years from the establishment of the Scientific journal "Acta In…

Hematologic disorders and malignancies are commonly encountered in children. The central nervous system is affected by many benign and malignant hematological diseases. Neurologic findings may occur due to central involvement of hematological disease or neurotoxic effects of treatment during the disease. At all these s…

Severe dengue outbreaks (DOs) affect the majority of Asian and Latin American countries. Whether all DOs always occurred in sub-tropical and tropical areas (STTA) has not been verified. We downloaded abstracts by searching keywords "dengue (MeSH Major Topic)" from Pubmed Central since 1950, including three collections:…

OBJECTIVE: This study collects what is known about the inheritance underpinnings of syndromic and non-syndromic polydactylies and highlights dactyly presentations with unknown genetic roots. This review summarizes the current information and genetics-enhanced understanding of polydactyly. BACKGROUND: There is a freque…