98,302 papers found

OBJECTIVES: To retrospectively analyse and report the utilisation of red blood cell (RBC) transfusion in a tertiary otolaryngology, head and neck centre in the United Kingdom. BACKGROUND: Twenty-seven per cent of RBC transfusions were for surgical indications in a 2014 England and North Wales survey. Currently, there…

Natural killer (NK) cell therapy began decades ago with administration of small doses of minimally-characterized cells known as cytokine-induced or lymphokine-activated killer cells (CIK or LAK, respectively). Methods and conditions that enabled the broad adoption of T cell therapies have often been less effective for…

Central Sahel is affected by a reinforcement of rainfall since the beginning of 1990s. This increase in rainfall is affected by high inter-annual variability and is characterized by extreme rain events causing floods of unprecedented magnitude. However, few studies have been carried out on these extreme events. Moreove…

UNLABELLED: Navigating novel, unpredicted service disruptions can be complex and unparalleled. To effectively handle service interruptions, board certified behavior analysts (BCBAs®) must make sound clinical decisions, comply with the Behavior Analyst Certification Board's Ethics Code for Behavior Analysts (2020a)…

PURPOSE OF REVIEW: Surgical training has dramatically changed over the last decade. It has become not only the way to prepare surgeons for their everyday work, but also a way to certify their skills thus increasing patient safety. This article reviews advances in the use of machine learning and artificial intelligence…

Induced pluripotent stem cells (iPSCs) represent today an invaluable tool to create disease cell models for modeling and drug screening. Several lines of iPSCs have been generated in the last 7 years that changed the paradigm for studying diseases and the discovery of new drugs to treat them. In this article we focus o…

Polycyclic aromatic hydrocarbons (PAHs) are a family of contaminants that consist of two or more aromatic rings fused together. Soils contaminated with PAHs pose significant risk to human and ecological health. Over the last 50 years, significant research has been directed towards the cleanup of PAH-contaminated soils…

INTRODUCTION: The key to heal primary hyperparathyroidism is to find the hyper functioning parathyroid gland(s). Promoting this the perioperative isotope guided localization technique is worldwide used in the last years. AIM: Authors use this method since February, 2000. They present their experiences. METHODS: At 12…

PURPOSE: During the last 10 years there has been controversy in the approach to severe hypospadias. Many pediatric urologists have elected to perform a 2-staged procedure to minimize complication rates and improve cosmesis. We continued to perform a single staged repair using the Hodgson XX or Koyanagi technique for ev…

The risk of breast cancer of oral contraceptive (OC) use in 1423 women from families with hereditary/familial breast cancer recruited through a cancer family clinic was analyzed in a matched case-control study. Ninety-eight women tested positive for a BRCA1 mutation. Hazard ratio for ever use of OCs adjusted for other…

Over the last 6 years there has been a decline in the incidence of measles in Cape Town. However, during August 1992 an outbreak occurred, with cases reported at many schools in children presumably immunised. The objectives of this study were to characterise the epidemic in Cape Town and to determine possible reasons f…

Bleeding from esophageal varices may be a serious or lethal complication of portal hypertension in children. The standard therapy over the past 30 years has been to create a portosystemic shunt. In children physiologic complications leading to high rates of perioperative morbidity and early and late thrombosis with rec…

We have reported on the clinical courses of 4 cases of adult Listeria monocytogenes (Lm) infection, and the autopsy findings of 2 cases, those we have observed over the past 5 years. They were 2 cases of meningitis, 1 case of meningitis and sepsis and 1 case of sepsis. These 4 cases had CML, neoplastic angioendothelios…

BACKGROUND: This study evaluated the effect of CSII on hypoglycemia awareness and on glucose profile in type 1 diabetes (T1D) subjects with repeated non-severe or severe hypoglycemia (NS or SH, respectively). METHODS: We included subjects (1) older than 18 years, (2) with T1D duration of >5 years, (3) on multiple dose…

IMPORTANCE: Few studies have investigated whether the associations between pregnancy-related factors and breast cancer (BC) risk differ by underlying BC susceptibility. Evidence regarding variation in BC risk is critical to understanding BC causes and for developing effective risk-based screening guidelines. OBJECTIVE…

Denosumab is a first-line therapy for osteoporosis, yet the rebound increase in bone turnover markers, rapid bone loss, and elevated fracture risk following its discontinuation have become major challenges in clinical management. This review systematically summarizes the potential mechanisms underlying exacerbated bone…

(Chevrolat) (Coleoptera: Cerambycidae) is a serious wood-boring insect of mulberry trees (spp.). Larvae of this species enter the trunk of the tree and feed on woody tissues.is endemic in several Asian countries, while, in the last decade, it invaded Europe. In the present work, we evaluated trunk injection against thi…

OBJECTIVES: Mastalgia is a common and painful experience among women. This study aimed to determine the prevalence of breast pain, characteristics of the pain, and factors associated with breast pain, particularly those that can be changed. METHODS: This cross-sectional study comprised women aged from 18 to 65 years.…

OBJECTIVE: To better characterize the stroke mortality and risk factors among Asian Indians by using U.S. multiple-cause-of-death and National Health and Interview Survey data. METHODS: Age-adjusted fatal stroke incidence, stroke rate ratio with 95% confidence interval, and average annual percentage change (APC) over…

OBJECTIVE: This report measures fathers' involvement with their children. Father involvement is measured by how often a man participated in a set of activities in the last 4 weeks with children who were living with him and with children who were living apart from him. Involvement is measured separately for children age…