4,999,516 papers found

Idiopathic facial palsy is the most common disease of the VII cranial nerve. There are many treatments to facilitate recovery from this condition: pharmacological, surgical, rehabilitative, but the effectiveness of some of these treatments, especially the latter, is still under discussion. The purpose of this umbrella…

BACKGROUND: sustainability of population diet is a public health concern: the high price of healthy food is one of the main causes of diet-related health problems. The aim of this study is to synthesize the evidence produced by systematic reviews that evaluated the effectiveness of decreasing healthy food prices to imp…

In this series we address important topics for emergency clinicians who either participate in research as part of their work, or use the knowledge generated by research studies. Emergency clinicians are routinely in the position of applying new evidence in clinical practice. With an ever-increasing volume of evidence g…

OBJECTIVES: We audited a selection of systematic reviews published in 2013 and reported on the proportion of reviews that researched for unpublished data, included unpublished data in analysis and assessed for publication bias. DESIGN: Audit of systematic reviews. DATA SOURCES: We searched PubMed and Ovid MEDLINE In-…

INTRODUCTION: The use of search filters (e. g. for study types) facilitates the process of literature searching. Regional limits might be helpful depending on the research question. Regional search filters are already available for some regions, but not for Germany. Our aim is to give an overview of applied search stra…

This article is the second article in a series of six focusing on systematic reviews in animal agriculture and veterinary medicine. This article addresses the strengths and limitations of study designs commonly used in animal agriculture and veterinary research to assess interventions (preventive or therapeutic treatme…

BACKGROUND: Functional Neurological Disorder (FND) is among the most common reasons for neurology outpatient referrals, characterized by disabling motor, sensory, speech, and dissociative symptoms. It poses diagnostic and therapeutic challenges, often requiring multidisciplinary management and a biopsychosocial framewo…

Melatonin is increasingly used to treat sleep disturbances, yet its overall efficacy remains unclear due to variability in existing evidence. This scoping review aimed to synthesize systematic reviews with meta-analyses assessing the effects of exogenously administered melatonin on sleep quality in humans. Seven databa…

BACKGROUND: This systematic review and meta-analysis aimed to evaluate existing evidence on the relationship between diagnostic and treatment intervals and outcomes for colorectal cancer. METHODS: Four databases were searched for English language articles assessing the role of time before initial treatment in colorect…

The aim of this systematic review of reviews was to synthesise the evidence on factors influencing the implementation, sustainability and scalability of food retail interventions to improve the healthiness of food purchased by consumers. A search strategy to identify reviews published up until June 2020 was applied to…

The aim of the systematic review described in this article was to synthesize available high-quality evidence on the outcomes of noninstitutional child maltreatment across the life span. A systematic review of previous systematic reviews and meta-analyses was conducted. Ten databases were searched. One hundred eleven pa…

INTRODUCTION: Rapid reviews (RR), using abbreviated systematic review (SR) methods, are becoming more popular among decision-makers. This World Health Organization commissioned study sought to summarize RR methods, identify differences, and highlight potential biases between RR and SR. METHODS: Review of RR methods (K…

OBJECTIVES: To strengthen the evidence-base for policy and practice for support of children outside of family care requires effective, efficient and sustainable mechanisms for monitoring and evaluation. Toward that end, two core questions guided a systematic review of evidence: What strategies are appropriate for monit…

STUDY DESIGN: Descriptive method guidelines. OBJECTIVES: To help reviewers design, conduct, and report reviews of trials in the field of back and neck pain. SUMMARY OF BACKGROUND DATA: In 1997, the Cochrane Collaboration Back Review Group published method guidelines for systematic reviews. Since its publication, new…

OBJECTIVE: This umbrella review synthesized high-level evidence on the clinical longevity and failure patterns of direct restorative materials, including conventional composites, bulk-fill resins, ormocer-based composites, and glass ionomer cements (GIC/RMGIC) used in posterior restorations and non-carious cervical les…