98,306 papers found

Worldwide incidence of malignant melanoma has been constantly increasing during the last years. Surgical excision is effective when primary tumours are thin. At later disease stages patients often succumb, due to failure of metastasis control. Therefore, great efforts have been made to develop improved strategies to tr…

BACKGROUND: The SALTO total ankle prosthesis is a noncemented mobile bearing anatomic design characterized by dual Ti-HA coating. This study reviews our results with this prosthesis. MATERIALS AND METHODS: Between 2001 and 2007, 413 consecutive SALTO prostheses were implanted in our institution in 215 women and 198 me…

INTRODUCTION: The aim of this article is a retrospective analysis of the results of three methods used for the repair of pectus excavatum between 1991 and 2012. MATERIAL AND METHODS: 508 patients were operated on at the Department of Paediatric Surgery of the Second Faculty of Medicine, Charles University, and the Tea…

IMPORTANCE: Transplantation has transformed into a burgeoning field that is rapidly evolving to optimize organ distribution and survival outcomes. The years since 2012 (the last comprehensive study) have seen changes in transplantation, such as advances in immunotherapy and novel indices, that necessitate an updated an…

Eighty-three consecutive patients (38 men, 45 women) underwent colectomy and ileorectal anastomosis (IRA) for Crohn's colitis between 1960 and 1988. The mean age at the time of IRA was 28.5 years after a mean interval of four years from diagnosis. At the time of IRA, 31 patients had proctitis, while 25 had perianal dis…

BACKGROUND: In the last few years laparostomy has become an even more useful option for the surgeon due to the development of the experience in the critical abdominal trauma and in the severe surgical urgencies as PANE and peritonitis with the introduction of Damage Control as surgical strategy to prevent the abdominal…

Multiple primary cancers in 30,386 consecutive autopsy cases from 1883 to 1982 in Tokyo University Hospital and 273,796 registered autopsy cases from 1974 to 1982 in Japan were examined. The frequency of multiple primary cancers among all cancers at Tokyo University Hospital was less than 0.5% until 1940. From 1960, it…

As a part of Marmara Sea, Izmit Bay (Turkey) has been one of the most polluted sites in the region for the last 25 years. On 17 August 1999, a powerful earthquake along the North Anatolian Fault struck the eastern part of the Marmara region including Izmit Bay. The earthquake destroyed many coastal cities. The Bay was…

BACKGROUND: The magnitude of pre-transplant a-fetoprotein (AFP) changes has been advocated to be a superior predictor of hepatocellular cancer (HCC) recurrence following liver transplantation. The aim of this study was to compare AFP dynamics and last pre-transplant AFP as risk factors for post-transplant HCC recurrenc…

OBJECTIVES: To determine the functional trajectory in the last year of life in end-stage renal disease managed without dialysis. DESIGN: Longitudinal cohort study of functional status over time and toward death. SETTING: Three renal units in the United Kingdom. PARTICIPANTS: Patients with Stage 5 chronic kidney dise…

Modern world is hostile to sleep and by its achievements it disturbs our hereditary biological rhythm. About 80% of all the cases of hyposomny are caused by emotional disturbances in the broadest sense. Somnipathy in a prison shows of course considerable characteristics, although here, too, we can find the same problem…

Dust dominates extraterrestrial flux on the earth (30,000 tonnes/yr), however only ~5% of the cosmic dust survives atmospheric entry which is basically in two forms: melted and unmelted. Melted micrometeorites undergo transformational changes due to heating during atmospheric entry which obliterate evidences regarding…

The paper describes the history of the Russian Research Center of Roentgenology and Radiology set up 90 years ago, the main advances of the researchers of the Institute in roentgenology and radiodiagnosis in historical perspective--from the last century up to the present day. It gives a brief list of the most important…

The amino alcohol serinol (2-amino-1,3-propanediol) has become a common intermediate for several chemical processes. Since the 1940s serinol was used as precursor for synthesis of synthetic antibiotics (chloramphenicol). In the last years, new scopes of applications were discovered. Serinol is used for X-ray contrast a…

Although crystallographic studies of membrane proteins have progressed in the last 5 years, the field still remains challenging with several severe bottlenecks. The chapter focuses on the crystallization and describes two approaches, the classical vapor diffusion method and the more recent use of lipidic phases. Genera…

The ACR has published more than 160 guidelines to assist radiologists in quality practice. One of the most controversial guidelines is on communication, first adopted more than a decade ago. This guideline is coming up for reconsideration and perhaps revision by the ACR Council at the ACR AMCLC in Washington, DC, in Ma…

Much of what is know about quorum sensing has come from the study of marine biology. The original description of the phenomenon was based on the study of marine bacteria and the luminescent pathway. More recently, aquatic organisms have been found to inhibit bacterial fouling of surfaces by blocking signaling pathways…

Aneurysms of splanchnic arteries represent an uncommon but important vascular disease, which many times presents itself as clinical emergency and often results in death. 11 patients with splanchnic aneurysms were treated in our Department during the last 15 years. These aneurysms were located in 5 cases in splenic arte…

Eosinophilic cholecystitis is a rare form of cholecystitis. Histologically, it is characterized by a dense, transmural leukocyte infiltrate composed of more than 90% eosinophils. The etiology remains obscure, although it had been associated with allergies, parasites, hypereosinophilic syndromes, eosinophilic gastroente…

As a health care professional for many years, Ivan Hanson was an advocate of quality health care and the caring component. As a health care consumer during his nearly 5-year struggle with cancer, he had ample opportunity for thoughtful reflection about this same care and caring. During the last stage of his illness he…