98,306 papers found

BACKGROUND: It has been known since many years that scoliosis can continue to progress after skeletal maturity: the rate of progression has shown to be linear, and it can be used to establish an individual prognosis. Once there is progression there is an indication for treatment: usually it is proposed a surgical one.…

OBJECTIVE: Revision total hip arthroplasty (THA) imposes physical and financial burdens on patients and depletes limited medical resources. Causes for revision THAs can change as technology changes. Therefore, understanding contemporary causes is essential for clinical decision-making. We analyzed causes and trends ass…

BACKGROUND: Because of improved long-term survival after heart transplantation (HTx), late graft pathologies such as valvular disease or cardiac allograft vasculopathy (CAV) might need surgical intervention to enhance longer survival and ensure quality of life. To this date, there exist no guidelines for indication of…

BACKGROUND: The effect of the model for end-stage liver disease (MELD) system on the post-transplant survival of patients with hepatocellular carcinoma (HCC) has not been fully elucidated. Our objective is to review the results of liver transplantation (LT) for HCC at the Massachusetts General Hospital over a period of…

INTRODUCTION: Improvements in immunosuppressive therapy have significantly changed results of organ transplantation. The aim of this study was to review the causes of mortality among our renal transplant population. METHODS: This study population included 750 patients who underwent kidney transplantation between 1970…

INTRODUCTION: The aim of this study was to assess the outcome of surgery for rectal cancer in patients 80 years of age or more. METHODS: A retrospective study of 29 patients older than 80 years, who presented in our institution between 1997 and 2001 with the diagnosis of rectal adenocarcinoma, was undertaken. RESULTS…

The Hancock II bioprosthesis was used for heart valve replacement in 614 patients from 1982 to 1990. Aortic valve replacement (AVR) was performed in 376 patients, mitral valve replacement (MVR) in 195, and aortic and mitral valve replacement (DVR) in 43. The mean age was 62.7 years, and 78% of all patients were in New…

BACKGROUND: A growing body of evidence indicates that there are a substantial number of children who report asthma-like symptoms and are not diagnosed with asthma. However, there is little information on the health consequences of asthma-like symptoms for children with these symptoms and no asthma diagnosis. OBJECTIVE…

BACKGROUND: Tine-based leadless pacemakers have been commercially implanted over the last 10 years. Retrieval of older devices is rarely discussed and based on rare case reports only. METHODS: A retrospective review of an extraction case of a Micra AV leadless pacemaker was performed. Internal Review Board approval wa…

Peyronie's disease is postulated to be initiated by repetitive minor traumas to the fully or partially erect penis. We investigated Peyronie's disease prospectively in cases treated for penile fracture (PF) within the last 20 years. Medical records of 63 cases treated for PFs were reviewed. Subjects were required to se…

The current locations of objects are informative about the temporal order of past events. For example, by simply examining the locations of objects underground, geologists and historians can determine their relative ages. In three experiments, we explored the development of this ability to infer time from structure in…

Over the last decade, MALDI-MS imaging has been used by researchers to explore areas of proteomics, lipidomics and metabolomics in samples of clinical origin for both targeted and global biomarker analysis. Numerous technological advancements in MS and clinical tissue MS imaging have been accomplished; hence, in this a…

Bronchopulmonary dysplasia is a chronic lung disease associated with premature birth and characterized by early lung injury. In this review we discuss some pitfalls, problems, and progress in this condition over the last decade, focusing mainly on the last 5 years, limited to studies in human neonates. Changes in the d…

Blood is a precious and vital resource in medicine. Its importance in maintaining human life is second only to the oxygen it transports. Nearly 300,000 blood product transfusions occurred in Kentucky last year. While donor attrition from the pool is inevitable, recruiting efforts have resulted in an overall stable dono…

6 new factors and 2 specificities 8L (A8-like) and 6L (B6-like) are described in sheep, in addition to the previously described 11 factors. 3 new factors are the products of three alleles (C14, C15, C17) at a third OLA-C locus of the OLA major histocompatibility complex, closely linked to the OLA-A and B loci. 2 other…

In this study we have determined the incidence of hepatocellular carcinoma (HCC) development in primary biliary cirrhosis (PBC) and its effects on patient survival. Six hundred and sixty seven patients with liver histology compatible with or diagnostic of PBC were seen over a 20-year period. Two hundred and seventy thr…

OBJECTIVE: To assess the mid-term patient outcome after operative treatment of a displaced intra-articular calcaneal fracture according to Palmer. MATERIALS AND METHODS: Eighteen operatively treated intra-articular fractures of the calcaneus in 16 patients (nine males, seven females) were retrospectively reviewed. Mea…

INTRODUCTION: High incidence of HIV infection among adolescent girls and young women (AGYW) has been attributed to the numerous and often layered vulnerabilities that they encounter including violence against women, unfavourable power relations that are worsened by age-disparate sexual relations, and limited access to…

STUDY DESIGN: Retrospective study. OBJECTIVE: To analyze the various anatomical parameters that influence segmental stability in patients suffering from lumbar intra spinal cysts (LISCs) and to determine the outcome of microscopic unilateral laminotomy and cystectomy. METHODS: All patients that were surgically manage…

BACKGROUND: Acute flaccid paralysis surveillance (AFP) is an essential strategy of the WHO's Polio Eradication Initiative. This is the first study conducted to estimate the incidence, etiology, distribution, and surveillance performance of AFP in Iraq. METHODS: Surveillance data about the AFP cases under the age of 15…