11,609,670 papers found

OBJECTIVE: Laser-based tissue perfusion monitoring techniques have been increasingly used in animal and human research to assess blood flow. However, these techniques use arbitrary units, and knowledge about their comparability is scarce. This study aimed to model the relationship between laser speckle contrast imaging…

BACKGROUND: Human papillomavirus (HPV) vaccines are a critical strategy in the prevention of cervical cancer, especially in countries like Zimbabwe where cervical cancer screening rates are low. In Zimbabwe, cervical cancer is the leading cause of cancer-related deaths in women but the HPV vaccine is not yet widely ava…

OBJECTIVE: Research emphasises the critical role of blood-brain barrier (BBB) integrity in psychiatric disorders. This study aimed to investigate the relationship between serum Zonula occludens protein - 1 (ZO-1) and serum occludin levels, which are blood brain barrier markers, and serum oxLDL levels, which are known t…

OBJECTIVE: Hereditary cancer syndromes constitute 5-10% of all cancers. The development of next-generation sequencing technologies has made it possible to examine many hereditary cancer syndrome-causing genes in a single panel. This study's goal was to describe the prevalence and the variant spectrum using NGS in indiv…

Karst water quality is one of the most important environmental issues in karst areas. The study's purpose was to investigate dissolved heavy metal pollution and health risk assessment in karst water basins around mines. River water and groundwater samples were analyzed by principal component analysis, correlation analy…

Mutant alleles of, a gene that encodes a putative calcium-dependent cell-adhesion glycoprotein with multiple cadherin-like domains, are responsible for both recessivenonsyndromic hearing loss (NSHL) and Usher syndrome 1D (). The encoded protein cadherin 23 (CDH23) plays a vital role in maintaining normal cochlear and r…

BACKGROUND: Differentiated thyroid cancer (DTC) generally has a favorable outcome, but some patients develop local recurrence and/or distant metastases and ultimately die of their disease. Molecular markers that accurately predict tumor behavior are lacking. This study's aim was to ascertain the role of cell cycle regu…

We investigated the effects of pepsin/hydrochloric acid and bile acids on eustachian tube function and eustachian tube mucosa in 40 Sprague-Dawley rats. The animals were randomly assigned to groups of 10: one group received pepsin/hydrochloric acid (pepsin/HCl group), another received human bile (human bile group), a t…

Parental embodied mentalizing is about how parents show with their body that they hold in mind their infants' mind. The main study's aim was to explore what influences fathers' embodied mentalizing. A random sample of 200 fathers and their 12-month-old infants were drawn from a large longitudinal, population-based data…

OBJECTIVE: The Generalized Anxiety Disorder-7 (GAD-7) and Patient Health Questionnaire-9 (PHQ-9) are two widely used instruments for assessing anxiety and depression, respectively, but no studies have examined their psychometric properties among individuals with substance use disorders. This study's objectives were to…

BACKGROUND: Given the persistent, complex, and diverse health needs of chronic disease patients, their health literacy and active participation in the process of primary health service delivery has gained increasing attention. This study aimed to identify the potential profiles of patient health literacy, examine the s…

Nephrolithiasis affects approximately 10% of North Americans, placing a significant burden on health care systems. This study evaluates the effectiveness of a novel, virtual Small Acute Ureteral Stone (SAUS) protocol for managing ureteral stones ≤5 mm, aiming to optimize resource utilization and patient care.A r…

The purpose of this study was to investigate whether the relationship between mental health and well-being among Chinese nurses could be mediated by factors such as night shift frequency and psychological flexibility. A total of 421 nurses were selected from 10 Grade secondary public hospitals in Shanghai, China. The 1…

Resilience, defined as the ability to adapt and recover from adversity, plays a critical role in mitigating psychological distress, particularly in high-stress environments like medical education. This study investigates the association between resilience and the second-to-fourth digit length ratio (2D:4D), a proposed…

Over the past few years, there has been a growing awareness of the extent and consequences of sexual assault. Sexual assault has long-term consequences for the survivor's mental health and brings into question the resources available to survivors for dealing with the consequences of the assault. The positive effects of…

Crisis supporters can experience numerous stressors in their role that can impact their own mental well-being. The area remains underexplored in research, particularly relating to substance use, and new trends in the role such as working remotely or the impact of providing chat-based support.This study identifies crisi…

Increasingly, studies compare risk and protective factors for involvement in violent and nonviolent terrorist behaviors. This exploratory study investigates whether this distinction is sufficient, or whether it should be disaggregated further into more granular terrorist roles and behaviors. Using data on 404 referrals…

Ensuring stable blood glucose (BG) levels within the norm is crucial for potential long-term health complications prevention when managing a chronic disease like Type 1 diabetes (T1D), as well as body weight. Therefore, accurately forecasting blood sugar levels holds significant importance for clinicians and specific u…

BACKGROUND: Robotic devices are known to provide pivotal parameters to assess motor functions in Multiple Sclerosis (MS) as dynamic balance. However, there is still a lack of validation studies comparing innovative technologies with standard solutions. Thus, this study's aim was to compare the postural assessment of fi…

BACKGROUND: One method for treating adolescent idiopathic scoliosis (AIS), which is characterized by abnormal spinal alignment in the coronal, sagittal, and rotational planes, is surgical correction. The two surgical techniques most typically used to correct spine alignment are simple rod derotation (SRD) and direct ve…