2,589 papers found

Health care professionals' adoption of evidence-based practice (EBP) remains limited, although most health care professionals are familiar with EBP and believe in its value. This systematic review aimed to bring together the best methods used to teach EBP to health professionals. The authors conducted a systematic sear…

AIMS: To conduct a systematic review to identify types and implications of incorrect or incomplete coding or classification within diabetes or between diabetes and other conditions; also to determine the availability of evidence regarding frequency of occurrence. METHODS: Medical Subject Headings (MeSH) and free-text…

BACKGROUND: Prader-Willi syndrome (PWS) is a rare genetic disorder that is identified by the ICD-10 code Q87.11. Although this code has been used in several large studies, its diagnostic validity has not been evaluated. This study assessed the accuracy of the Q87.11 code for identifying individuals with PWS. METHODS:…

: Mean platelet volume (MPV) is a routinely available blood marker that measures platelet size and activation, and it has been evaluated as a potential marker for thyroid malignancies. Platelets participate in tumor genesis through angiogenesis, immune evasion, and metastasis, making them plausible adjuncts for cancer…

INTRODUCTION: Chronic hepatitis C virus (HCV) infection drives T cells into a dysfunctional state due to persistent antigen exposure. This state persists despite viral clearance with previously used interferon-based treatments. Treatment exclusively with direct-acting antivirals (DAAs), introduced in 2014, has revoluti…

OBJECTIVE: The aim of this systematic review was to provide a comprehensive and detailed review of structural and methodological assumptions in model-based cost-effectiveness analyses of systemic metastatic colorectal cancer (mCRC) treatments, and discuss their potential impact on health economic outcome estimates. ME…

OBJECTIVE: To systematically review the literature relating to the impact of multiple co-occurring modifiable risk factors for cognitive decline and dementia. DESIGN: A systematic review and meta-analysis of the literature relating to the impact of co-occurring key risk factors for incident cognitive decline and demen…

BACKGROUND: The occurrence of freezing of gait (FOG) is often observed in moderate to last-stage Parkinson's disease (PD), leading to a high risk of falls. The emergence of the wearable device has offered the possibility of FOG detection and falls of patients with PD allowing high validation in a low-cost way. OBJECTI…

DATA SOURCES: Elsevier's Scopus, Web of Science and Pubmed through Medline identified 431 articles, which were reduced to 206 when duplicates were removed. 8 articles were screened, and 1 excluded after reading the full-text, leaving 7 studies. 6 of these were randomised controlled trials, and 1 a non-randomised contro…

BACKGROUND: Data addressing health-related quality of life (HRQOL) following maxillary reconstruction with free flaps remain scarce. Insight into these outcomes is essential for clinical decision-making. METHODS: A systematic review of Medline, Embase, Web of Science, Cochrane, and Google Scholar was performed for pub…

We combine analytical understanding of resonant dynamics in two-planet systems with machine-learning techniques to train a model capable of robustly classifying stability in compact multiplanet systems over long timescales of [Formula: see text] orbits. Our Stability of Planetary Orbital Configurations Klassifier (SPOC…

Vascularized bone grafts have become one of the first treatment options for scaphoid nonunions and Kienböck's disease. The aim of this study is to review the current body of the literature regarding the use of four vascularized bone grafts (1,2 ICSRA [1,2 intercompartmental supraretinacular artery] graft, 4+5 ECA…

The aim of this systematic review was to present and assess the quality of evidence for learning curve, component positioning, functional outcomes and implant survivorship for imagefree hand-held roboticassisted knee arthroplasty.Searches of PubMed and Google Scholar were performed in line with the Preferred Reporting…

INTRODUCTION: American Indian and Alaska Native (AIAN) communities continue to flourish and innovate in the face of the COVID-19 pandemic. Storytelling is an important tradition for AIAN communities that can function as an intervention modality. To support the needs of AIAN children and caregivers, we (a collaborative…

BACKGROUND: The role of oxidative stress in temporomandibular disorders (TMDs) has been studied using synovial fluid, to evaluate oxidative stress (im)balance and its potential role in the onset and/or progression of the disease. OBJECTIVE: This review aimed to evaluate the association between oxidative stress markers…

PURPOSE OF REVIEW: The growth modulation index (GMI) is defined as the ratio between the time to progression of a new line of treatment and the previous line. This ratio can be used to determine whether the new line of treatment brings a clinical benefit. It has been proposed as an outcome in trials evaluating non-cyto…

BACKGROUND: The management of hepatoblastoma (HB) becomes challenging when the tumor remains in close proximity to the major liver vasculature (PMV) even after a full course of neoadjuvant chemotherapy (NAC). In such cases, extreme liver resection can be considered a potential option. AIM: To explore whether computer-…

BACKGROUND: Metabolic syndrome (MetS) represents a collection of markers associated with cardiovascular morbidity and mortality. Due to its high prevalence and steady increase of the occurrence, prevention or management of MetS is of paramount importance. The aim of our study was to evaluate MetS occurrence and extent…

PURPOSE: Stereotactic body radiation therapy (SBRT) is widely used for pulmonary oligometastatic disease. Guideline-based regimens target a biologically effective dose [Formula: see text]; However, this threshold may not be achievable in patients with limited physiological reserve or ultracentral lesions. We examined o…