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Abstract not available
Boyle Jennifer S, Bechtel Laura K, Holstege Christopher P·Scandinavian journal of trauma, resuscitation and emergency medicine
BACKGROUND: Clinicians are often challenged to manage critically ill poison patients. The clinical effects encountered in poisoned patients are dependent on numerous variables, such as the dose, the length of exposure time, and the pre-existing health of the patient. The goal of this article is to introduce the basic c…
Zeng Xiantao, Zhang Yonggang, Kwong Joey S W, +5 more·Journal of evidence-based medicine
OBJECTIVE: To systematically review the methodological assessment tools for pre-clinical and clinical studies, systematic review and meta-analysis, and clinical practice guideline. METHODS: We searched PubMed, the Cochrane Handbook for Systematic Reviews of Interventions, Joanna Briggs Institute (JBI) Reviewers Manual…
Teixeira L, Avery R K, Iseman M, +4 more·American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Nontuberculous mycobacteria are increasingly encountered pathogens in organ transplant recipients. We report the first case of human disease attributed to Mycobacterium llatzerense that occurred in a liver transplant recipient in the midwestern United States who developed pneumonia and describe the treatment of this pa…
Simon Mireille, Bioulac-Sage Paulette, Trillaud Hervé, +1 more·Acta oncologica (Stockholm, Sweden)
Abstract not available
Altman D G·Statistics in medicine
I review some areas of medical statistics that have gained prominence over the last 5-10 years: meta-analysis, evidence-based medicine, and cluster randomized trials. I then consider several issues relating to data analysis and interpretation, many relating to the use and misuse of hypothesis testing, drawing on recent…
Gonai Shiro, Miyoshi Takahiro, da Silva Lopes Katharina, +1 more·The American journal of emergency medicine
OBJECTIVE: This study aims to provide a comprehensive review of the current evidence on accurate and rapid diagnostic methods, effective and safe shoulder dislocation reduction techniques, pharmacological treatment, and post-reduction care for acute anterior shoulder dislocation in the emergency department (ED). METHO…
Sarich Peter, Gao Shuhan, Zhu Yining, +2 more·Addiction (Abingdon, England)
BACKGROUND AND AIMS: Systematic reviews of the relationship between alcohol consumption and all-cause mortality have reported different relative risk (RR) curves, possibly due to the choice of reference group. Results have varied from 'J-shaped' curves, where low-volume consumption is associated with reduced risk, to m…
Conneely Mairéad, Leahy Siobhán, Dore Liz, +4 more·BMC geriatrics
BACKGROUND: Population ageing is increasing rapidly worldwide. Older adults are frequent users of health care services including the Emergency Department (ED) and experience a number of adverse outcomes following an ED visit. Adverse outcomes include functional decline, unplanned hospital admission and an ED revisit. G…
Azar Farbod Ebadifard, Azami-Aghdash Saber, Pournaghi-Azar Fatemeh, +4 more·BMC health services research
BACKGROUND: Due to extensive literature in the field of lung cancer and their heterogeneous results, the aim of this study was to systematically review of systematic reviews studies which reviewed the cost-effectiveness of various lung cancer screening and treatment methods. METHODS: In this systematic review of syste…
Layton Deborah, Porta Antonella, Patel Dony, +8 more·Pharmaceutical medicine
High-quality pharmacoepidemiological research is essential for credible real-world evidence (RWE). This expert consensus-based review explores how pharmaceutical Quality Management Systems (QMS) developed for studies using primary data collection (e.g., clinical trials, registries) can be adapted to support studies uti…
Smith Ellesha A, Cooper Nicola J, Sutton Alex J, +2 more·BMC public health
BACKGROUND: The complexity of public health interventions create challenges in evaluating their effectiveness. There have been huge advancements in quantitative evidence synthesis methods development (including meta-analysis) for dealing with heterogeneity of intervention effects, inappropriate 'lumping' of interventio…
Casteli Christiane Pereira Martins, Mbemba Gisèle Irène Claudine, Dumont Serge, +5 more·Systematic reviews
BACKGROUND: Home-based hospitalization (HBH) offers an alternative delivery model to hospital care. There has been a remarkable increase in pilot initiatives and deployment of this model to optimize services offered to a population with a variety of progressive and chronic diseases. Our objectives were to systematicall…
Demeke Ababo, Kassa Getu, Gebrie Habtamu, +9 more·BMC infectious diseases
BACKGROUND: Malaria is a protozoan disease caused by species of plasmodium. Despite the expanded control efforts, it continues to threaten vulnerable groups in Ethiopia. It remains a leading cause of illness and death, particularly among pregnant women, children, and migrant populations. Though previous studies report…
Hoe Connie, Weiger Caitlin, Minosa Marela Kay R, +3 more·Globalization and health
BACKGROUND: Noncommunicable diseases contribute to over 70% of global deaths each year. Efforts to address this epidemic are complicated by the presence of powerful corporate actors. Despite this, few attempts have been made to synthesize existing evidence of the strategies used to advance corporate interests across in…
Horvath Andrea Rita, Pewsner Daniel·Clinica chimica acta; international journal of clinical chemistry
BACKGROUND: Systematic reviews and meta-analyses are generally accepted to represent the highest level of evidence, and are a cornerstone in practising evidence-based medicine. So far, these efforts have been largely confined to the evaluation of the efficacy and effectiveness of therapeutic and preventive intervention…
Duarte Marta Alves, Neves João Albernaz, Caçador Madalena, +1 more·International dental journal
OBJECTIVES: To evaluate and synthesise the current evidence on the efficacy of laser-activated irrigation in endodontics, with a focus on microbial reduction, postoperative outcomes, and its potential as an adjunct to conventional irrigants. METHOD: A comprehensive search was conducted to identify relevant systematic…
Cierco Jimenez Ramon, Lee Teresa, Rosillo Nicolás, +4 more·BMC medical research methodology
BACKGROUND: Within evidence-based practice (EBP), systematic reviews (SR) are considered the highest level of evidence in that they summarize the best available research and describe the progress in a determined field. Due its methodology, SR require significant time and resources to be performed; they also require rep…
Cai Qian, Chen Dan-Qi, Wang Hua, +4 more·BMC pregnancy and childbirth
BACKGROUND: Kangaroo mother care (KMC) is an evidence-based intervention that reduces morbidity and mortality in preterm infants. However, it has not yet been fully integrated into health systems around the world. The aim of this study is to provide a cogent summary of the evidence base of the key barriers and facilita…
Lee Sangyeob, Yoo Jun-Il, Kang Yang-Jae·Journal of orthopaedic surgery and research
BACKGROUND: Femoral head osteonecrosis (FHON) is a worldwide challenging clinical topic. Steroid use is one of the main etiologies of FHON. There are several genetic variants associated with FHON. Therefore, the purpose of this umbrella review was to provide a comprehensive summary of a meta-analysis and systematic rev…