5,083,888 papers found

BACKGROUND: Decisionmakers and guideline developers demand rapid syntheses of the evidence when time sensitive evidence-informed decisions are required. A potential trade-off of such rapid reviews is that their results can have less reliability than results of systematic reviews that can lead to an increased risk of ma…

OBJECTIVES: To investigate the use, challenges and opportunities associated with using patient-reported outcomes (PROs) in studies with patients with rare lysosomal storage diseases (LSDs), we conducted interviews with researchers and health technology assessment (HTA) experts, and developed the methods for a systemati…

INTRODUCTION: Antipsychotics are commonly used in adult palliative care practice due to their multiple therapeutic indications. However, the available evidence regarding their use, effectiveness and safety in this context remains heterogeneous, and no comprehensive overview of their use across all palliative indication…

BACKGROUND: Delays in cancer treatment can result in tumor growth, increased clonal heterogeneity, upstaging, increased symptoms, organ damage, increased psychological distress, and worse clinical outcomes. Evidence supported guidelines for treatment timeliness exist in many cancers, but not for multiple myeloma (MM) t…

OBJECTIVE: The objective of this review is to identify and map the available literature on how allied health assistants are utilized in Australia. INTRODUCTION: Allied health assistants have the potential to increase service delivery output for the allied health workforce; however, barriers to successful implementatio…

INTRODUCTION: Research indicates that older hospitalised individuals are more susceptible to hospital adverse events (AEs). Frailty is a syndrome marked by increased vulnerability, sudden and severe health changes and the risk of adverse outcomes. The majority of the available research puts a limited emphasis on those…

BACKGROUND: In recent decades, the literature on global partnerships in nursing and midwifery education, to enhance the quality of education and produce competent graduates in the labor market, is on the rise in Africa. However, there is a gap regarding the best practices and barriers in the African context. This syste…

Intradialytic hypotension (IDH) is common in hemodialysis patients and can lead to several complications. Risk factors for IDH include demographic characteristics, comorbidities, dialysis procedure factors, and so on. Clinical studies on predictive models for dialysis-induced hypotension have shown inconsistent results…

INTRODUCTION: Currently, literature on spiritual health remains limited. Even more so, literature on spiritual health remains limited in Canada. This is exacerbated by the fact that spiritual health is a term that remains widely contested with no concrete definition. Meanwhile, the semantic connection between "religion…

OBJECTIVE: The objective of this scoping review is to understand the current body of knowledge regarding deprescribing in adults aged 60 years or older in acute care settings, including the deprescribing activities that are being undertaken, and the feasibility, challenges, and outcomes of the practice. INTRODUCTION:…

OBJECTIVE: This scoping review will aim to map the existing academic literature on simulation-based activities that are designed with and delivered for health professionals in geographically rural and remote contexts in high-income countries. INTRODUCTION: Simulation-based health care activities are implemented in hea…

BACKGROUND: There is a call for gathering more evidence on the effectiveness of telerehabilitation in stroke. In particular, a previous systematic review reported substantial variability in the types of technologies used in telerehabilitation interventions. The purpose of this study will be to summarize and synthesize…

INTRODUCTION: Cancer, a life-threatening chronic disease, is the leading cause of death in Korea, accounting for 27% of all deaths in 2020. Due to advancements in medical technology and early detection of cancer in Korea, the 5-year relative survival rate reached 70.7% (2015-2019), highlighting remarkable progress over…

OBJECTIVE: The objective of this scoping review is to understand the scope and nature of evidence in relation to the ethical issues that arise when conducting health research with military personnel. INTRODUCTION: Ethical obligations in human research have been debated for centuries. Historically, research conducted w…

OBJECTIVE: The objective of this scoping review is to identify the frameworks, guidelines, and models used to develop and deliver justice, equity, diversity, inclusion (JEDI), and anti-oppression (AO) principles in mandatory, entry-level health care professional program curricula (EHCPPC). A secondary objective will be…

INTRODUCTION: Culture is highlighted in previous research as important in encounters where health professionals and children do not share a language or culture. In these encounters, culture is described as mainly related to the child, whereas the health professionals' understanding of their own culture as impacting the…

INTRODUCTION: Infertility adversely affects the sexual reproductive health and overall quality of life of people. Recent estimates show that about one in six people (both men and women) experience infertility in their lifetime. This scoping review will, therefore, map the existing evidence on traditional management of…

OBJECTIVE: This review will evaluate the effectiveness of natural orifice transluminal endoscopic surgery (NOTES)/hybrid NOTES versus traditional surgical techniques in the management of diverticular disease. INTRODUCTION: Diverticular disease can have a significant impact on a patient's quality of life, especially th…

INTRODUCTION: COVID-19 disease was declared as a pandemic by WHO since March 2020 and can have a myriad of clinical presentations affecting various organ systems. Patients with COVID-19 are known to have an increased risk of thromboembolism, including cardiovascular, pulmonary and cerebral ischaemic events. However, an…

INTRODUCTION: This review aims to explore the existing literature about the virtue of helping others and its association with youth mental health. Mental health of youth is rooted in their social environment. Helping others or engaging in prosocial behavior are activities that youth may participate in. The notion of he…