2,645 papers found

OBJECTIVES: Despite the multifactorial pathogenesis of malignant transformation, it is assumed that deficiency in some immune mechanisms plays a considerable role in its development. BACKGROUND: Chronically activated immune cells exert tumour-promoting effects directly by influencing the proliferation and survival of…

UNLABELLED: The aim of the study was to evaluate the effect of photocoagulation and range of treatment on visual acuity (VA) in patients with diabetic macular edema. MATERIAL AND METHOD: 56 patients with type II diabetes mellitus--109 eyes were divided into four groups depending on the type of treatment. The evidence…

AIM: The aim of this study was to evaluate the trends in acute adult poisoning data during ten years in university emergency department and determine the factors of hazardous outcome such as severe clinical status, prolonged hospital stay and mortality. MATERIAL AND METHODS: Medical records of 4569 poisoned patients a…

A 13-year-old girl suffered an injury of the left inguinal region in October 2002. The mechanism of the injury was a fall off a merry-go-round with subsequent trailing by the iron frame, which resulted in devastation of the soft tissues and vessels of her left groin. The patient was transported to the Department of Pae…

Hypertrophic cardiomyopathy (HCM) is an autosomal dominant inherited disease of the heart muscle and its main characteristic is unexplained hypertrophy of the left and/or the right ventricle. HCM is the most common genetically determined cardiovascular disease and is prevalent in approximately in 1 of 500 of the popula…

OBJECTIVES: The aim of this study was to measure U-NAG in children with vesicoureteral reflux (VUR) and examine the relationship between selected clinical parameters. BACKGROUND: U-NAG/creatinine ratio is a marker of renal tubular impairment and an increase in this ratio have been reported to affect the kidneys in var…

BACKGROUND: Thyroid nodules are relatively rare in children and adolescents and have a prevalence between 0.2%-1.8%. They are more often malignant in children than in adults and thus an early diagnosis is extremely important. OBJECTIVE: The aim of the study was to analyze the group of pediatric patients with nodular t…

BACKGROUND AND OBJECTIVE: Recent information has highlightened the impact of HA metabolism alterations in vascular permeability through its actions on endothelial glycocalyx and the importance of HA-cell interactions in cell behavior of arterial endothelial and smooth muscle cells. Therefore hyaluronan is thought to in…

OBJECTIVE: Mutations in hemocoagulation factors genes are nowadays routinely examined parameters, important in hereditary trombophilia determination. We have complexly evaluated laboratory data from the 211 unselected patients with venous thrombosis, and compared with the former studies in the same Slovakian population…

Obesity is defined as increased body weight caused by excessive accumulation of fat. Due to a very long period of undernutrition in human history, the contemporary human body regulation mechanisms seem to be biased in favor of preserving fat rather to eliminate it. At the highest risk are populations that suddenly gain…

BACKGROUND: The imbalance in the sex hormones levels is the limited factor which induces disturbances in the uterus function and elevates uterine contractile activity. OBJECTIVES: The aim of our study was to evaluate and compare the direct contractile responsiveness of myometrium to the effects of uterotonic agents--o…

The Medline database from the National Library of Medicine (NLM) contains more than 12 million bibliographic citations from over 4,600 international biomedical journals. One of the interfaces for searching Medline is PubMed, provided by the NLM for free access via the Internet (www.pubmed.gov). Also searchable with the…

This review was conducted to explore the association between endogenous testosterone blood concentrations and cognitive performance among community dwelling postmenopausal women. We searched Ovid MEDLINE, EMBASE, PsycINFO and Web of Science databases for observational studies with at least 100 postmenopausal participan…

Moses technology was born with the aim of controlling the Moses effect present in every single Ho:YAG laser lithotripsy. The capacity to divide the energy pulse into two sub-pulses gained popularity due to the fact that most of the energy would be delivered in the second pulse. However, is this pulse modulation techniq…

AIM: This systematic review is aimed at investigating the biomechanical stress that develops in the maxillofacial prostheses (MFP) and supporting structures and methods to optimize it.. A literature survey was conducted for full-text English articles which used FEA to examine the stress developed in conventional and im…

STUDY DESIGN: Systematic review. OBJECTIVE: The authors aim to review comparative outcome measures between robotic and free-hand spine surgical procedures including: accuracy of spinal instrumentation, radiation exposure, operative time, hospital stay, and complication rates. SUMMARY OF BACKGROUND DATA: Misplacement…

The purpose of this study was to perform a meta-analysis examining the association of isocitrate dehydrogenase (IDH)1/2 mutations with overall survival (OS) and progression-free survival (PFS) in patients with glioblastomas. Medline, Cochrane, EMBASE, and Google Scholar were searched from inception to January 28, 2015,…

The aim of this systematic review was to determine the prognostic value of Bcl-2 immunostaining in patients affected by laryngeal squamous cell carcinoma. An appropriate search was conducted on PubMed to retrieve articles dealing with this topic. A double cross-check was performed on citations and full-text articles by…

The aim of this review was to identify and summarise publications, which have reported clinical applications of upper limb accelerometry for stroke within free-living environments and make recommendations for future studies. Data was searched from MEDLINE, Scopus, IEEExplore and Compendex databases. The final search wa…

INTRODUCTION: Biopsy and histological evaluation of sentinel lymphatic node limits the axillary node dissection only in cases of positive histological finding and decreases the occurrence of postoperative complications related to the axillary node dissection. METHODS: We used radiotracer SentiScint, Medi-Radiopharma L…