Chronic subthalamic nucleus stimulation reduces medication requirements in Parkinson's disease.
Moro E, Scerrati M, Romito L M, +3 more·Neurology
OBJECTIVE: To reduce antiparkinsonian medication in parkinsonian patients with bilateral high frequency subthalamic nucleus (STN) stimulation. BACKGROUND: Parkinsonian syndromes are characterized by hyperactivity of the STN. Preliminary data indicate that functional inactivation of the STN may reduce the requirement f…